Search results for "Stiffness"

SAT0132 DOES JANUS KINASE INHIBITION INDUCED HYPERLIPIDAEMIA ASSOCIATE WITH AN INCREASE OF AORTIC STIFFNESS IN PATIENTS WITH ARTHRITIS? PRELIMINARY R…

2020

Background:Treatment with Janus Kinase inhibitors (JAK-i) (Tofacitinib, Baricitinib) can cause an increase of serum lipids such as total cholesterol, low- (LDL) and high- (HDL) density lipoproteins in patients with arthritis (1). On the other hand, JAK-i can reduce systemic inflammation and have therefore a beneficial effect on the cardiovascular system of treated patients. However, the effects of JAK-i on the CV system have not been adequately examined. In particular, we are not aware of any ’’real world’’ data concerning CV risk of patients receiving JAK-i treatment.Stiffness of the aortic vasculature is a modifiable, valid and independent surrogate predictor of CV risk and can be measure…

Three single loops enhance the biomechanical behavior of the transtibial pull-out technique for posterior meniscal root repair

2017

Purpose: To investigate the effect of applying an additional suture to enhance the biomechanical behavior of the suture–meniscus construct used during the transtibial pull- out repair technique. Methods: A total of 20 fresh-frozen porcine tibiae with intact medial menisci were used. In one half of all speci- mens (N = 10), two non-absorbable sutures were passed directly over the meniscal root from the tibia side of the meniscus to the femoral side (2SS). In other ten specimens, three sutures were passed over the meniscal root (3SS). All specimens were subjected to cyclic loading followed by load-to-failure testing. Displacement of the construct was recorded at 100, 500, and 1000 cycles. Fur…

Orthostatic Hypotension and Complications

2020

Orthostatic hypotension prevalence exponentially increases with age, and an early detection of it can prevent the severe complications it may lead to. Among those, we mention (orthostatic) syncope and falls, cardiovascular diseases, and neurological diseases. Increased blood pressure variability related to standing which can provoke brain hypoperfusion and ischemia, higher arterial stiffness, and activated systematic inflammation, which have both been strongly involved in the pathogenesis of atherosclerosis, finally leading to CVD.

Corrigendum to “Arterial stiffness indexes in acute ischemic stroke: Relationship with stroke subtype” [Atherosclerosis 211 (2010) 187–194]

2016

Hyaluronic Acid in the Treatment of Pain Due to Knee Joint Immobilisation

1995

This open, randomised study was carried out in order to evaluate the safety and efficacy of a course of 5 intra-articular injections (one per week) of hyaluronic acid (HA), administered to patients with pain and joint stiffness resulting from immobilisation of the knee in a plaster cast. The study was made in comparison with an untreated control group. 30 patients of both genders, aged between 18 and 65 years, immobilised in a plaster cast for at least 20 days and presenting with pain and reduced mobility, were included in the study. The results of the study show that, in comparison with the control group, treatment with HA produced a more rapid and effective reduction in pain and increase …

Different Morning Blood Pressure Increases are Associated to a Diverse Microvascular Damage

2007

Usability of photoplethysmography method in estimation of conduit artery stiffness

2011

Three channel photoplethysmography (PPG) signal waveform studies of leg conduit arteries during a provocative occlusion test were performed. PPG waveform second derivative amplitude ratio and arterial pulse wave velocity values showed significant correlations with ultrasound (US) reference method of local and regional arterial stiffness (AS), showing the ability to use PPG for AS change quantitative assessment.

Effects of power training on neuromuscular performance and mechanical efficiency

2007

Effects of power training with stretch-shortening cycle (SSC) exercises on mechanical efficiency (ME) were investigated with 9 young women who trained 3 times a week for 4 months. The training included various types of jumping exercises. Before and after the training as well as after the detraining (2 months) the subjects performed 6 different submaximal exercises with a special sledge apparatus. Each exercise involved 60 muscle actions lasting for a total of 3 min per testing condition. The work intensities were determined individually according to the recordings of distance obtained during the single maximal concentric exercises. The training caused the greatest changes of ME in condition…

Factors Predisposing to Hypertension in Subjects Formerly Born Preterm: Renal Impairment, Arterial Stiffness, Endothelial Dysfunction or 
Something E…

2020

: Subjects formerly born preterm subsequently develop arterial - particularly isolated systolic- hypertension more frequently than their peers born at term. : Numerous factors may influence this predisposition, including an incomplete nephrogenesis, implying the presence of kidneys with a reduced number of nephrons and consequent reduction in haematic filtration, increased sodium absorption and activation of renin-angiotensin-aldosterone system, increased arterial rigidity produced by an elastin deficiency previously observed in anatomic specimens of human immature aorta, and reduced endothelial nitric oxide excretion, due to high blood levels of ADMA, a strong direct inhibitor of nitric o…

Interaction between muscle stiffness and stretch reflex sensitivity after long-term stretch-shortening cycle exercise

1998

The short latency stretch-reflex component (M1) and its interactions with muscle stiffness and with muscle performance were investigated before and after long-term stretch-shortening cycle (SSC) exercise. Dramatic fatigue induced reduction in maximal SSC performance capability, and electromyographic activity was accompanied by a consistent decrease in the M1 reflex component and eccentric peak stiffness of the muscle. It can be suggested, therefore, that the decreased muscle performance is not simply a direct effect of central or peripheral fatigue, but is partly due to impairment of the ability to utilize stiffness-related elastic energy.