Search results for "Stone"
showing 10 items of 1137 documents
Cytotoxic effects induced by JA47, a novel histone deacetylase inhibitor (HDACi), on MDA-MB231 breast cancer cells
2012
JA47, a new histone deacetylase inhibitor that induces cytotoxic effects on triple-negative MDA-MB231 breast cancer cells in vitro
2012
Biological effect of an hybrid anticancer agent based on kinase and histone deacetylase inhibitor on breast cancer cells
2014
Hydroxamic acid-containing histone deacetylase inhibitors potentiate the antiproliferative and apoptotic effects induced by the ribonucleotide reduct…
2008
Rat PIPPin is probably part of a large complex of RNA-binding proteins
2012
Throughout rat brain development, expression of histones variants is mainly regulated at the post-transcriptional level. We previously cloned two cDNAs encoding, respectively, PIPPin (or CSD-C2), a brain-enriched protein able to bind the 3’end of H1° and H3.3 mRNAs, and LPI (longer isoform of PEP-19). Both PEP-19 and LPI are brain-specific. By western blot, we found that PIPPin expression in PC12 cells is enhanced by NGF-induced differentiation. We investigated the RNA-binding properties of the three proteins using their 6 histidine-tagged recombinant fusions and found that they all bind H1° and H3.3 RNAs. Since PEP-19 and LPI are camstatins, we also analyzed whether calmodulin could interf…
Role of RNA-binding proteins in the replication-independent expression of H1° and H3.3 histone variants
2012
Contributo alla conoscenza delle proprietà termofisiche delle murature storiche palermitane
2014
This paper presents the preliminary findings of in situ measurements of thermal transmittance taken in a monumental complex in Palermo. The objective of energy efficiency, one of the main aspects of sustainable construction, is now relevant also for historic architecture. The research aims at analysing the energy performance of the stone walls of the complex, characterized by various thickness, age and construction features. Measurements are taken in accordance with the international standard ISO 9869:1994. The U-values so obtained are compared with tabular data from the Italian standard UNI/TS 11300-1:2008 and with values calculated following the UNI EN ISO 6946:2008. Nine preliminary meas…
Plato and Antisthenes in the Phaedo: A Reflexive Reading. Part One
2019
The purpose of this study is not so much to show the presence of Antisthenes in the dialogue, but rather to examine what Plato alludes to. The controversy over ideas between the two Socratics is historically very well-attested, as can already be seen in the Cratylus. Thus, it is reasonable to assume that this controversy must have affected Plato when he was writing a dialogue in which the importance of ideas and his new logic is undeniable. Hence, this paper will investigate the following question: what impact could Antisthenes’ denominative and definitory logic have on the equally denominative and definitory logic presented in the Phaedo given that the latter work in all probability preced…
Predation on sea urchin by Marthasterias glacialis (L.).
2013
Architetture all'ombra del vulcano: il comprensorio etneo in età moderna. Architecture in the Shadow of the Volcano: the Etna Region in the Early Mod…
2017
Tra le molteplici declinazioni che investono il rapporto architettura natura un caso particolarmente pregnante è quello dei contesti vulcanici, tanto per le implicazioni che riguardano la ricerca estetica e gli aspetti visivi, quanto la costruzione e la composizione materica degli edifici realizzati in tali contesti. La fascinazione suscitata dalle eruzioni vulcaniche attraverso i secoli ha certamente contribuito alla persistenza di miti e alla formazione di un immaginario collettivo, fino alla costruzione di identità locali radicate in territori fortemente caratterizzati, con significativi riflessi anche nella sfera architettonica. Per altro verso, la disponibilità di un’ampia gamma di mat…