Search results for "Study"
showing 10 items of 15483 documents
Population‐based study of the treatment and prognosis of carcinoma of the rectum
1997
Background Few population-based studies address the issue of treatment of carcinoma of the rectum (15 cm or less from the anal vcrge) both from surgical and epidemiological aspects. Methods Some 827 patients were analysed in the cancer registry of the Cote-d'Or (Burgundy, France) from 1976 to 1990 (493 931 inhabitants). Results Resection for cure increased from 57.2 per cent before 1981 to 77.0 per cent after 1985 (P <11.001), and the proportion of Dukes A and B cascs from 35.8 to 52.5 per cent (P< 0.001). Among patients resected for cure, continence-preserving resections were performed more frequently during the 1986-1990 period (48.0 per cent) than during the two previous 5-year periods (…
Prevention of thromboembolic complications in patients with superficial-vein thrombosis given rivaroxaban or fondaparinux: the open-label, randomised…
2017
Summary Background Superficial-vein thrombosis can lead to deep-vein thrombosis and pulmonary embolism. Rivaroxaban, an oral factor Xa inhibitor, might simplify treatment compared with fondaparinux because it does not require daily subcutaneous injection and is cheaper. We compared efficacy outcomes in patients with superficial-vein thrombosis and additional risk factors given either rivaroxaban or fondaparinux to assess whether rivaroxaban is non-inferior to fondaparinux in the prevention of thromboembolic complications. Methods In this open-label, masked endpoint, randomised, non-inferiority phase 3b trial, we recruited patients aged 18 years or older with symptomatic superficial-vein thr…
Ageing and sexuality
2016
Abstract Sexuality is a dimension that concerns human health with profound implications not only in the biological and psychological aspects, but also in the social and cultural dimensions, affecting all ages of life. Sexuality in old age is still conditioned by biases, prejudices and from a stereotyped vision, which considered older people as “asexual”, in spite of several studies and surveys showing that older persons have sexual potential to express. In population surveys, a fair number of men and women aged over 60 years reported having sex at least once a month. The most influential predictor of sexual activity seems to be the physical health in older men, and the quality of the relati…
Obesity, Adipokines and Metabolic Syndrome in Polycystic Ovary Syndrome
2012
The complex mechanisms linking fat excess to metabolic syndrome are not well understood, but several experimental studies have shown that altered production of adipokines plays a main role in development and progression of this disorder. In particular, reduced secretion of adiponectin has a crucial role in inducing insulin resistance but also in determining the clustering of elevated triglycerides and small, dense LDL particles. Increased leptin secretion may be responsible for sympathetic nervous system overactivity and hypertension, while reduced omentin may have an important permissive role in the development of atherogenic processes. Finally, cytokines and other adipokines (resistin, vi…
Dietary strategy for prevention and management of dyslipidemia: international guidelines
2012
Primary prevention of cardiovascular disease should begin with a detailed metabolic study of our patients who must follow a nutritional therapy. Recently, new guidelines ESC/EAS 2011 on the treatment of dyslipidemia have been drawn up, according to which it is possible to arrive at desirable values of cholesterol and triglycerides with a synergy between drug treatment and adequate diet therapy. At this time, Mediterranean diet has been undergoing a radical transformation: there is hyperalimentation of the Mediterranean diet in all its components. The effectiveness of the Mediterranean diet on the reduction of lipids has been demonstrated, and the problem is how to implement this diet in the…
Prevalencia de los trastornos del espectro autista: revisión de datos
2016
Published data on the prevalence of autism spectrum disorders point to a significant increase in this indicator. This increase is being studied in numerous publications of analysis, meta-analysis and systematic reviews. The prevalence indicates the proportion of people who suffer at a given time or are diagnosed with a disease. The consequences of the increasing prevalence are relevant from the point of health, social and educational, but especially relevant when as is the case, the cause of the disorder is unknown. It is in this sense that the prevalence study gains importance in order to delimit various circumstances that may give clues to the possible cause or causes that generate disord…
P-0023 Gastric Cancer in Latvia in 1980 – 2010
2012
ABSTRACT Introduction According to GLOBOCAN 2008 data gastric cancer currently is the fourth most common cancer worldwide and the second most common cause of cancer death. The objective of this study was to get comparable data on gastric cancer for 30 years period, to analyze the trends of incidence and mortality in Latvia and to compare with situation in other countries. Methods Incidence and mortality data from 1980 to 2010 in Latvia were obtained from the National Health Service. IARC (GLOBOCAN 2008) database was used for international comparisons. Incidence and mortality rates were age standardized to the World Standard Population and expressed per 100,000 population. Results There were…
Bibliometric analysis of core journals which publish articles of physical therapy on aging.
2020
Objective Increase in population's longevity has led to considerable efforts worldwide on physical therapy aging research. The aim of this study is to identify which are the main scientific journals, as well as the most productive authors, institutions and keywords related to the journals, that have published about physical therapy and aging. Methods Original articles published from 1990 to 2014 were retrieved from the bibliographic database Science Citation Index Expanded of Web of Science Core Collection. After standardization of the bibliographic information, a series of bibliometric indicators was obtained regarding authors, institutions, citation and keywords of the core journals using…
FRI0189 POOLED ANALYSIS OF THE REAL-WORLD EFFECTIVENESS OF BELIMUMAB IN TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS USING MULTI-COUNTRY DATA FROM THE O…
2019
Background: Real-world evidence of belimumab effectiveness in patients with systemic lupus erythematosus (SLE) has been reported separately for several countries through the OBSErve (evaluation Of use of Belimumab in clinical practice SEttings) programme. Objectives: To evaluate the effectiveness of belimumab in patients with SLE using pooled data from the individual OBSErve studies. Methods: This was a post hoc meta-analysis (GSK study 206351) of patient level data pooled from six retrospective observational cohort studies (Argentina, Canada, Germany, Spain, Switzerland, United States of America). Physicians provided data for adults (≥18 years; clinical diagnosis of SLE) who had initiated …
LOW BACK PAIN IN YOUNG TEAM SPORT PLAYERS: A RETROSPECTIVE STUDY
2014
Background Low back pain (LBP) is a common complaint in general population affecting both genders and almost all age-groups. LBP is a common problem in sports as well, even in younger populations. LBP is prone to recur, thus there is a need for studies on the early phases of the problem in different sports. Objective To investigate the prevalence, nature, severity and risk factors of self-reported LBP in young team sport players. Design A retrospective cross-sectional study. Setting Finnish female and male basketball, floorball, ice hockey and volleyball teams. Participants This study is a part of an ongoing cohort study exploring risk factors for sports injuries. Players from 22 teams, a t…