Search results for "Surgery"
showing 10 items of 18739 documents
Cultural Adaptation of the Modified Version of the Conflicts Tactics Scale (M-CTS) in Mexican Adolescents
2019
Several scales are used in Dating Violence studies assuming cross-cultural invariance and equivalence of the measures without making the proper validation in the intended populations. This study focuses on the importance of adapting existing dating violence psychological instruments (as the widely recognized Modified Version of the Conflict Tactics Scale, M-CTS) in diverse adolescent populations adjusting to international validation procedures that ensure the cultural fit of the instrument and the measurement invariance of the construct. We sought to adapt the M-CTS in Mexican adolescents (N = 1861; 57.5% woman) following the ITC Guidelines for Translating and Adapting Test. We made an anal…
Students’ Perceptions of Instructional Rubrics in Neurological Physical Therapy and Their Effects on Students’ Engagement and Course Satisfaction
2021
One of the main challenges faced by physical therapy (PT) students is to learn the practical skills involved in neurological physical therapy (PT). To help them to acquire these skills, a set of rubrics were designed for formative purposes. This paper presents the process followed in the creation of these rubrics and their application in the classroom, noting that students perceived them as valid, reliable, and highly useful for learning. The perception of the validity and usefulness of the rubrics has different closely related dimensions, showing homogeneous values across the students´ sociodemographic and educational variables, with the exception of dedication to studying, which showed a …
Analysis of requirements for valve accuracy and repeatability in high efficiency digital displacement motors
2018
Traditional variable displacement piston machines achieve high efficiency when operating at high displacements, but struggle with poor efficiency at low displacements. The pistons are connected to high pressure and low pressure in conjunction with the output shaft position and the displacement is changed by changing the piston stroke, resulting in almost constant friction, leakage, and compressibility losses independent of displacement. In digital displacement machines, the rotary valve is replaced by two fast switching on/off valves connected to every cylinder. By controlling the fast switching on/off valves, the cylinders can be controlled individually and friction, leakage and compressib…
Tensions and challenges concerning ethics on video research with young children : experiences from an international collaboration among seven countri…
2018
This article and the four videos linked to this article are a result of the earliest experiences in establishing an international research collaboration among seven countries in the Project Social and emotional experiences in transition through the early years. We draw attention to the complex issues surrounding the many processes, beliefs and attitudes about infants in research that permeated our processes of gaining ethical approval for the international study and which posed many challenges for our project. Through a process of reflective analysis, we have identified a range of ethical tensions and issues which the different countries involved in this international study faced in gaining…
Multicenter Italian survey for varicocele treatment in pediatric age.
2013
Fertility problems will arise in about 20% of adolescents with varicocele. (level of evidence: 1). The recommended indication criteria for varicocelectomy in children and adolescents are the following: varicocele associated with a small testis, additional testicular condition affecting fertility, bilateral palpable varicocele, pathological sperm quality (in adolescents older than16 years of age), varicocele associated with a supranormal response to LHRH stimulation test, symptomatic varicocele. Repair of a large varicocele physically or psychologically causing discomfort may be also considered.The aim of this multicenter study is to evaluate the management and treatment of varicocele in dif…
Vascularized lymph node transfer for treatment of extremity lymphedema: An overview of current controversies regarding donor sites, recipient sites a…
2018
As lymphatic microsurgery has become more common, vascularized lymph node transfer ascended to the forefront in many centers for the surgical management of advanced stages of lymphedema showing substantial clinical improvement. However, no consensus has been reached among experts regarding many details of the procedures, including patient selection criteria, type of treatment, donor, and recipient sites and postoperative evaluation of the outcome. Here, we will review these issues and provide the current results of this procedure.
The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes
2019
AbstractEmbryonic development is arguably the most complex process an organism undergoes during its lifetime, and understanding this complexity is best approached with a systems-level perspective. The sea urchin has become a highly valuable model organism for understanding developmental specification, morphogenesis, and evolution. As a non-chordate deuterostome, the sea urchin occupies an important evolutionary niche between protostomes and vertebrates.Lytechinus variegatus(Lv) is an Atlantic species that has been well studied, and which has provided important insights into signal transduction, patterning, and morphogenetic changes during embryonic and larval development. The Pacific specie…
Lexical Substitution and Paraphasia in Advanced Dementia of the Alzheimer Type
2017
Abstract The paper presents the case study of lexical selection in Alzheimer-type dementia. Lexical substitutions in poem recitation and conversations of a Russian speaker, who suffered Alzheimer-type dementia, were analyzed on the background of the lexical retrieval and slip-of-the-tongue phenomena. The classification of the substitutions is worked out on the basis of the links between a target word and its substitutions. The current context plays an essential role as natural priming for a substitution in a poem recitation. Some words have predisposition to be lost; the units belong to the figurative language or to the category of infrequent lexemes. In conversation, the patient masked fai…
Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix
2019
Abstract Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and the Golgi apparatus in eukaryotic cells. The formation of COP I/II complexes at membrane surfaces is an early step in vesicle formation and is mastered by p24, a type I transmembrane protein. Oligomerization of p24 monomers was suggested to be mediated and/or stabilized via interactions within the transmembrane domain, and the p24 transmembrane helix appears to selectively bind a single sphingomyelin C18:0 molecule. Furthermore, a potential cholesterol-binding sequence has also been predicted in the p24 transmembrane domain. Thus, sphingomyelin and/or cholestero…
PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.
2011
We investigated the therapeutic potential of the premature termination codon (PTC) readthrough-inducing drug PTC124 in treating the retinal phenotype of Usher syndrome, caused by a nonsense mutation in the USH1C gene. Applications in cell culture, organotypic retina cultures, and mice in vivo revealed significant readthrough and the recovery of protein function. In comparison with other readthrough drugs, namely the clinically approved readthrough-inducing aminoglycoside gentamicin, PTC124 exhibits significant better retinal biocompatibility. Its high readthrough efficiency in combination with excellent biocompatibility makes PTC124 a promising therapeutic agent for PTCs in USH1C, as well a…