Search results for "Switzerland"
showing 10 items of 98 documents
Differences in Participation and Performance Trends in Age Group Half and Full Marathoners
2014
International audience; Recent studies investigated participation and performance trends in age group half marathoners and full marathoners for a single event. The present study investigated participation and performance trends in age group athletes in all half marathons and full marathons held in a single country during a given period of time. Changes in running performance and age of 226,754 half marathoners and 86,419 full marathoners competing in Switzerland between 2000 and 2010 were analyzed using linear regression analyses. The number of half marathoners increased (P < 0.01) from 2000 to 2010 for both men (+231%) and women (+299%). In contrast, the number of male and female full mara…
Observation of $Z$ production in proton-lead collisions at LHCb
2014
The first observation of $Z$ boson production in proton-lead collisions at a centre-of-mass energy per proton-nucleon pair of $\sqrt{s_{NN}}=5~\text{TeV}$ is presented. The data sample corresponds to an integrated luminosity of $1.6~\text{nb}^{-1}$ collected with the LHCb detector. The $Z$ candidates are reconstructed from pairs of oppositely charged muons with pseudorapidities between 2.0 and 4.5 and transverse momenta above $20~\text{GeV}/c$. The invariant dimuon mass is restricted to the range $60-120~\text{GeV}/c^2$. The $Z$ production cross-section is measured to be \begin{eqnarray*} ��_{Z\to��^+��^-}(\text{fwd})&=&13.5^{+5.4}_{-4.0}\text{(stat.)}\pm1.2\text{(syst.)}~\text{nb} …
Simulations and measurements of beam loss patterns at the CERN Large Hadron Collider
2014
The CERN Large Hadron Collider (LHC) is designed to collide proton beams of unprecedented energy, in order to extend the frontiers of high-energy particle physics. During the first very successful running period in 2010-2013, the LHC was routinely storing protons at 3.5-4 TeV with a total beam energy of up to 146 MJ, and even higher stored energies are foreseen in the future. This puts extraordinary demands on the control of beam losses. An uncontrolled loss of even a tiny fraction of the beam could cause a superconducting magnet to undergo a transition into a normal-conducting state, or in the worst case cause material damage. Hence a multistage collimation system has been installed in ord…
Molecular characterization of 39 de novo sSMC: contribution to prognosis and genetic counselling, a prospective study.
2012
Small supernumerary marker chromosomes (sSMCs) are structurally abnormal chromosomes that cannot be characterized by karyotype. In many prenatal cases of de novo sSMC, the outcome of pregnancy is difficult to predict because the euchromatin content is unclear. This study aimed to determine the presence or absence of euchromatin material of 39 de novo prenatally ascertained sSMC by array-comparative genomic hybridization (array-CGH) or single nucleotide polymorphism (SNP) array. Cases were prospectively ascertained from the study of 65,000 prenatal samples [0.060%; 95% confidence interval (CI), 0.042-0.082]. Array-CGH showed that 22 markers were derived from non-acrocentric markers (56.4%) a…
Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort
2017
Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We aimed to distinguish asthma phenotypes by latent class analysis and to investigate their associations with different obesity parameters in adults using a population-based Swiss cohort (SAPALDIA). We applied latent class analysis to 959 self-reported asthmatics using information on disease activity, atopy, and age of onset. Associations with obesity were examined by multinomial logistic regression, after adjustments for age, sex, smoking status, educational level, and study centre. Body mass ind…
''Sex Difference In Open-water Ultra-swim Performance In the Longest Freshwater Lake Swim In Europe''
2013
Eichenberger, Evelyn | Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph A. | Rosemann, Thomas | Lepers, Romuald | Senn, Oliver; International audience; ''This study examined participation and performance trends in the 26.4-km open-water ultra-swim "Marathon Swim in Lake Zurich," Switzerland. A total of 461 athletes (157 women and 304 men) finished the race between 1987 and 2011. The mean age of the finishers during the studied period was 32.0 +/- 6.5 years for men and 30.9 +/- 7.2 years for women. The mean age of finishers and the age of winners increased significantly across years for both sexes (p 0.05). The swimming time performance remained stable (p > 0.05) for both sexes across …
Trends in net survival from rectal cancer in six European Latin countries: results from the SUDCAN population-based study.
2016
Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare the net survival from rectal cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000-2004 using the Pohar-Perme estimator. For trend analyses, the study-period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain, and Switzerland and from 2000 to 2004 in Belgium and Portugal. These analyses …
Predictor variables for a 100-km race time in male ultra-marathoners.
2010
In 169 male 100-km ultra-marathoners, the variables of anthropometry, training, and prerace experience, in order to predict race time, were investigated. In the bivariate analysis, age ( r = .24), body mass ( r = .20), Body Mass Index ( r = .29), circumference of upper arm ( r = .26), percent body fat (r = .45), mean weekly running hours ( r = –.21), mean weekly running kilometers ( r = –.43), mean speed in training ( r = –.56), personal best time in a marathon ( r = .65), the number of finished 100-km ultra-runs ( r = .24), and the personal best time in a 100-km ultra-run ( r = .72) were associated with race time. Stepwise multiple regression showed that training speed ( p < .0001), me…
INFLUENCE OF ISLET TRANSPORTATION ON PANCREATIC ISLET ALLOTRANSPLANTATION IN TYPE 1 DIABETIC PATIENTS WITHIN THE SWISS-FRENCH GRAGIL NETWORK
2004
The influence of islet transportation on pancreatic islet allotransplantation in type 1 diabetic patients was evaluated within the GRAGIL network.From December 2001 to April 2003, 16 human pancreatic islet transplants were performed in 9 type 1 diabetic patients with an established kidney graft (functioning for at least 6 months) in four centers of the GRAGIL network. Islet isolation was performed in a core laboratory in Geneva, and the islet preparations were shipped by ambulance to each center for transplantation. One month after transplantation, the efficiency of the graft was assessed according to islet transportation time (ITT): ITT less than 2 hours (group 1, n=5), and ITT greater tha…
Obesity after childhood craniopharyngioma--German multicenter study on pre-operative risk factors and quality of life.
2001
Craniopharyngiomas are tumorous embryogenic malformations. As the survival rate after craniopharyngioma is high (92 %), prognosis and quality of life (QoL) in survivors mainly depend on adverse late effects such as obesity.We analyzed 214 children and adolescents with craniopharyngioma. The records of 185 patients (86 %) were available for retrospective analysis of weight profiles and risk factors for obesity. Quality of life (QoL) was measured in 145 patients by the Fertigkeitenskala Münster/Heidelberg score (FMH) and in 77 patients by PEDQOL questionnaire.Eighty-two of 185 patients (44 %) developed severe obesity (body mass index [BMI]3 SD). Obese patients were compared with 79 patients (…