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Combined homozygous factor H and heterozygous C2 deficiency in an Italian family
1988
Three of four children in a family have homozygous (less than 1% of normal) deficiency of factor H of the complement system and both parents, who are first cousins, are heterozygous for the same defect. The father and two of the H-deficient siblings also have a partial C2 deficiency. One of the children with combined deficiencies is affected by systemic lupus erythematosus with nephritis. No increased susceptibility to infections has been observed in the family. H deficiency is inherited in an autosomal codominant manner and is independently transmitted from C2 deficiency and HLA haplotypes. In the homozygous state it is associated with very low serum concentrations of B and C3, barely demo…
Hexanoic acid is a resistance inducer that protects tomato plants againstPseudomonas syringaeby priming the jasmonic acid and salicylic acid pathways
2012
Summary Hexanoic acid-induced resistance (Hx-IR) is effective against several pathogens in tomato plants. Our study of the mechanisms implicated in Hx-IR against Pseudomonas syringae pv. tomato DC3000 suggests that hexanoic acid (Hx) treatment counteracts the negative effect of coronatine (COR) and jasmonyl-isoleucine (JA-Ile) on the salicylic acid (SA) pathway. In Hx-treated plants, an increase in the expression of jasmonic acid carboxyl methyltransferase (JMT) and the SA marker genes PR1 and PR5 indicates a boost in this signalling pathway at the expense of a decrease in JA-Ile. Moreover, Hx treatment potentiates 12-oxo-phytodienoic acid accumulation, which suggests that this molecule mig…
Differential equations for Feynman integrals beyond multiple polylogarithms
2017
Differential equations are a powerful tool to tackle Feynman integrals. In this talk we discuss recent progress, where the method of differential equations has been applied to Feynman integrals which are not expressible in terms of multiple polylogarithms.
The Cinematic Representation of the Wild Child: Considering L'enfant sauvage (1970)
2019
In examining François Truffaut's L'enfant sauvage (1970), I will consider the feral child Victor (Jean-Pierre Cargol) with regard to the film's cinematic portrayal as typifying the cultural construction of a child. Following James R. Kincaid, the figure of the child can be seen as a ‘hollow category’, seemingly featureless in its alleged innocence. As a result, it functions as an adult ‘repository of cultural needs or fears’. For this reason, the child, and especially the feral child, can serve as a projection screen for a variety of different and even opposed questions and symbolic constructions. The film effects this subliminally through the portrayal of Victor. This is mainly achieved b…
Baldus and the Limits of Representation
2018
Most contributions on agency and representation in medieval law tend to look at collegiate offices, not individual ones: when, how and to what extent can a plurality of people be represented by a single individual. For individual offices - that is, offices not representing a collectivity - the approach was typically another. From the king to the magistrate, the office was not necessarily viewed as a different subject from that of the individual person discharging it, but rather construed as a series of powers vested in that person. Influenced by canon lawyers (chiefly, Innocent IV), Baldus de Ubaldis on the contrary approached the individual office in the same way as the collegiate one. Irr…
The holonic approach for flexible production: a theoretical framework
2011
This paper discusses the body of knowledge about Holonic Approach to theoretically demonstrate how Holonic Production System (HPS) can be a convincing choice to overcome the problems of traditional production systems? architectures. Today, enterprises are trying to find ways to manage the growing environmental complexity that is well described by Complex Systems Theory (CST). After the focus on the main problem regarding environmental complexity, the Holonic system and the Holonic Production System will be analyzed. The paper will focus the potential of HPS to adapt and react to changes in the business environment whilst being able to maintain systemic synergies and coordination through the…
A Hybrid Neural Network Architecture for Dynamic Scene Understanding
1997
A hyprdid (neural and symbolic) architecture allowing for a deep understanding of moving scenes is described. The architecture is based on a working and effective integration among three levels of representation of data coming out from external sensors.
Proteinaceous and oligosaccharidic elicitors induce different calcium signatures in the nucleus of tobacco cells.
2005
We previously reported elevated cytosolic calcium levels in tobacco cells in response to elicitors [D. Lecourieux, C. Mazars, N. Pauly, R. Ranjeva, A. Pugin, Analysis and effects of cytosolic free calcium elevations in response to elicitors in Nicotiana plumbaginifolia cells, Plant Cell 14 (2002) 2627-2641]. These data suggested that in response to elicitors, Ca2+, as a second messenger, was involved in both systemic acquired resistance (RSA) and/or hypersensitive response (HR) depending on calcium signature. Here, we used transformed tobacco cells with apoaequorin expressed in the nucleus to monitor changes in free nuclear calcium concentrations ([Ca2+](nuc)) in response to elicitors. Two …
Purification, crystallization and preliminary X-ray studies of sylvaticin, an elicitin-like protein from Pythium sylvaticum.
2003
Sylvaticin belongs to the elicitin family. These 10 kDa oomycetous proteins induce a hypersensitive response in plants, including necrosis and cell death, but subsequently leading to a non-specific systemic acquired resistance (SAR) against other pathogens. Sylvaticin has been crystallized using PEG 2000 MME as a precipitant agent in the presence of nickel chloride. The crystals belong to space group C2, with unit-cell parameters a = 99.29, b = 25.67, c = 67.45 A, beta = 99.66 degrees. Diffraction data were recorded to 2.1 A resolution at a synchrotron-radiation source.