Search results for "TEE"
showing 10 items of 8497 documents
Error messages in relational database management systems: A comparison of effectiveness, usefulness, and user confidence
2021
Abstract The database and the database management system (DBMS) are two of the main components of any information system. Structured Query Language (SQL) is the most popular query language for retrieving data from the database, as well as for many other data management tasks. During system development and maintenance, software developers use a considerable amount of time to interpret compiler error messages. The quality of these error messages has been demonstrated to affect software development effectiveness, and correctly formulating queries and fixing them when needed is an important task for many software developers. In this study, we set out to investigate how participants ( N = 152 ) …
Korruptio ja huono hallinto tutkimuskohteena varhaismodernissa Ruotsissa : näkökulmat, menetelmät ja mahdollisuudet
2021
Artikkelissa käsitellään korruption ja huonon hallinnon tutkimusta menneisyydessä, ennen kaikkea Ruotsin ja Suomen yhteisen historian ajalla. Tarkoituksena on antaa tämänhetkisen tutkimustiedon valossa yleiskuva siitä, mitä teemasta tällä hetkellä tiedetään sekä pohtia tulevan tutkimuksen mahdollisuuksia, ongelmia (mukaan luettuna lähdekriittiset vaikeudet) sekä vastaisen tutkimuksen lähestymistapoja.
Hulevesien laatu ja merkitys Jyväsjärven kuormittajana
2009
Anonymiteetin haasteet Bitcoinin käytössä
2019
Tutkielman tavoitteena on selvittää, tarjoaako viimeisen vuosikymmenen aika- na suosioon noussut kryptovaluutta Bitcoin käyttäjilleen anonymiteettiä. Kryptovaluuttojen anonymiteetin tarkasteluun eivät perinteiseen tiedonsiirtoon liitetyt anonymiteetin teoreemat täysin sovellu ja tästä johtuen on muodostettu kryptovaluuttoja koskeva uusi anonymiteetin määritelmä. Tämän uuden määritelmän mukaisesti anonymiteettia tarkastellessa on selvää, että Bitcoin ei oletusarvoisesti tarjoa käyttäjilleen anonymiteettia. Myös vaihtoehtoisia kryptovaluuttoja on Bitcoinin suosion myötä luotu ja useita Bitcoinin sisällä toimivia palveluja on kehitetty anonymiteettiä silmällä pitäen. Tutkielmassa tarkastellaan…
Pathogenic mechanisms of how human parvovirus breaks self-tolerance
2017
It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological and immunological aspects of how common viruses can initiate autoimmunity were investigated, and human parvovirus B19 (B19V) was employed as a model virus. B19V non-structural protein 1 (NS1), a superfamily 3 (SF3) helicase, initiated DNA damage resulting in cellular apoptosis. The apoptotic bodies (ApoBods) induced by B19V NS1 were purified and characterized. These ApoBods contained viral NS1 proteins with modified autoimmune-associated self-antigens, e.g. DNA, Smith, Apol…
Multispecies coinfections and presence of antibiotics shape resistance and fitness costs in a pathogenic bacterium
2023
Increasing antimicrobial resistance (AMR) poses a challenge for treatment of bacterial diseases. In real life, bacterial infections are typically embedded within complex multispecies communities and influenced by the environment, which can shape costs and benefits of AMR. However, knowledge of such interactions and their implications for AMR in vivo is limited. To address this knowledge gap, we investigated fitness-related traits of a pathogenic bacterium (Flavobacterium columnare) in its fish host, capturing the effects of bacterial antibiotic resistance, coinfections between bacterial strains and metazoan parasites (fluke Diplostomum pseudospathaceum) and antibiotic exposure. We quantifie…
An ancient virus type from extreme environments
2014
Three Phages from a Boreal Lake during Ice Cover Infecting Xylophilus, Caulobacter, and Polaromonas Species
2023
Although the important role of microbes in freshwater is well understood, studies on phage–host systems in such environments during ice cover are completely lacking. Here, we describe the isolation and characterization of three new bacteriophages infecting Xylophilus sp., Caudobacter sp., and Polaromonas sp. from freshwater samples taken under the ice cover of Lake Konnevesi, Finland. Lumi, Kuura, and Tiera bacteriophages have tailed icosahedral virions and double-stranded DNA. Lumi is a siphophage with a genome of 80,496 bp, and Kuura and Tiera are podophages, and their genomes are 43,205 and 45,327 bp in length, resembling viruses in the class Caudoviricetes. Their host ranges were very l…
Internalization of novel non-viral vector TAT-streptavidin into human cells
2007
BMC Biotechnology, 7 (1)
Remarks on regularity for p-Laplacian type equations in non-divergence form
2018
We study a singular or degenerate equation in non-divergence form modeled by the $p$-Laplacian, $$-|Du|^\gamma\left(\Delta u+(p-2)\Delta_\infty^N u\right)=f\ \ \ \ \text{in}\ \ \ \Omega.$$ We investigate local $C^{1,\alpha}$ regularity of viscosity solutions in the full range $\gamma>-1$ and $p>1$, and provide local $W^{2,2}$ estimates in the restricted cases where $p$ is close to 2 and $\gamma$ is close to 0.