Search results for "TENSION"

showing 10 items of 2456 documents

Optical Coherence Tomography Angiography of Optic Disc in Eyes With Primary Open-angle Glaucoma and Normal-tension Glaucoma.

2019

PURPOSE To examine vessel density (VD) properties of the optic nerve head in eyes with ocular hypertension (OHT), high-tension glaucoma (HTG), and normal-tension glaucoma (NTG) and to evaluate associations on structural parameters of retinal nerve fiber layer (RNFL). METHODS Three groups of patients with OHT (n=15), HTG (n=36), and NTG (n=22), and a healthy control group (n=23) were included in this study. Peripapillary VD and optic disc flow area were measured using optical coherence tomography angiography, and peripapillary RNFL (pRNFL) thickness was determined. Global and sectoral analysis of optic nerve head vasculature and pRNFL thickness were measured. RESULTS Glaucomatous eyes had lo…

AdultRetinal Ganglion Cellsmedicine.medical_specialtygenetic structuresOpen angle glaucomaOptic DiskNerve fiber layerOcular hypertensionGlaucoma03 medical and health sciences0302 clinical medicineNerve FibersNormal tension glaucomaOphthalmologymedicineHumansLow Tension GlaucomaFluorescein AngiographyIntraocular PressureAgedRetrospective StudiesAged 80 and overmedicine.diagnostic_testbusiness.industryRetinal VesselsMiddle Agedmedicine.diseaseFluorescein angiographyeye diseasesOphthalmologymedicine.anatomical_structureCross-Sectional Studies030221 ophthalmology & optometryOptic nerveFemaleOcular Hypertensionsense organsVisual Fieldsbusiness030217 neurology & neurosurgeryGlaucoma Open-AngleTomography Optical CoherenceOptic discJournal of glaucoma
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PCOS: metabolic impact and long-term management.

2012

Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in women, affecting up to 10% of those in reproductive age. Furthermore, PCOS presents a lifetime risk of type II diabetes, cardiovascular diseases and endometrial cancer. Women with PCOS have increased cardiovascular risk; however, the risk is not the same in all patients and it is necessary to assess an individual risk profile. There is a discrepancy between increased cardiovascular risk at young age and postmenopausal number of cardiovascular events, probablu depending on changes in androgen ovarian function after the forties. However, changes with age of metabolic profile in women with PCOS have not been studied yet an…

AdultSettore MED/09 - Medicina InternaAdolescentComorbiditySettore MED/11 - Malattie Dell'Apparato CardiovascolareMetforminSettore MED/13 - EndocrinologiaDiabetes Mellitus Type 2Cardiovascular DiseasesRisk FactorsObesity AbdominalPCOS Metabolic Syndrome Cardiovascular risk aging insulin resistance hyperandrogenismHypertensionHumansFemaleHydroxymethylglutaryl-CoA Reductase InhibitorsInsulin ResistanceChildAntihypertensive AgentsDyslipidemiasPolycystic Ovary SyndromeMinerva ginecologica
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Phase information of time-frequency transforms as a key feature for classification of atrial fibrillation episodes

2015

[EN] Patients suffering from atrial fibrillation can be classified into different subtypes, according to the temporal pattern of the arrhythmia and its recurrence. Nowadays, clinicians cannot differentiate a priori between the different subtypes, and patient classification is done afterwards, when its clinical course is available. In this paper we present a comparison of classification performances when differentiating paroxysmal and persistent atrial fibrillation episodes by means of support vector machines. We analyze short surface electrocardiogram recordings by extracting modulus and phase features from several time-frequency transforms: short-time Fourier transform, Wigner-Ville, Choi-…

AdultSupport Vector MachineEXPRESION GRAFICA EN LA INGENIERIAPhysiologyBiomedical EngineeringBiophysicsPhase (waves)Sensitivity and SpecificityS-transform general Fourier-family transformCohort StudiesTertiary Care CentersElectrocardiographysymbols.namesakeText miningPhysiology (medical)Atrial FibrillationmedicineHumanscardiovascular diseasesAgedAged 80 and overPrincipal Component AnalysisFourier Analysisbusiness.industryCardiovascular AgentsAtrial fibrillationPattern recognitionMiddle Agedmedicine.diseaseAtrial fibrillationTime–frequency analysisSupport vector machineFourier transformROC CurveFeature (computer vision)Fourier analysisArea Under CurveTime-frequency transformsHypertensionsymbolsArtificial intelligenceMedical emergencybusiness
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Thrombosis factors and oxidant/antioxidant markers in obese and hypertensive women during pregnancy.

2015

To investigate the oxidative profile and thrombotic markers in obese and hypertensive mothers.Thirty obese, 28 hypertensive and 34 healthy control mothers were recruited from Tlemcen Hospital, Algeria. Plasma vitamin C, nitric oxide, superoxide anion, erythrocyte glutathione, malondialdehyde, carbonyl proteins and erythrocyte antioxidant enzyme activities and coagulation markers [protein C, protein S, fibrinogen, prothrombin, antithrombin, activated partial thromboplastin time (APTT), lupus anticoagulants (LACs)] were measured. Changes in plasma urea, creatinine, uric acid, glucose and lipid levels were also determined.Plasma glucose concentrations were high in obese mothers, and plasma ure…

Adultmedicine.medical_specialtyAntioxidantmedicine.medical_treatmentFibrinogenSuperoxide dismutasechemistry.chemical_compoundPregnancyInternal medicineInternal MedicinemedicineHumansObesityCreatinineVitamin CbiologySuperoxidebusiness.industryThrombosisGeneral MedicineMalondialdehydeOxidative StressEndocrinologychemistryCase-Control StudiesHypertensionbiology.proteinUric acidFemaleCardiology and Cardiovascular Medicinebusinessmedicine.drugBlood pressure
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Achievement of treatment targets predicts progression of vascular complications in type 1 diabetes.

2021

Abstract Background and aim To study the association between achievement of guideline-defined treatment targets on HbA1c, low-density lipoproteins (LDL-C), and blood pressure with the progression of diabetic complications in patients with type 1 diabetes (T1D). Methods The study included 355 patients at baseline and 114 patients with follow-up data after 3–5 years. Outcome variables were the progression of diabetic kidney disease, retinopathy, or cardiovascular disease (CVD). We used logistic regression and other machine learning algorithms (MLA) to model the association of achievement of treatment targets and probability of progression of complications. Results Achievement of the target bl…

Adultmedicine.medical_specialtyEndocrinology Diabetes and MetabolismDiseaseLogistic regressionOddsDiabetes ComplicationsMachine LearningEndocrinologyRisk FactorsInternal medicineDiabetes mellitusInternal MedicinemedicineHumansDiabetic NephropathiesGlycated HemoglobinType 1 diabetesbusiness.industryCholesterol LDLMiddle Agedmedicine.diseaseLatviaBlood pressureDiabetes Mellitus Type 1Treatment OutcomeCardiovascular DiseasesHypertensionDisease ProgressionComplicationbusinessRetinopathyFollow-Up StudiesJournal of diabetes and its complications
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Magnetic resonance direct thrombus imaging for pre-operative assessment of acute thrombosis in chronic thromboembolic pulmonary hypertension

2018

Adultmedicine.medical_specialtyHypertension PulmonaryEndarterectomyPulmonary ArteryInternal medicinemedicineMedical imagingHumansThrombusThromboembolic pulmonary hypertensionmedicine.diagnostic_testbusiness.industryThrombosisMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingThrombosisPre operativeTreatment OutcomeChronic DiseasePreoperative PeriodCardiologyChronic thromboembolic pulmonary hypertensionAcute thrombosisPulmonary EmbolismCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
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Maternal Risk Factors for Stillbirth: A Registry–Based Study

2019

Background and Objectives: The number of stillbirths has reduced more slowly than has maternal mortality or mortality in children younger than 5 years, which were explicitly targeted in the Millennium Development Goals. Placental pathologies and infection associated with preterm birth are linked to a substantial proportion of stillbirths. Appropriate preconception care and quality antenatal care that is accessible to all women has the potential to reduce stillbirth rates. The aim of the present study was to assess potential risk factors associated with stillbirth within maternal medical diseases and obstetric complications. Materials and Methods: Retrospective cohort study (2001&ndash

Adultmedicine.medical_specialtyMedicine (General)Intrauterine growth restrictionPreconception CareArticleCohort StudiesDiabetes ComplicationsR5-920PregnancymedicineOdds RatioHumansrisk factorsRegistriesRisk factorreproductive and urinary physiologyRetrospective StudiesPregnancyObstetricsbusiness.industryGestational ageRetrospective cohort studyGeneral MedicineOdds ratiomedicine.diseaseConfidence intervalfemale genital diseases and pregnancy complicationsEuropematernal diseasesHypertensionpopulation characteristicsFemalestillbirthbusinessstillbirth; maternal diseases; risk factorsMaternal AgeMedicina
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C-reactive protein and intercellular adhesion molecule-1 are stronger predictors of oxidant stress than blood pressure in established hypertension

2007

Oxidant stress is implicated in the pathogenesis of atherosclerosis in cardiovascular diseases. Our aim was to test oxidative stress, as 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha), and its relationship with inflammation markers C-reactive protein (CRP) and tumour necrosis factor-alpha (TNFalpha), and endothelial activation assayed as soluble intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 in essential hypertension.In 216 essential hypertensive patients and 55 healthy control individuals, plasma levels of high-sensitivity CRP and TNFalpha, 8-iso-PGF2alpha, ICAM-1 and VCAM-1 were measured in basal conditions. Moreover, basal and 24-h ambulatory blood p…

Adultmedicine.medical_specialtyPhysiologyIntercellular Adhesion Molecule-1Vascular Cell Adhesion Molecule-1InflammationBlood Pressuremedicine.disease_causeDinoprostC-reactive protein oxidant stress hypertensionPathogenesisPredictive Value of TestsInternal medicineInternal MedicinemedicineHumansEndothelial dysfunctionInflammationbiologybusiness.industryTumor Necrosis Factor-alphaC-reactive proteinBlood Pressure Monitoring AmbulatoryMiddle Agedmedicine.diseaseIntercellular Adhesion Molecule-1Oxidative StressBlood pressureEndocrinologyC-Reactive ProteinCase-Control StudiesImmunologyHypertensionbiology.proteinTumor necrosis factor alphamedicine.symptomCardiology and Cardiovascular MedicinebusinessOxidative stressBiomarkers
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Micro-albuminuria as a predictor of cardiovascular damage in essential hypertension

1989

Adultmedicine.medical_specialtyPhysiologybusiness.industryBlood PressureMiddle AgedPrognosisEssential hypertensionmedicine.diseaseBlood Pressure MonitorsCircadian RhythmCardiovascular DiseasesEchocardiographyInternal medicineHypertensionMicro albuminuriaInternal MedicineCardiologyAlbuminuriaHumansMedicineCardiology and Cardiovascular MedicinebusinessGlomerular Filtration RateJournal of Hypertension
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Sympathetic nervous activity and the pressor effect of noradrenaline under chronic?-?-adrenoceptor blockade with labetalol in hypertension

1983

In 14 patients with essential hypertension, the influence of the alpha- and beta-adrenoceptor blocking drug labetalol on blood pressure, heart rate, plasma renin, plasma noradrenaline and pressor effect of exogenous noradrenaline was investigated during long-term treatment. During the initial four weeks of treatment, labetalol at a dose of 400 mg/day showed a slight effect only on supine blood pressure, whereas upright blood pressure was already lowered effectively after the second week of treatment (p less than 0.01). An increase in the mean dose to 850 mg/day had an additional blood pressure-lowering effect (p less than 0.001), whereby a preferential decrease of the orthostatic blood pres…

Adultmedicine.medical_specialtySympathetic Nervous SystemSupine positionPostureAlpha (ethology)Blood PressureEssential hypertensionPlasma renin activityPlacebosNorepinephrineInternal medicineReceptors Adrenergic betaReninDrug DiscoveryHeart ratemedicineHumansDrug InteractionsLabetalolLabetalolGenetics (clinical)Plasma noradrenalineDose-Response Relationship Drugbusiness.industryGeneral MedicineMiddle AgedReceptors Adrenergic alphamedicine.diseaseReceptors AdrenergicEndocrinologyBlood pressureEthanolaminesChronic DiseaseHypertensionMolecular Medicinebusinesscirculatory and respiratory physiologymedicine.drugKlinische Wochenschrift
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