Search results for "TERT"

Higher plants possess two different types of ATX1-like copper chaperones.

2007

Abstract Copper (Cu) chaperones constitute a family of small Cu+-binding proteins required for Cu homeostasis in eukaryotes. The ATX1 family of Cu chaperones specifically delivers Cu to heavy metal P-type ATPases. The plant Arabidopsis thaliana expresses the ATX1-like Cu chaperone CCH, which exhibits a plant-specific carboxy-terminal domain (CTD) with unique structural properties. We show that CCH homologues from other higher plants contain CTDs with structural properties similar to Arabidopsis CCH. Furthermore, we identify a new ATX1-like Cu chaperone in Arabidopsis, AtATX1, which functionally complements yeast atx1Δ and sod1Δ associated phenotypes, and localizes to the cytosol of Arabidop…

Type II keratin cDNAs from the rainbow trout: implications for keratin evolution.

2002

From a teleost fish, the rainbow trout Oncorhynchus mykiss, we have cloned and sequenced cDNAs encoding five different type II keratins. The corresponding protein spots, as separated by 2D-PAGE of trout cytoskeletal preparations, have been identified by peptide mass mapping using MALDI mass spectrometry. Three of the sequenced keratins are expressed in the epidermis (subtype IIe), and two in simple epithelia and mesenchymal cells (subtype IIs). The IIs keratins are both orthologs of human K8. This leaves unsequenced only the trace component S3 of the biochemically established trout keratin catalog. A phylogenetic tree has been constructed from a multiple alignment of the rod domains of the …

"Ma joskus jotakin rakastin" : liikkeen ja sanan välisten suhteiden sekä arkielementtien käytön analyysi Panu Varstalan tanssiteoksessa Onerva

2012

Tutkimuksen kohde on Panu Varstalan tanssiteos Onerva. Tutkimus käyttää teoriapohjanaan Gèrard Genetten transtekstuaalisuuden termistöä ja soveltaa sitä tanssiteoksen tulkintaan. Eräänä tavoitteena on kokeilla, kuinka tanssiteos taipuu kirjallisuudentutkimuksen teorian kautta analysoitavaksi. Genetten teoriaa on otettu käyttöön muun muassa siksi, että Onervan nimi ja muut siihen liittyvät tekstit osoittavat selvästi viittaussuhteiden olemassaolon. Transtekstuaalisuuden muodoista tarkastellaan paikallista intertekstuaalisuutta eli suoria sitaatteja, para- ja metatekstejä eli itse teosta ympäröiviä muita tekstejä, hypotekstuaalisuutta eli teoskokonaisuuden transformaatiosuhdetta toisen teksti…

External sustainability in Spanish economy: bubbles and crises, 1970–2020

2023

We address the issue of the sustainability Spain’s exter-nal debt, using data for the period 1970–2020. To detect episodes of potentially explosive behavior of the Spanish net foreign assets over GDP ratio and the current account balance over GDP ratio, as well as episodes of external adjustments over this long period, we employ a recursive unit root test approach. Our empirical analysis leads us to conclude that there is some evidence of bubbles in the ratio between Spanish net foreign assets and the GDP. In contrast, the evidence that the ratio between the Spanish current account balance and the GDP had explosive subperiods is very weak. The episode of explosive behavior identified in the…

Ankkalinna - portti kahden maailman välillä : Don Rosan Disney-sarjakuvat postmodernina fantasiana

2014

Nietzsche en los ensayos del poeta Gottfried Benn

2002

Nietzsche no sólo fue objeto directo y tema central de varios poemas de Benn, como más adelante se podrá comprobar, sino que también constituye, junto con Goethe, Taine y Heinrich Mann, uno de los autores permanentes y predilectos de sus citas explícitas -más de cien- y es, sin lugar a dudas, el inspirador y la fuente principal de los temas recurrentes de su crítica meditación y de su penetrante mirada, siempre poéticas y poetológicas, sobre la cultura en la primera mitad del siglo pasado.

Dix ans d'archéologie forestière dans le Châtillonnais (Côte-d'Or) : enclos, habitats, parcellaires

2010

National audience; Ces recherches sur les ensembles de structures de pierre sous forêt sont mises en œuvre depuis dix ans et sont inté- grées depuis 2003 dans le P.C.R. ‘Vix et son Environnement', dirigé par C. Mordant, S. Wirth et B. Chaume. Les vestiges étudiés sont implantés dans deux milieux géographiques distincts mais contigus : le plateau calcaire recouvert par la forêt domaniale de Châtillon, et les rebords de la Digeanne et du Brevon qui entaillent ce plateau à l'est et au sud. La prospection présente ici des caractères particuliers liés au couvert forestier. Les relevés G.P.S. sont intégrés dans un S.I.G. et constituent la base de cette étude, dans un va et vient…

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS

2007

Membrane fission is an essential process in membrane trafficking and other cellular functions. While many fissioning and trafficking steps are mediated by the large GTPase dynamin, some fission events are dynamin independent and involve C-terminal-binding protein-1/brefeldinA-ADP ribosylated substrate (CtBP1/BARS). To gain an insight into the molecular mechanisms of CtBP1/BARS in fission, we have studied the role of this protein in macropinocytosis, a dynamin-independent endocytic pathway that can be synchronously activated by growth factors. Here, we show that upon activation of the epidermal growth factor receptor, CtBP1/BARS is (a) translocated to the macropinocytic cup and its surroundi…

Dendropoma lower intertidal reef formations and their palaeoclimatological significance, NW Sicily

1999

Abstract Most carbonate rocky shores of NW Sicily are marked by a coalescence of shells of the gastropod Dendropoma in a construction that is variably developed as a response to wave impact. Here, we review all the available information on these constructions and find that the fossil reefs are reliable sea-level indicators. The thickness of the reef samples never exceeds 30–40 cm below sea-level, whereas all 14 C dates fall within a range of few centuries. Some small fragments ejected by violent sea storms date back to 2500 years cal BP. No samples older than 6200 years cal BP have been detected so far. The present distribution of Mediterranean vermetid platforms should result from a northw…

Late Quaternary Variations in the South American Monsoon System as Inferred by Speleothems – New Perspectives Using the SISAL Database

2018

Here we present an overview of speleothem δ18O records from South America, most of which are available in the Speleothem Isotopes Synthesis and Analysis (SISAL_v1) database. South American tropical and subtropical speleothem δ18O time series are primarily interpreted to reflect changes in precipitation amount, the amount effect, and consequently history of convection intensity variability of convergence zones such as the Intertropical Convergence Zone (ITCZ) and the South America Monsoon System (SAMS). We investigate past hydroclimate scenarios in South America related to the South American Monsoon System in three different time periods: Late Pleistocene, Holocene, and the last two millenni…