Search results for "TESTOSTERONE"

The occurrence of serological H-Y antigen (Sxs antigen) in the diandric protogynous wrasse, Coris julis (L.) (Labridae, Teleostei)

1987

Abstract The serological sex-specific (Sxs) antigen (previously called ‘H-Y antigen’) has been shown, in various vertebrate species ranging from fish to mammals, to be characteristic of the heterogametic sex. We studied a protogynous hermaphrodite, Coris julis , in order to examine whether the change of a female to a secondary male also involves a change in the Sxs-antigen phenotype. The (homogametic) females of this species were found to be Sxs negative, while both primary and secondary males were Sxs positive. This was true not only for gonads but also for nongo-nadal tissues. The administration of androgen to females is known to cause sex inversion in this species; we were able to demons…

Masculine (Low) Digit Ratios Predict Masculine Food Choices in Hungry Consumers

2021

Abstract This study investigated the link between individuals’ 2D:4D digit ratio (a biomarker associated with prenatal testosterone exposure) and their inclination to make masculine food choices. Furthermore, the study investigated whether this potential association would be moderated by consumers’ levels of hunger (vs. satiation). Participants (N = 216; 50% female) made a set of binary food choices between items pretested to be perceived as masculine (vs. feminine) and indicated the lengths of their second (2D) and fourth (4D) digits (i.e., index and ring fingers), which were used to calculate their 2D:4D digit ratios. Additionally, they self-reported their self-perceived gender identity a…

La ratio interdigital D2:D4 y su relación con otros indicadores de androgenización en progenitores de personas con trastornos del espectro autista

2013

The 2D:4D ratio is the quotient between the index and ring finger lengths and is a non-direct indicator of androgenisation. If prenatal testosterone levels in the amniotic fluid are high then the probability increases of developing lower ratio values. It has been suggested that people with autism spectrum disorders (ASD) and their parents may have highly androgenised brains, and for this reason the 2D:4D ratio is used as a marker of such idiosyncrasies. This study aims to analyse if parents of people with ASD differ from the general population in several parameters of androgenisation related to the 2D:4D ratio. The sample was composed of 43 parents of offspring with ASD and 42 controls who …

2D:4D in Men Is Related to Aggressive Dominance but Not to Sociable Dominance

2012

It has been shown that a smaller ratio between the length of the second and fourth digit (2D:4D) is an indicator of the exposure to prenatal testosterone (T). This study measured the 2D:4D of men and assessed dominance as a personality trait to investigate indirectly if the exposure to prenatal T is related to a dominant personality later in life. Results showed that men had a more aggressive dominant personality when having a more masculine (lower) 2D:4D, while there was no relationship between sociable dominance and 2D:4D. Findings from this study indicate that it is important to distinguish different forms of dominance since other studies failed to find relationships between dominance an…

Valor de la testosterona en saliva en el diagnóstico de la enfermedad de Alzheimer

2019

Rewarding effects of 3,4-methylenedioxymethamphetamine (“Ecstasy”) in dominant and subordinate OF-1 mice in the place preference conditioning paradigm

2006

We tested the ability of 3,4-methylenedioxymethamphetamine (MDMA) to induce conditioned place preference (CPP) in dominant and subordinate OF-1 mice subjected to cohabitation and repeated sessions of agonistic confrontation, as well as in non-confronted mice. We selected doses of MDMA (2, 6, 10 mg/kg) previously reported to induce CPP in mice and we measured expression of c-Fos evoked by the treatments in non-confronted mice. MDMA induced c-Fos protein in several corticolimbic regions involved in drug-induced reward. Mice were exposed to brief sessions of agonistic confrontation on 5 consecutive days. Determinations of circulating hormones and drug conditioning tests were carried out on com…

High cognitive sensitivity to activational effects of testosterone in parents of offspring with autism spectrum disorders

2014

Abstract The existence of mild forms of autistic-like characteristics in parents of children with autism spectrum disorders (ASDs) has been defined as a broader autistic phenotype (BAP). Excessive prenatal exposure to testosterone (T) seems to play a role in its development. The aims of this study were to characterize whether ASD parents show masculinized brains or high T prenatal exposure compared to a normative population, using cognitive questionnaires, and also to examine the T level changes in response to different cognitive tasks. ASD parents were found to present higher autistic and lower empathic trait scores than controls. They also have higher T levels and magnitude of T response …

Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation

1995

Rat liver parenchymal cells (PC) were isolated by EDTA perfusion and were purified by a subsequent Percoll centrifugation. The isolated PC had a viability of 95%, as judged by trypan blue exclusion. Freshly isolated PC were cryopreserved with an optimized protocol in a computer-controlled freezer. After thawing, the PC still retained a viability of 89%. The activities of representative xenobiotic metabolizing enzymes were compared between freshly isolated and cryopreserved PC after thawing. The cytochrome P450 content and the cytochrome P450 2C11 isoenzyme activity, determined by hydroxylation of testosterone in intact cells, were not affected by the cryopreservation. The following phase II…

Hormonal differences in intimate partner violence perpetrators when they cope with acute stress: A pilot study

2021

Background: Only a few studies have paid attention to the ability of perpetrators of intimate partner violence (IPVAW) against women to cope with acute stress, including hormonal pa-rameters. In fact, previous studies assessed how salivary testosterone (Tsal) and cortisol (Csal) changed after coping with an acute emotional stressor (directly related to IPVAW), and they con-cluded that an imbalance between the two hormones might be characteristic of these men. Never-theless, they neglected to examine the role of other hormones, such as salivary oxytocin (OXsal), which also seemed to play an important role in behavioral regulation, and whether this response could be generalized to other types…

Testosterone and male mating success on the black grouse leks

1996

On black grouse (Tetrao tetrix) leks females prefer dominant, viable males that have managed to acquire relatively central territories. The immunocompetence hypothesis predicts that, because high levels of testosterone are costly to the immune system, male sexual traits that are controlled by testosterone are likely to serve as reliable indicators of male health. Indeed, testosterone concentrations of black grouse males were highly variable, and strongly correlated with male mating success. This is related to the fact that males with high testosterone levels had most central territories. However, the association of testostestorone level with male mating success was not solely related to cen…