Search results for "TF"

770 Risk Factors Associated with Anemia and Nutritional Status in Infants

2012

Background Growth assessment is an integral part of infants health. An understanding of anemia risk factors is essential to identify the groups that are more vulnerable. The Aim of the study was to identify the risk factors for malnutrition in the vulnerable age group of 6 to 12 months and to evaluate possible related risk factors with anemia. Methods The cross-sectional study which evaluated 206 infants aged between 6–12 months who attended the Pediatric Clinic during the years 2010–2011 for inadequate growth. Mothers were interviewed to collect informations regarding socioeconomic status and nutrition practices. Nutritional status was evaluated by anthropometric measurements using growth …

Recurrent Encephalopathy Induced by Metformin in an Elderly Man

2015

Corrective factors of intestinal microflora disorders in the perinatal period

2019

Intestinal microflora is found at approximately 104 bacteria per ml of intestinal fluid. Although this ecosystem is very diverse with dynamic changes taking place within it, there is a certain stability in the type and number of species, referred to as the core microbiome, found in 95% of the human population. Genetic variation of microorganisms is relatively small, and their functions are strictly defined and highly conservative. The microbiome exists symbiotically with the host, protecting it against colonization by pathogenic microorganisms, providing essential metabolites, and stimulating the immune system. Colonization begins prenatally and its development is greatly influenced by the …

Designing Guarantee Options in Defined Contribution Pension Plans

2015

The shift from defined benefit (DB) to defined contribution (DC) is pervasive among pension funds, due to demographic changes and macroeconomic pressures. In DB all risks are borne by the provider, while in plain vanilla DC all risks are borne by the beneficiary. For DC to provide income security some kind of guarantee is required. A minimum guarantee clause can be modeled as a put option written on some underlying reference portfolio of assets and we develop a discrete model that optimally selects the reference portfolio to minimise the cost of a guarantee. While the relation DB-DC is typically viewed as a binary one, the model can be used to price a wide range of guarantees creating a con…

Determinants of performance drivers in online food delivery platforms: a dynamic performance management perspective

2022

PurposeThis study aims to demonstrate that the Dynamic Performance Management (DPM) framework, integrating performance management with system dynamics modelling, enables decision-makers to identify sustainable strategies in online food delivery platforms, thereby avoiding company failure.Design/methodology/approachThis study undertakes a multistep methodological approach. After the literature review, a retrospective case study approach was used. To build the DPM framework and the system dynamics simulation model, primary and secondary data were collected and analysed.FindingsThis study by adopting the DPM perspective highlights the critical role performance drivers play to assess the viabil…

Brief an Johann G. Herder.

1799

Ms. 930a, Nr. 17, Bl. 43r-44v Garlieb H. Merkel. Brief an Johann G. Herder. Berlin, d[en] 9ten März 1799 Autora rokraksts / Autograph, vācuval. / Deutsch [4] lpp. / S. Attēlu numuri / Bildnummern: 930a-017-1, 930a-017-2-3, 930a-017-4 Wahrscheinlich handelt es sich bei diesem Dokument um ein Konzeptdes Briefes von Merkel an Herder; es ist also nicht gesichert, ob dieser in Reinschrift verfasst undan den Adressaten abgeschickt wurde. Merkel schreibt sehr persönlich über sich selbst und versucht das Bild eines draufgängerischen Lebemannes zu geben, der seinen Horizont, wenn möglich, lieber durch eigene Erfahrungen als durch Buchlektüre erweitern will. Merkel weiß, dass er diese Sichtweise mit …

Euphosantianane A–D: Antiproliferative Premyrsinane Diterpenoids from the Endemic Egyptian Plant Euphorbia Sanctae-Catharinae

2018

Euphorbia species are rich in diterpenes. A solvent extraction of Euphorbia sanctae-catharinae, a species indigenous to the Southern Sinai of Egypt, afforded several premyrsinane diterpenoids (1&ndash

Mitochondrial biogenesis in health and disease. Molecular and therapeutic approaches.

2014

Mitochondrial biogenesis (MB) is the essential mechanism by which cells control the number of mitochondria. Cells respond to different physiologic, metabolic, and pathologic changes by regulating this organelle with high morphological and functional adaptability. A considerable number of proteins, transcription factors, upstream regulatory proteins and secondary mechanisms are involved in MB and the stabilization of new mitochondrial DNA. These MB activators and regulators, including the main participating proteins (e.g. PGC-1α and mtTFA), are candidates for therapeutic intervention in diverse diseases, like neurodegenerative disorders, metabolic syndrome, sarcopenia, cardiac pathophysiolo…

Low concentration of ziprasidone in human milk: a case report

2009

Although second-generation antipsychotics are established as the first-line treatment for schizophrenia, female patients are often excluded from this efficient treatment for safety reasons in pregnancy or whilst breastfeeding. For this reason, research on this subject mostly relies on case reports, although there is a great need to establish modern guidelines for treatment. Milk-to-plasma (M:P) ratios have been reported for clozapine (2.79–4.32; Winans, 2001), olanzapine (0.10–0.84; Gardiner et al. 2003), risperidone/9-OH risperidone (0.10–0.42/0.24–0.50; Gentile, 2004) and aripiprazole (0.18–0.20; Schlotterbeck et al. 2007). According to one case report, the infant ingests 0.09–0.43% of th…

Aripiprazole in human milk

2007

Second-generation antipsychotics are now the established first-line treatment for schizophrenia. However, there are limited data on the use of these compounds in pregnant and breastfeeding women with mental disorders. For ethical reasons, research on these subjects mostly relies on collection of single datasets of cases in order to establish treatment guidelines.