Search results for "TIRAP"
showing 10 items of 12 documents
Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression.
2017
Toll-like receptors (TLRs) and nucleotide-binding oligomerisation domain (NOD)-like receptors (NLRs) are two major forms of innate immune sensors but their role in the immunopathology of stable chronic obstructive pulmonary disease (COPD) is incompletely studied. Our objective here was to investigate TLR and NLR signalling pathways in the bronchial mucosa in stable COPD.Using immunohistochemistry, the expression levels of TLR2, TLR4, TLR9, NOD1, NOD2, CD14, myeloid differentiation primary response gene 88 (MyD88), Toll-interleukin-1 receptor domain-containing adaptor protein (TIRAP), and the interleukin-1 receptor-associated kinases phospho-IRAK1 and IRAK4 were measured in the bronchial muc…
Analysis of Polymorphism C558T of MAL (TIRAP) in Mediterranean Spotted Fever
2014
Analysis of Polymorphism C558T of MAL (TIRAP) in Mediterranean Spotted Fever M. Bova1, L. Scola1, C. Colomba1, L. Vaccarino1, P. Di Gangi1, G. Santini1, G. Giammanco1, C. R. Balistreri1, D. Lio1, L. Titone Lanza Di Scalea1 1University of Palermo, Palermo, Italy Background: In our previous studies, we have demonstrated that cytokine polymorphisms, such as IFNγ +874T/A or IL-17 SNP (7488T/C), might interfere with R. Conorii infection control. In addition, we have reported that +896A/G TLR4 SNP is a component of a genetic background that might influence the clinical outcome of Boutonneuse fever (Mediterranean spotted fever, MSF). The +869G allele, that attenuates receptor signaling, was actual…
Connection between optimal control theory and adiabatic-passage techniques in quantum systems
2012
This work explores the relationship between optimal control theory and adiabatic passage techniques in quantum systems. The study is based on a geometric analysis of the Hamiltonian dynamics constructed from the Pontryagin Maximum Principle. In a three-level quantum system, we show that the Stimulated Raman Adiabatic Passage technique can be associated to a peculiar Hamiltonian singularity. One deduces that the adiabatic pulse is solution of the optimal control problem only for a specific cost functional. This analysis is extended to the case of a four-level quantum system.
Roadmap on STIRAP applications
2019
STIRAP (stimulated Raman adiabatic passage) is a powerful laser-based method, usually involving two photons, for efficient and selective transfer of populations between quantum states. A particularly interesting feature is the fact that the coupling between the initial and the final quantum states is via an intermediate state, even though the lifetime of the latter can be much shorter than the interaction time with the laser radiation. Nevertheless, spontaneous emission from the intermediate state is prevented by quantum interference. Maintaining the coherence between the initial and final state throughout the transfer process is crucial. STIRAP was initially developed with applications in …
Zeno-like phenomena in STIRAP processes
2011
The presence of a continuous measurement quantum Zeno effect in a stimulated Raman adiabatic passage is studied, exploring in detail a sort of self-competition of the damping, which drives the system toward a loss of population and, at the same time, realizes the conditions for optimizing the adiabatic passage.
Stimulated Raman adiabatic passage in a $\Lambda$-system in the presence of quantum noise
2011
We exploit a microscopically derived master equation for the study of STIRAP in the presence of decay from the auxiliary level toward the initial and final state, and compare our results with the predictions obtained from a phenomenological model previously used [P. A. Ivanov, N. V. Vitanov, and K. Bergmann, Phys. Rev. A 72, 053412 (2005)]. It is shown that our approach predicts a much higher efficiency. The effects of temperature are also taken into account, proving that in b-STIRAP thermal pumping can increase the efficiency of the population transfer.
Stimulated Raman adiabatic passage in an open quantum system: Master equation approach
2010
A master equation approach to the study of environmental effects in the adiabatic population transfer in three-state systems is presented. A systematic comparison with the non-Hermitian Hamiltonian approach [N. V. Vitanov and S. Stenholm, Phys. Rev. A {\bf 56}, 1463 (1997)] shows that in the weak coupling limit the two treatments lead to essentially the same results. Instead, in the strong damping limit the predictions are quite different: in particular the counterintuitive sequences in the STIRAP scheme turn out to be much more efficient than expected before. This point is explained in terms of quantum Zeno dynamics.
EFFECT OF LOW-FREQUENCY NOISE ON ADIABATIC PASSAGE IN A SUPERCONDUCTING NANOCIRCUIT
2011
Recent experiments have demonstrated coherent phenomena in three-level systems based on superconducting nanocircuits. This opens the possibility to detect Stimulated Raman Adiabatic Passage (STIRAP) in artificial atoms. Low-fequency noise (often 1/f) is one of the main sources of decoherence in these systems, and we study its effect on the transfer efficiency. We propose a way to analyze low frequency fluctuations in terms of fictitious correlated fluctuations of external parameters. We discuss a specific implementation, namely the Quantronium setup of a Cooper-pair box, showing that optimizing the trade-off between efficient coupling and protection against noise may allow us to observe co…
Detuning effects in STIRAP processes in the presence of quantum noise
2011
The Stimulated Raman adiabatic passage (STIRAP) in three-state systems in the presence of quantum noise is considered. A comparison is made between different models, one based on a phenomenological introduction of decays, one traceable back to a microscopic description of the system-environment interaction. Effects related, to off-resonance in the coupling between the involved states are considered.
Effect of broadband noise on adiabatic passage in superconducting nanocircuits
2010
With the rapid technological progress in quantum-state engineering in superconducting devices there is an increasing demand for techniques of quantum control. Stimulated Raman adiabatic passage (STIRAP) is a powerful method in quantum optics which has remained largely unknown to solid-state physicists. It is used to achieve highly efficient and controlled population transfer in (discrete) multilevel quantum systems[1]. Apart from other potential applications in solid-state physics, adiabatic passage offers interesting possibilities to manipulate qubit circuits, in particular for the generation of nonclassical states in nanomechanical or electromagnetic resonators[2]. In this contribution, w…