Search results for "TLE"
showing 10 items of 2417 documents
Naftas un gāzes rūpniecības ietekmes analīze uz valsts ekonomisko vidi
2020
Valsts, kura ražo un eksportē naftu parasti tiek uzskatīta par attīstības valsti. Kazahstānas Republika ir viena no attīstības valsts piemēriem ar lielām naftas un gāzes rezervēm. Šī darba pirmajās daļās tiek aprakstīta globālās ekonomikas tekošā situācija naftas un gāzes industrijā, un kādu vietu šī nozare ieņem Kazahstānā. Darba autora veiktie pētījumi, iekļauj sevī PESTLE analīzi, kas uzskatāmi parāda naftas un gāzes industrijas ietekmi uz Kazahstānas ekonomiku, ņemot vērā starptautisko korporāciju ietekmi uz tādām nozarēm kā politika, ekonomika, tehnoloģijas un apkārtējā vide. Pētījuma rezultāti attēlo negatīvas un pozitīvas ietekmes faktoru virkni, kuri savukārt var būt paaugstināti va…
Augstākās izglītības iestādes pētnieciskā profila lingvistiskā analīze
2021
Akadēmiskā diskursa pētniecība ir piesaistījusi daudzu valodnieku interesi, taču līdz šim šajā jomā vēl nav veikta lingvistiskā analīze, lai raksturotu augstākās izglītības iestādes pētniecisko profilu. Šī darba mērķis bija kvantitatīvi un kvalitatīvi novērtēt Latvijas Universitātes Humanitāro zinātņu fakultātes pētniecisko profilu, apskatot fakultātes publikāciju virsrakstu lingvistiskās struktūras. Pētījumā tika izmantota diskursa un biežuma analīze, lai analizētu izvēlēto datu kopu un apkopotu secinājumus. Iegūtie dati ļāva secināt, ka Humanitāro zinātņu fakultāte sniedz ieguldījumu pētniecībā, apkopojot un vairojot zināšanas par kultūru un valodu, pētījumos galvenokārt apskatot terminol…
Much ado about nothing? The intendant, the gentilshommes and the investigations into nobility in Burgundy (1664-1670)
2008
In 1664 Louis XIV did not spare the Burgundian nobles where furnishing proof of their entitlement to nobility was concerned. His quest for usurpers, which occurred throughout the French kingdom, generated severe misgivings among the gentilshommes, those nobles who had the right to sit in the provincial estates and feared that members of their Chambre would suffer pointless harassment. However, the process was conducted in an unexpectedly lenient manner, demonstrating that royal authority—through its local representative, the intendant Claude Bouchu—could be employed in a conciliatory fashion. The monarchical system, negotiated as much as imposed, should be understood within the framework of…
Comparison of growth & function of endothelial progenitor cells cultured on deproteinized bovine bone modified with covalently bound fibronectin …
2016
Objectives The objective of this study was to assess and compare the growth and function of Endothelial Progenitor Cells (EPCs) cultured on covalently bonded Vascular Endothelial Growth Factor (VEGF) and covalently bonded Fibronectin (FN) coating on deproteinized bovine bone (DBB) (test samples), compared to non-modified DBB blocks (control sample). Materials and methods The test samples were prepared by plasma polymerization of allylamine onto DBB blocks. Group1 of test samples were prepared with VEGF coating (VEGF-DBB) where as the Group2 test samples were coated with FN (FN-DBB). Non-modified DBB blocks served as a Control. EPCs were isolated and cultivated from buffy coats of peripheral…
Characterization of Membrane-Bound Cyclic Nucleotide Phosphodiesterases from Bovine Aortic Smooth Muscle
1992
This study reports the isolation and characterization of cyclic nucleotide phosphodiesterases (PDEs) associated with membrane fraction in comparison to cytosolic forms from bovine aorta. DEAE-Sephacel chromatography of a solubilized membrane fraction from a homogenate, prepared under isotonic conditions in the presence of protease inhibitors, yielded one major peak of PDE activity that specifically hydrolyzed cAMP and was not stimulated by calmodulin: It appeared to contain two subtypes of PDE. The first subtype belonged to the cyclic GMP (cGMP)-inhibited PDE family, (PDE III): It had an apparent Km value of 0.4 microM and was potently inhibited by cGMP, LY186126, and cilostamide. The secon…
Taste for fat: the 6th taste modality
2016
IF 4.066; International audience
Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.
2005
The heme-enzyme soluble guanylyl cyclase (sGC) is an ubiquitous NO receptor, which mediates NO downstream signaling by the generation of cGMP. We studied the mechanism of action of the anthranilic acid derivatives 5-chloro-2-(5-chloro-thiophene-2-sulfonylamino-N-(4-(morpholine-4-sulfonyl)-phenyl)-benzamide sodium salt (HMR1766) (proposed international nonproprietary name, ataciguat sodium) and 2-(4-chloro-phenylsulfonylamino)-4,5-dimethoxy-N-(4-(thiomorpholine-4-sulfonyl)-phenyl)-benzamide (S3448) as a new class of sGC agonists. Both compounds activated different sGC preparations (purified from bovine lung, or crude from human corpus cavernosum) in a concentration-dependent and quickly reve…
L'anima degli animali. Aristotele, frammenti stoici, Plutarco, Porfirio
2015
E' lecito maltrattare gli animali? E mangiarli? Molto del dibattito odierno sulla natura e sui diritti degli animali ha avuto prodromi antichi, anche se con categorie diverse dalle nostre. Il libro è una selezione di testi chiave sul tema, ritradotti per l'occasione e accompagnati da un commento storico-filologico, aprendo suggestive connessioni con la modernità. Il volume raccoglie l'ottavo e il nono libro della Historia animalium di Aristotele, i frammenti degli stoici sugli animali, i tre trattati di Plutarco sul vegetarianismo e sulla "questione animale" (il De esu carnium, il Bruta animalia ratione uti e il De sollertia animalium) e il De abstinentia di Porfirio
Temporal dynamic of biofilms enhances the settlement of the central-Mediterranean reef-builder Dendropoma cristatum (Biondi, 1859).
2021
Abstract Research on marine invertebrate settlement provides baseline knowledge for restoration technique implementation, especially for biogenic engineers with limited dispersion ability. Previously, we determined that the maturity of a biofilm strongly enhances the settlement of the vermetid reef-builder Dendropoma cristatum. To elucidate settlement-related biofilm features, here we analyse the structure and composition of marine biofilms over time, through microscopic observations, eukaryotic and prokaryotic fingerprinting analyses and 16S rDNA Illumina sequencing. The vermetid settlement temporal increase matched with the higher biofilm coverage on the substratum and the reduction of th…
Tissue expression of the vesicle protein pantophysin
1999
The cell-type restricted expression of cytoplasmic microvesicle membrane protein isoforms may be a consequence of the functional adaptation of these vesicles to the execution of specialized processes in cells of different specialization. To characterize the expression of the vesicle protein pantophysin, an isoform of the synaptic vesicle proteins synaptophysin and synaptoporin, we have prepared and characterized antibodies useful for the immunological detection of pantophysin in vitro and in situ. Using these reagents, we show by immunoblot analyses that pantophysin expression is not homogeneous but differs significantly between various bovine tissues. Furthermore, these differences are not…