Search results for "TLE"
showing 10 items of 2417 documents
Fractional wavelet transform
1997
The wavelet transform, which has had a growing importance in signal and image processing, has been generalized by association with both the wavelet transform and the fractional Fourier transform. Possible implementations of the new transformation are in image compression, image transmission, transient signal processing, etc. Computer simulations demonstrate the abilities of the novel transform. Optical implementation of this transform is briefly discussed.
Patterns in Size and Shedding of Fasciola hepatica Eggs by Naturally and Experimentally Infected Murid Rodents
2002
Using samples collected on the island of Corsica, a comparative study was done of the morphometry of Fasciola hepatica eggs shed by cattle and by naturally and experimentally infected murid rodents (wild Mus musculus and Rattus rattus and Rattus norvegicus Wistar laboratory strain). Eggs shed by murids are smaller in size than those shed by naturally infected cattle. A second study analyzed the number of F. hepatica eggs shed in murid feces at different time intervals, i.e., months, days, and 6-hr periods, by the Kato-Katz technique. Both experimentally and naturally infected black rats (R. rattus) were used, and Wistar rats were experimentally infected and included for comparison. The pres…
Cataclastic solution creep of very soluble brittle salt as a rock analogue
1998
Until about the late 1960s, macroscopically ductile deformation of quartz was seen as a microscopically cataclastic process by most geologists (cf. the origin of the name ‘mylonite’). Undulatory extinction, subgrains, recrystallised grains and even crystallographic preferred orientations were interpreted as due to water-assisted brittle deformation processes. Nowadays, by contrast, the occurrence of these optical microstructures is considered as conclusive and unequivocal evidence for dislocation creep. The abundance of these microstructures in naturally deformed rocks lead to the conclusion that dislocation creep is the most important ductile deformation mechanism within the Earth’s crust.…
Actividad cardíaca vagal, volumen e intensidad de entrenamiento en una atleta de fondo keniata. [Cardiac vagal activity, training mileage, and intens…
2022
El objetivo de este estudio fue analizar las oscilaciones de la actividad cardíaca parasimpática (ACP) en un mesociclo de una atleta keniata. La variabilidad de la frecuencia cardiaca (VFC) se midió durante tres semanas. En la primera semana (W1) el volumen de entrenamiento fue 120,55 km, en la segunda (W2) 96,71 km y en la tercera (W3) 79,45 km. Se analizó la media semanal de los intervalos (R-R), la expresión logarítmica (Ln) del cuadrado de la raíz media de la unión de los intervalos R-R adyacentes (LnrMSSD), la desviación estándar de los intervalos R-R (LnSDNN), la frecuencia cardíaca media (FC) de cada sesión y las fluctuaciones diarias de LnrMSSD (LnrMSSDCV). Se observaron incrementos…
The Growth of Greater Manila
2017
Manila is one of the largest megacities in the world. It has grown from the original settlements at the mouth of the Pasig River and the walled Spanish city of Intramuros. The American period saw major plans drawn by architect/planner Daniel Burnham to transform Manila in a US-style capital city, while the Commonwealth saw new plans to create a capital, Quezon City, also largely inspired by American models such as Washington DC. Those plans were only partially implemented. Today, Manila has become a complex metropolis, with several business centers taking over from downtown Manila. Among them, Makati, Ortigas and Bonifacio Global City appear as the true engines of economic growth in the cou…
Sequencing, De Novo Assembly and Annotation of the Colorado Potato Beetle, Leptinotarsa decemlineata, Transcriptome
2012
Background. The Colorado potato beetle (Leptinotarsa decemlineata) is a major pest and a serious threat to potato cultivation throughout the northern hemisphere. Despite its high importance for invasion biology, phenology and pest management, little is known about L. decemlineata from a genomic perspective. We subjected European L. decemlineata adult and larval transcriptome samples to 454-FLX massively-parallel DNA sequencing to characterize a basal set of genes from this species. We created a combined assembly of the adult and larval datasets including the publicly available midgut larval Roche 454 reads and provided basic annotation. We were particularly interested in diapause-specific g…
Species-dependent stereospecific serum protein binding of the oral anticoagulant drug phenprocoumon
1978
13 mammalian species are classified into 3 clearcut groups with respect to the stereospecific serum protein-binding of phenprocoumon: 2 groups showing opposed stereospecific binding characteristics and a 3rd group exhibiting no stereospecific binding. Structural differences in the albumin molecule account for these stereospecific differences in serum protein-binding.
Novel inulin-based mucoadhesive micelles loaded with corticosteroids as potential transcorneal permeation enhancers
2017
In this work a new copolymer of inulin (INU) derivatized with ethylendiamine (EDA) and retinoic acid (RA), named INU-EDA-RA, was synthetized, characterized and employed to produce micelles as carriers for topical administration of corticosteroids for the potential treatment of diseases of posterior eye segment. Spectroscopic analysis confirmed a molar derivatization degree of 11.30 and 4.30% in EDA and RA, respectively. INU-EDA-RA micelles are capable of strong mucoadhesive interactions which result time-independent and stable over time but concentration depending. Moreover micelles are able to encapsulate efficiently from 3 to 13% (w/w) of lipophilic drugs, as dexamethasone, triamcinolone …
Microfibrillar polymeric ocular inserts for triamcinolone acetonide delivery.
2019
Abstract Despite eye drops generally represent the most convenient, simple and patient-friendly formulations to treat ocular diseases, they suffer from poor retention on the ocular surface and low drug bioavailability leading to the necessity of prolonged and continuous treatment over time. Therefore, ocular insert could represent an innovative way to benefit from ocular topical administration while minimizing all the relevant limitation related to this route of administration. Polymeric non-erodible mucoadhesive ocular inserts should be comfortable and should rapidly adhere on the ocular surface, remain in situ for prolonged period, assure a reproducible and controlled drug release as well…
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin
2013
Artemisinin is a drug, widely used in malaria treatment. As the binding affinity of artemisinin and its derivatives dihydroartemisinin and artesunate to blood serum proteins might influence the effectiveness of the drug, binding of artemisinin and derivatives to serum albumin was studied under near physiological conditions. Binding kinetics indicate a simple, single-step association process for all artemisinin derivatives. The determined changes in enthalpy and entropy upon drug binding clearly indicate that hydrophobic forces are most important for artemisinin and dihydroartemisinin binding, whereas binding of artesunate is governed by both hydrophilic and hydrophobic forces. Key residues,…