Search results for "TOBACCO USE"

showing 10 items of 65 documents

Smoking cessation opportunities in severe mental illness (tobacco intensive motivational and estimate risk — TIMER—): study protocol for a randomized…

2019

There is an increased risk of premature death in people with severe mental illness (SMI). Respiratory disorders and cardiovascular disease are leading causes of increased mortality rates in these patients, and tobacco consumption remains the most preventable risk factor involved. Developing new tools to motivate patients towards cessation of smoking is a high priority. Information on the motivational value of giving the lung age and prevention opportunities is unknown in this high-risk population. In the context of community care, screening and early detection of lung damage could potentially be used, together with mobile technology, in order to produce a prevention message, which may provi…

Health Knowledge Attitudes PracticeBipolar DisorderTime FactorsWireless technology:Phenomena and Processes::Physical Phenomena::Time::Time Factors [Medical Subject Headings]medicine.medical_treatmentHealth Behavior:Psychiatry and Psychology::Mental Disorders::Mood Disorders::Affective Disorders Psychotic::Bipolar Disorder [Medical Subject Headings]:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Tobacco Use::Smoking [Medical Subject Headings]Medicine (miscellaneous)EsquizofreniaSmoking PreventionSeverity of Illness Indexlaw.invention:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Tecnología inalámbricaStudy ProtocolPulmonary Disease Chronic Obstructive0302 clinical medicineRandomized controlled triallawEnfermedad pulmonar obstructiva crónicaMulticenter Studies as TopicPharmacology (medical)Prospective Studies030212 general & internal medicineProspective cohort studyLungRandomized Controlled Trials as Topic:Psychiatry and Psychology::Behavioral Disciplines and Activities::Schizophrenic Psychology [Medical Subject Headings]lcsh:R5-920:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Clinical Trials as Topic::Controlled Clinical Trials as Topic::Randomized Controlled Trials as Topic [Medical Subject Headings]COPDeducation.field_of_study:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior [Medical Subject Headings]Chronic obstructive pulmonary diseaseSmokingTrastorno bipolar:Anthropology Education Sociology and Social Phenomena::Education::Education Nonprofessional::Health Education::Patient Education as Topic [Medical Subject Headings]Cese del uso del tabacoTobacco cessation:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Patient Acuity::Severity of Illness Index [Medical Subject Headings]Treatment OutcomeScreeningSchizophrenic Psychologylcsh:Medicine (General)medicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings]Bipolar disorderPopulationContext (language use)03 medical and health sciencesPatient Education as Topic:Information Science::Information Science::Communications Media::Telecommunications::Telephone::Cellular Phone::Text Messaging [Medical Subject Headings]Mobile technologySeverity of illness:Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Schizophrenia [Medical Subject Headings]medicine:Diseases::Respiratory Tract Diseases::Lung Diseases::Lung Diseases Obstructive::Pulmonary Disease Chronic Obstructive [Medical Subject Headings]HumansRisk factoreducation:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome [Medical Subject Headings]:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]MotivationText Messagingbusiness.industry:Anatomy::Respiratory System::Lung [Medical Subject Headings]:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation [Medical Subject Headings]medicine.disease:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Clinical Trials as Topic::Multicenter Studies as Topic [Medical Subject Headings]SpainEmergency medicineSchizophreniaSmoking cessation:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Tobacco Use::Tobacco Use Cessation::Smoking Cessation [Medical Subject Headings]Smoking Cessationbusiness030217 neurology & neurosurgeryTrials
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Proliferative verrucous leukoplakia: a proposal for diagnostic criteria.

2009

Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia, which was first described in 1985 by Hansen et al. Since then, various published case series have presented PVL as a disease with aggressive biological behaviour due to its high probability of recurrence and a high rate of malignant transformation, usually higher than 70%. PVL is a long-term progressive condition, which is observed more frequently in women and elderly patients over 60 years at the time of diagnosis. Eventually, PVL tends to become multifocal with a progressive deterioration of the lesions, making it more and more difficult to control. Tobacco use does not seem to have a significant influence on th…

High probabilitymedicine.medical_specialtyPathologyTobacco usebusiness.industryConsensus criteriaDisease:CIENCIAS MÉDICAS [UNESCO]DermatologyOral leukoplakiaOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASProliferative verrucous leukoplakiaEtiologyMedicineHumansSurgeryLeukoplakia OralbusinessGeneral DentistryMedicina oral, patologia oral y cirugia bucal
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Cilomilast counteracts the effects of cigarette smoke in airway epithelial cells.

2010

Abstract Cigarette smoke extracts (CSE) alter TLR4 expression and activation in bronchial epithelial cells. Cilomilast, a phosphodiesterase-4 inhibitor, inhibits cigarette smoke-induced neutrophilia. This study was aimed to explore whether cilomilast, in a human bronchial epithelial cell line (16-HBE), counteracted CSE effects. In particular, TLR4 expression, IP-10 and IL-8 release, lymphocyte and neutrophil chemotactic activity and ERK and IkBa phosphorylation in CSE and LPS-stimulated 16-HBE were assessed. CSE increased TLR4 expression, reduced IP-10 release and lymphocyte chemotactic activity and increased IL-8 release and neutrophil chemotactic activity. Cilomilast reduced TLR4 expressi…

MAPK/ERK pathwayCyclohexanecarboxylic AcidsLymphocyteImmunologyCyclohexanecarboxylic AcidRespiratory MucosaBiologyCell LineSmokeparasitic diseasesNitrilesmedicineHumansLymphocytesCOPDChemotaxisCilomilastInterleukin-8ChemotaxiChemotaxisTobacco Use Disordermedicine.diseaseNeutrophiliaChemokine CXCL10Toll-Like Receptor 4medicine.anatomical_structureGene Expression RegulationPhosphodiesterase 4 InhibitorImmunologyTLR4PhosphorylationLymphocytePhosphodiesterase 4 Inhibitorsmedicine.symptomNitrileHumanmedicine.drugSignal TransductionCellular immunology
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Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large…

2016

PLoS one 11(4), e0152984 (2016). doi:10.1371/journal.pone.0152984

Male0301 basic medicineNicotinic Acetylcholine ReceptorsPhysiologyEvent-Related Potentialslcsh:MedicineReceptors NicotinicElectroencephalography600 Technik Medizin angewandte Wissenschaften::610 Medizin und GesundheitBiochemistryExonCognitionMathematical and Statistical Techniques0302 clinical medicineMedizinische FakultätGermanyMedicine and Health Scienceslcsh:ScienceCerebral CortexClinical NeurophysiologyGeneticsBrain MappingN100education.field_of_studyMultidisciplinarymedicine.diagnostic_testSmokingBrainElectroencephalographyTobacco Use DisorderTemporal LobeFrontal LobeElectrophysiologyNicotinic acetylcholine receptorBioassays and Physiological AnalysisBrain ElectrophysiologyPhysical SciencesRegression AnalysisFemaleAnatomyFunction and Dysfunction of the Nervous SystemStatistics (Mathematics)Research ArticleSignal TransductionAdultTransmembrane ReceptorsImaging TechniquesEndophenotypesCognitive NeurosciencePopulation610NeurophysiologyNeuroimagingSingle-nucleotide polymorphism-Linear Regression AnalysisBiologyResearch and Analysis MethodsPolymorphism Single Nucleotide03 medical and health sciencesDiagnostic MedicineEvent-related potentialReaction TimemedicineHumansddc:610Statistical MethodseducationElectrophysiological Techniqueslcsh:RBiology and Life SciencesProteinsCell BiologyElectrophysiological Phenomena030104 developmental biologyAcetylcholine ReceptorsEndophenotypeCognitive Sciencelcsh:QMathematics030217 neurology & neurosurgeryNeuroscience
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The effects of social anxiety on alcohol and cigarette use across adolescence: Results from a longitudinal twin study in Finland.

2016

Conflicting reports exist on the direction of the relationship between social anxiety (SA) and alcohol/cigarette use (AU/CU) and alcohol/nicotine dependence (AD/ND), with both positive and negative associations reported. A prospective, longitudinal sample of Finnish twins (n = 1,906) was used to test potential explanations for these discrepancies. Specifically, this study used peer, parent, and teacher ratings of SA, and a clinical interview screening item for social anxiety disorder (SAD-Sc) to examine associations between SA and AU/CU and AD/ND from early adolescence into young adulthood. Peer-rated SA was negatively associated with AU, CU, and AD from age 14 through age 22, implying a pr…

Male030508 substance abuseMedicine (miscellaneous)Nicotine0302 clinical medicineTwins DizygoticLongitudinal StudiesProspective StudiesadolescentsYoung adultChildFinlandta515media_commonalcoholSmokingSocial anxietyTobacco Use Disorderta3142twinsAlcoholismPsychiatry and Mental healthClinical PsychologyFemale0305 other medical sciencePsychologymedicine.drugAdultmedicine.medical_specialtyAdolescentAlcohol Drinkingmedia_common.quotation_subjectnikotiiniContext (language use)ArticlePeer GroupYoung Adult03 medical and health sciencesmedicineHumansRisk factorPsychiatryPhobia SocialPeer groupTwins MonozygoticAbstinenceTwin study030227 psychiatrykaksosetGene-Environment InteractionSelf Reportsocial anxietynicotinePsychology of Addictive Behaviors
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Effect of self-regulatory behaviour change techniques and predictors of physical activity maintenance in cancer survivors: a 12-month follow-up of th…

2021

Abstract Background Current knowledge about the promotion of long-term physical activity (PA) maintenance in cancer survivors is limited. The aims of this study were to 1) determine the effect of self-regulatory BCTs on long-term PA maintenance, and 2) identify predictors of long-term PA maintenance in cancer survivors 12 months after participating in a six-month exercise intervention during cancer treatment. Methods In a multicentre study with a 2 × 2 factorial design, the Phys-Can RCT, 577 participants with curable breast, colorectal or prostate cancer and starting their cancer treatment, were randomized to high intensity exercise with or without self-regulatory behaviour change technique…

MaleCancer ResearchTime FactorsCancer survivorsLogistic regressionBody Mass Indexlaw.inventionTobacco UseProstate cancerRandomized controlled trialBehavior TherapylawOdds RatioMedicineRC254-282DeterminantsHigh intensityNeoplasms. Tumors. Oncology. Including cancer and carcinogensBehaviour changeMiddle AgedBehavioural supportEndurance TrainingVDP::Medisinske Fag: 700::Helsefag: 800OncologySelf-regulationRegression AnalysisFemaleColorectal NeoplasmsMonth follow upmedicine.medical_specialtyBehaviour changeMaintenancePhysical activityBreast NeoplasmsSelf-ControlConfidence IntervalsGeneticsHumansExerciseSwedenMotivationCancer och onkologibusiness.industryResearchProstatic NeoplasmsCancerResistance Trainingmedicine.diseaseActigraphyCancer and OncologyQuality of LifePhysical therapybusinessFollow-Up StudiesBMC Cancer
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Effects of bupropion, alone or coadministered with nicotine, on social behavior in mice

2008

Bupropion, administered alone or combined with nicotine, is presently used to treat nicotine dependence. Despite experimental evidence of the complex behavioral actions of this drug, there have been little data reported about its effects on social behavior. Our main aim was to investigate the effects of acute administration of bupropion, alone or plus nicotine, on social interaction in mice. OF1 group-housed male mice were confronted in a neutral cage with an anosmic opponent during a 10 minutes encounter. Time allocated to body care and digging was reduced by administration of bupropion (40 mg/kg) both when administered alone and with nicotine (1 and 0.5 mg/kg). The lowest dose of bupropio…

MaleDrugNicotinemedicine.drug_classmedia_common.quotation_subjectMedicine (miscellaneous)Male miceAnxietyPharmacologyAnxiolyticDrug Administration ScheduleNicotineMiceDopamine Uptake Inhibitorsmental disordersmedicineAnimalsSocial BehaviorNicotine dependenceBupropionmedia_commonPharmacologyBupropionBehavior AnimalLow doseTobacco Use Disordermedicine.diseaseGanglionic StimulantsAggressionPsychiatry and Mental healthExploratory BehaviorPsychologymedicine.drugAddiction Biology
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Is physical activity associated with low-risk health behaviours among 15-year-old adolescents in Finland?

2012

Aims: To investigate the associations between physical activity and the pattern of risk health behaviour consisting of smoking, alcohol consumption, snuff (snus), cannabis, and condom use among 15-year-old adolescents, taking their educational aspirations and family affluence into account. Methods: The data were collected in the Health Behaviour in School-aged Children (HBSC) study in Finland in 2006. Standardised questionnaires were issued at schools to a 15-year-old nationally representative sample, of which 84.5% (1710 pupils) participated. Logistic regression analysis was used to explore the associations between physical activity, pattern of risk health behaviour, family affluence, and…

MaleMarijuana AbuseCross-sectional studyHealth Behaviorphysical activityfamily affluencelaw.inventionCondomsnuoretlawMedicineFinlandeducation.field_of_studybiologyexerciseSmokingAge Factorsta3141General MedicineTobacco Use Disorderriskitekijärisk factorSnusEducational StatusFemaleFamily Relationsmedicine.medical_specialtyTobacco SmokelessAlcohol DrinkingAdolescentPopulationMotor Activityterveyden edistäminenRisk-TakingSex FactorsCondomliikunta-aktiivisuusEnvironmental healthHumansSnuffRisk factorperheen koettu varallisuusPsychiatryeducationbusiness.industryPublic Health Environmental and Occupational Healthbiology.organism_classificationfyysinen harjoitteluHealth promotionCross-Sectional StudiesAdolescent BehaviorCannabisbusiness
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Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

2010

Contains fulltext : 89305.pdf (Publisher’s version ) (Closed access) Smoking is a common risk factor for many diseases. We conducted genome-wide association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers (n = 31,266) and smoking initiation (n = 46,481) using samples from the ENGAGE Consortium. In a second stage, we tested selected SNPs with in silico replication in the Tobacco and Genetics (TAG) and Glaxo Smith Kline (Ox-GSK) consortia cohorts (n = 45,691 smokers) and assessed some of those in a third sample of European ancestry (n = 9,040). Variants in three genomic regions associated with CPD (P < 5 x 10(-8)), including previously identified SNPs at 15q25 repre…

MaleNetherlands Twin Register (NTR)Lung NeoplasmsSingle-nucleotide polymorphismGenome-wide association studyAetiology screening and detection [ONCOL 5]Receptors NicotinicGenetic analysisArticleMolecular epidemiology [NCEBP 1]Cohort Studies03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingOdds RatioGeneticsmedicine/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansCYP2A6Lung cancerAlleles030304 developmental biologyGenetics0303 health sciencesbiologyCHRNA6CHRNA5Hormonal regulation [IGMD 6]SmokingGenetic VariationGenomicsTobacco Use DisorderOdds ratiomedicine.disease3. Good healthPhenotypeEvaluation of complex medical interventions [NCEBP 2]genome-wide association nicotinic acetylcholine-receptors lung-cancer susceptibility locus molecular-genetics heavy smoking adult twins dependence genes snpsbiology.protein/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleAryl Hydrocarbon Hydroxylases030217 neurology & neurosurgeryGenome-Wide Association Study
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Maternal post-natal tobacco use and current parental tobacco use is associated with higher body mass index in children and adolescents: an internatio…

2015

Background: We investigated whether maternal smoking in the first year of life or any current parental smoking is associated with childhood or adolescent body mass index (BMI). Methods: Secondary analysis of data from a multi-centre, multi-country, cross-sectional study (ISAAC Phase Three). Parents/guardians of children aged 6-7 years completed questionnaires about their children's current height and weight, whether their mother smoked in the first year of the child's life and current smoking habits of both parents. Adolescents aged 13-14 years completed questionnaires about their height, weight and current parental smoking habits. A general linear mixed model was used to determine the asso…

MaleParentsPediatricsmedicine.medical_specialtyPediatric ObesityAdolescentCross-sectional studymedicine.medical_treatmentParental smokingOverweighttabaquismeBMImedicineHumansObesityPediatrics Perinatology and Child HealthadolescentsChildtabac efectes fisiològicsBody mass indexparesbusiness.industryinfantsConfoundingSmokingOverweightmedicine.diseaseObesityClinical trialTobacco useCross-Sectional StudiesInternationalPediatrics Perinatology and Child HealthSmoking cessationObservational studyFemalemedicine.symptombusinessBody mass indexobesitatResearch ArticleDemographytrastorns de la nutrició en els infants
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