Search results for "TOMS"

Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

2016

Marco Contoli,1 Paolo Solidoro,2 Fabiano Di Marco,3,4 Nicola Scichilone,5 Angelo Corsico,6 Fulvio Braido,7 Pierachille Santus4,8 1Research Centre on Asthma and COPD, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Cardiovascular and Thoracic Department, Città della Salute, Turin, Italy; 3Department of Health Sciences, University of Milan, Milan, Italy; 4Respiratory Unit, San Paolo Hospital, Milan, Italy; 5Department of Internal Medicine, Section of Pulmonology (DIBIMIS), University of Palermo, Palermo, Italy; 6Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 7Allergy and Respiratory Diseases Clinic, DIMI, University of G…

Naratīva struktūra un kino stils Toma Forda (Tom Ford) filmās “Vientuļais vīrs” (A Single Man, 2009) un “Nakts dzīvnieki” (Nocturnal Animals, 2016)

2017

Bakalaura darbā apskatīta un izpētīta naratīva struktūra un kino stils režisora Toma Forda filmās “Vientuļais vīrs” un “Nakts dzīvnieki”. Kā pētniecības problēmjautājumi tika izvirzīts noskaidrot, vai Fordam ir raksturīga noteikta naratīva struktūra, kura atspoguļo Forda iemantoto naratīva stilu un vai režisoram ir raksturīgs vienots kino stils, un kā tas izpaužas viņa filmās. Teorētiskajā daļā apkopota literatūra par semiotikas, kino valodas, naratīva un kino naratīva teorijām, savukārt, metodoloģijas daļā tiek raksturota naratīva un semiotiskā analīze. Empīriskajā daļā pēc izvēlētās metodoloģijas tiks analizētas augstākminētās kinofilmas – pēcāk, balstoties uz analīžu rezultātiem, varēs v…

Author's reply: Laryngopharyngeal reflux as a potential cause of persistent local neck symptoms after total thyroidectomy.

2020

Blood Component Therapy and Coagulopathy in Trauma: A Systematic Review of the Literature from the Trauma Update Group

2016

Background Traumatic coagulopathy is thought to increase mortality and its treatment to reduce preventable deaths. However, there is still uncertainty in this field, and available literature results may have been overestimated. Methods We searched the MEDLINE database using the PubMed platform. We formulated four queries investigating the prognostic weight of traumatic coagulopathy defined according to conventional laboratory testing, and the effectiveness in reducing mortality of three different treatments aimed at contrasting coagulopathy (high fresh frozen plasma/packed red blood cells ratios, fibrinogen, and tranexamic acid administration). Randomized controlled trials were selected alo…

Transkriptoma analīze akromegālijas pacientiem ar un bez medikamentozās terapijas

2019

Darba mērķis bija veikt somatotrofas hipofīzes adenomas audu transkriptoma analīzi pacientiem, kuri ir vai nav lietojuši medikamentozo terapiju pirms operācijas, analizējot SST/DA analogu izraisītās izmaiņas transkriptomā. Lai to realizētu tika izdalīts totālais RNS no pacientu somatotrofās hipofīzes adenomas audiem un sagatavotas transkriptoma bibliotēkas. Pēc tam iegūtie dati tika analizēti, izmantojot Galaxy platformu un programmu R un R Studio. Pēc datu analīzes tika iegūti 22 statistiski būtiski DEGs un no tiem viens būtiski iesaistīts signālceļš, kā arī intensitātes grafikā tika novērotas divas izteiktas gēnu grupas, kas iedalijās starp pacientiem atkarībā no medikamentozās terapijas.

Clinical symptomatic de novo systemic transthyretin amyloidosis 9 years after domino liver transplantation

2009

Four years ago, Stangou et al. reported a patient who developed clinical symptoms of amyloidosis 8 years after domino liver transplantation (DLT). In order to alleviate the graft shortage, livers from patients with familial amyloidotic polyneuropathy (FAP) are used as domino grafts for other patients under the assumption that several decades will pass before clinical symptoms due to amyloid accumulation emerge. We now report on another case, the third reported case in the literature, of de novo systemic amyloidosis in a 75-year-old woman 9 years after DLT. The patient underwent DLT at 65 years of age for hepatocellular carcinoma exceeding the Milan criteria in hepatitis C cirrhosis. Transar…

A free plate model can predict guided modes propagating in tubular bone-mimicking phantoms

2014

The goal of this work was to show that a non-absorbing free plate model can predict with a reasonable accuracy guided modes measured in bone-mimicking phantoms that have circular cross-section. Experiments were carried out on uncoated and coated phantoms using a clinical axial transmission setup. Adjustment of the plate model to the experimental data yielded estimates for the waveguide characteristics (thickness, bulk wave velocities). Fair agreement was achieved over a frequency range of 0.4 to 1.6 MHz. A lower accuracy observed for the thinnest bone-mimicking phantoms was caused by limitations in the wave number measurements rather than by the model itself.

Stark ionization of atoms and molecules within density functional resonance theory

2013

We show that the energetics and lifetimes of resonances of finite systems under an external electric field can be captured by Kohn–Sham density functional theory (DFT) within the formalism of uniform complex scaling. Properties of resonances are calculated self-consistently in terms of complex densities, potentials, and wave functions using adapted versions of the known algorithms from DFT. We illustrate this new formalism by calculating ionization rates using the complex-scaled local density approximation and exact exchange. We consider a variety of atoms (H, He, Li, and Be) as well as the H2 molecule. Extensions are briefly discussed.

Presbyopia and the aging eye: Existing refractive approaches and their potential impact on dry eye signs and symptoms.

2020

Every part of the human body is subject to aging, including the eye. Increased prevalence of dry eye disease with age is widely acknowledged: aging threatens ocular surface homeostasis, altering the normal functioning of the lacrimal functional unit and potentially leading to signs and symptoms of dry eye. Parallelly, two additional degenerative processes take place within the crystalline lens, leading to presbyopia and cataractogenesis. With continuously increasing life expectancies both conditions are expected to impact society further. Correction strategies for presbyopia and cataracts either directly or indirectly challenge ocular surface additionally. On one hand, contact lens presbyop…

Pain experience and social support of endometriosis patients during the COVID-19 pandemic in Germany – results of a web-based cross-sectional survey

2021

Background Endometriosis is a chronic pain condition in premenopausal women. Pain is mainly characterized by pain intensity and may induce disability in all areas of daily life. Nevertheless, pain is influenced by emotional and social factors as well. Social distancing measures or quarantine, as reaction to rapidly rising infections with the COVID-19 virus due to the SARS-CoV-2 pandemic, were implemented across Europe to prevent the spread of the virus and social distancing measures were imposed by the German government by beginning of March 2020 with initiation of the lockdown by the end of March 2020. The objective of this study was to assess, how social distancing measures during the lo…