Search results for "TOPS"

showing 10 items of 398 documents

Pigment variant of neuronal ceroid-lipofuscinosis

1995

A 6-year-old girl had progressive ataxia, and visual disturbances resulting in blindness. She died in her sleep at age 22 years. She shared with her sister and paternal relatives bilateral pes cavus deformities and impaired deep-tendon reflexes which suggested Charcot-Marie-Tooth disease. Her sister, who also had both polyneuropathy and a progressive central nervous system (CNS) disease, did not have pigmentary retinopathy. At autopsy, the patient was found to have neuronal ceroid-lipofuscinosis (NCL) marked by intraneuronal accumulation of autofluorescent granular lipopigments in ballooned perikarya and conspicuous extraneuronal pigmentation of subcortical grey matter, but without axonal s…

Malemedicine.medical_specialtyPathologyPostmortem studiesNeurologyCentral nervous systemAutopsyBiologyGrey matterEpitheliumNuclear FamilyDiagnosis DifferentialCharcot-Marie-Tooth DiseaseNeuronal Ceroid-LipofuscinosesmedicineNeuropilHumansChildGenetics (clinical)Cerebral CortexNeuronsPigmentationPigments BiologicalAnatomymedicine.diseaseMicroscopy ElectronKidney Tubulesmedicine.anatomical_structureSpinal CordFemaleNeuronal ceroid lipofuscinosisPolyneuropathyAmerican Journal of Medical Genetics
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Right ventricular involvement in anterior myocardial infarction: a translational approach.

2010

Aims The aim of the present study was to evaluate the involvement of the right ventricle (RV) in reperfused anterior ST-elevation myocardial infarction (STEMI). Methods and results Left anterior descending (LAD)-perfused area (using thioflavin-S staining after selective infusion in proximal LAD artery, %), infarct size (using triphenyltetrazolium chloride staining, %), and salvaged myocardium (% of LAD-perfused area) in the right and left ventricle (LV) were quantified in a 90-min LAD occlusion 3-day reperfusion model in swine ( n = 8). Additionally, we studied, using cardiovascular magnetic resonance, 20 patients with a first STEMI due to proximal LAD occlusion treated with primary angiopl…

Malemedicine.medical_specialtyPhysiologymedicine.medical_treatmentHeart VentriclesSus scrofaInfarctionMagnetic Resonance Imaging CineVentricular Function LeftTranslational Research BiomedicalCoronary circulationReperfusion therapyPhysiology (medical)Internal medicineAngioplastyCoronary CirculationOcclusionmedicineAnimalsHumanscardiovascular diseasesMyocardial infarctionProspective StudiesAngioplasty Balloon CoronaryAnterior Wall Myocardial InfarctionAgedbusiness.industryMyocardiumMiddle Agedmedicine.diseaseDisease Models Animalmedicine.anatomical_structureTreatment OutcomeVentricleCirculatory systemcardiovascular systemCardiologyVentricular Function RightFemaleAutopsyCardiology and Cardiovascular MedicinebusinessNuclear medicineCardiovascular research
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The organized subdural blood clot in forensic case work - a case report.

2000

The medico-legal assessment of a subdural haematoma (recent or organized) usually requires some information regarding its cause. Quite often, especially in the absence of a known history of trauma, minor head injuries, which are no longer verifiable, are simply assumed to be the most likely causes. Considering the fact that a subdural haematoma could also be non-traumatic, e.g. in haemorrhagic disorders, cardiac conditions with persistent passive hyperaemia, true inflammatory and degenerative processes of the dura, etc., the medico-legal implication of a possible head injury would require the exclusion of such non-traumatic conditions capable of causing subdural bleeding. In this respect, t…

Malemedicine.medical_specialtySubdural haematomaAutopsyPathology and Forensic MedicineHematomaFatal OutcomeCause of DeathmedicineCraniocerebral TraumaHumansCause of deathAgedAged 80 and overbusiness.industryVascular diseaseHead injuryMedical jurisprudencemedicine.diseaseIntracranial ArteriosclerosisSurgerySkullmedicine.anatomical_structureHematoma SubduralAccidental FallsAutopsybusinessLawForensic science international
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Using multidimensional scaling in model choice for congenital oesophageal atresia: similarity analysis of human autopsy organ weights with those from…

2020

Swine models had been popular in paediatric oesophageal surgery in the past. Although being largely replaced by rodent models, swine experienced a revival with the establishment of minipig models. However, none of them has ever been investigated for similarity to humans. We conducted a pilot study to determine whether three-week old Pietrain piglets and three-month old Aachen Minipigs are suitable for experimental paediatric oesophageal atresia surgery. We tested the operation's feasibility, performed a necropsy, weighed organs, measured organ length and calculated relative weights and lengths, and measured laboratory parameters. We used multidimensional scaling to assess the similarity of…

Malemedicine.medical_specialtySwineSus scrofaAutopsyPilot Projects03 medical and health sciences0302 clinical medicineAnimal modelSimilarity analysisOesophageal surgerymedicineAnimalsHumansModel choiceMultidimensional scalingEsophageal AtresiaGeneral Veterinarybusiness.industryInfantOrgan Sizemedicine.diseaseDisease Models Animal030220 oncology & carcinogenesisAtresiaMultidimensional Scaling AnalysisSwine Miniature030211 gastroenterology & hepatologyAnimal Science and ZoologyFemaleRadiologybusinessLaboratory animals
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Sudden infant death caused by a ruptured coronary aneurysm during acute phase of atypical Kawasaki disease

2001

This article describe's a case of atypical Kawasaki disease (AKD) with lack of typical clinical signs and rapid fatal course in a 2-month-old infant, who 1 week before hospitalization demonstrated rhinitis, coughing without fever, and later conjunctival hyperemia and allergic exanthema on chest and arms. On admittance, labwork highlighted the following: leukocytosis, thrombocytosis, elevated sedimentation rate, and positive C-reactive protein. General conditions remained mediocre for 7 days until sudden death occurred. The autopsy confirmed death caused by cardiac tamponade caused by a ruptured inflammated aneurysm of the left anterior descending coronary artery. We believe that the current…

Malemedicine.medical_specialtyThrombocytosisbusiness.industryVascular diseaseCoronary AneurysmInfantAutopsyMucocutaneous Lymph Node Syndromemedicine.diseaseSudden deathPathology and Forensic MedicineSurgeryFatal OutcomeCardiac tamponadeAcute DiseasemedicineHumansKawasaki diseaseLeukocytosismedicine.symptombusinessComplicationSudden Infant DeathHuman Pathology
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Aortic intramural hemorrhage visualized by transesophageal echocardiography: Findings and prognostic implication

1994

Abstract Objectives. This study describes the transesophageal echocardiographic and follow-up findings in patients with aortic intramural hemorrhage. Background. Localized aortic intramural hemorrhage resulting in layered thickening of the aortic wall seems to represent a variant of acute aortic dissection without communication or a typical moving intimal flap. In autopsy studies this variant, attributed to a rupture of the van vasorum, has been described in 5% to 10% of patients with dissection. Methods. In a prospective transesophageal echocardiographic study in patients with aortic dissection performed between 1986 and 1991, the diagnosis of intramural hemorrhage was established in 15 of…

Malemedicine.medical_specialtyTime FactorsAortic RuptureAorta ThoracicAutopsyDissection (medical)Asymptomaticmedicine.arteryAscending aortamedicineHumansProspective StudiesAortaAgedAortic dissectionAortaAortic Aneurysm ThoracicVascular diseasebusiness.industryPrognosismedicine.diseaseAortic AneurysmSurgeryAortic DissectionDescending aortacardiovascular systemFemaleRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealFollow-Up StudiesJournal of the American College of Cardiology
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Fatal Anaphylactic Shock Ceftriaxone-Induced in a 4-Year-Old Child

2014

One of the most used cephalosporin in clinical practice is ceftriaxone. Anaphylaxis due to the administration of ceftriaxone is considered a rare event. Here, we report a case of fatal anaphylactic shock after the administration of ceftriaxone in a child who had tolerated the drug in past exposures. The allergic pathogenesis is sustained by the clinical data (short time between the inoculation of the drug and the onset of the symptoms; past exposure to the same molecule and probable sensitization) and the postmortem examination findings (polivisceral congestion and intense eosinophilia found in the histological examination).

Malemedicine.medical_specialtymedicine.drug_classCephalosporinDrug Hypersensitivity03 medical and health sciencesFatal Outcome0302 clinical medicineHumansMedicineEosinophilia030216 legal & forensic medicineAnaphylaxisSensitizationRetrospective StudiesHistological examination030201 allergybusiness.industryCeftriaxoneRetrospective cohort studyGeneral Medicinemedicine.diseaseDermatologyAnti-Bacterial Agentsmedicine.anatomical_structureChild PreschoolPediatrics Perinatology and Child HealthEmergency MedicineCeftriaxoneAnaphylactic shockAutopsymedicine.symptombusinessAnaphylaxismedicine.drugPediatric Emergency Care
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Homicide with post mortem dismemberment of the victim with previous amputation of right lower limb: Case report and review of the literature

2018

The dismemberment of a corpse is comparatively rare in forensic medicine and usually performed with different types of sharp tools. The victim is always the victim of a homicide. Dismemberment usually occurs where the killing took place without prior planning by the perpetrator. We report a case of homicide with post mortem mutilation of the victim’s body with previous amputation of right lower limb in which the perpetrator was not identified. At autopsy, several fractures were detected on the cranial vault, and the cause of death was due to skull and brain injuries from multiple blunt force traumas.

Malemedicine.medical_specialtymedicine.medical_treatmenteducationAutopsyDismemberment01 natural sciencespost mortem injurie03 medical and health sciences0302 clinical medicineBluntAmputation TraumaticHomicideCranial vaultmedicineHumansCorpse Dismemberment030216 legal & forensic medicineCause of deathForensic diagnosibusiness.industryGeneral surgery010401 analytical chemistryGeneral MedicineMiddle Agedpeople.cause_of_death0104 chemical sciencesSkullmedicine.anatomical_structureAmputationAutopsyHomicidepeoplebusinessdismembermentHumanMedico-Legal Journal
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A Facilitatory Effect of Perceptual Incongruity on Target-Source Matching in Pictorial Metaphors of Chinese Advertising: EEG Evidence

2020

Using evoked response potentials, we investigated the implicit detection of incongruity during target-source matching in pictorial metaphors of Chinese advertising. Participants saw an image of a product (the target in a visual metaphorical relationship), and then made a same-different judgment in response to a second image (the source in a visual metaphorical relationship) which was (in)congruous to the first image in terms of shape and/or function. We collected behavioral (button-press reaction time and accuracy), and neural (N270, delta and theta band activity) measures. The time-frequency analysis showed faster processing of incongruous visual information. Moreover, shape and conceptual…

Matching (statistics)010504 meteorology & atmospheric sciencesMetaphormedia_common.quotation_subjectExperimental and Cognitive Psychology010501 environmental sciencesElectroencephalography01 natural sciencesPerceptionmedicineResearch ArticlesApplied Psychology0105 earth and related environmental sciencesmedia_commonmedicine.diagnostic_testGeneral NeuroscienceAdvertisingperceptual incongruitynäköhavainnothavaintopsykologiaPsychiatry and Mental healthClinical PsychologymainontaTheta bandmetaforatadvertising pictorial metaphorPsychology (miscellaneous)Psychologytarget-source matchingAdvances in Cognitive Psychology
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Alternatīvu ranžēšāna lietojot metodes TOPSIS modifikācijas ekspertu novērtējumu agregārijai

2018

Bakalaura darbs ir veltīts alternatīvu ranžēšanai. Darba mērķis ir aprakstīt un salīdzināt metodes, kuras par pamatu izmanto metodi TOPSIS. Darbs satur metodes TOPSIS aprakstu, kā arī trīs modifikācijas: TOPSIS ar nestrikto modeli BS, ar eksperta kvalifikācijas vērtējumiem un ar apakškritērijiem. Visas metodes ir ilustrētas ar skaitliskiem piemēriem.

Matemātikadaudzkritēriju uzdevumsTOPSISlēmumu pieņemšanaprioritāšu noteikšana
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