Search results for "TOPS"

showing 10 items of 398 documents

New 1,2,4-oxadiazole nortopsentin derivatives with cytotoxic activity

2019

New analogs of nortopsentin, a natural 2,4-bis(3&prime

anti-cancer agentCell SurvivalAnti-cancer agentsPharmaceutical ScienceAntineoplastic AgentsAntiproliferative activity01 natural sciencesArticlechemistry.chemical_compoundStructure-Activity RelationshipMarine alkaloidsSettore BIO/10 - BiochimicaDrug DiscoveryMoietyHumansPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Cell ProliferationIndole testMolecular Structure010405 organic chemistryAcridine orangeImidazoles2 4-oxadiazole derivativesnortopsentin analogs2 4-oxadiazole derivatives; Anti-cancer agents; Antiproliferative activity; Marine alkaloids; Nortopsentin analogs 1; Antineoplastic Agents; Caco-2 Cells; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; HCT116 Cells; Humans; Imidazoles; MCF-7 Cells; Molecular Structure; Structure-Activity RelationshipPhosphatidylserineCell Cycle CheckpointsNortopsentin analogs 1HCT116 CellsSettore CHIM/08 - Chimica Farmaceutica0104 chemical sciences124-oxadiazole derivative010404 medicinal & biomolecular chemistrychemistryBiochemistry124-oxadiazole derivativeslcsh:Biology (General)ApoptosisCell cultureCancer cellMCF-7 CellsMarine alkaloid2 4-oxadiazole derivativeCaco-2 CellsEthidium bromide
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Biological evaluation of new 1,2,4-oxadiazole topsentin analogs as anticancer agents

2019

anticancer agents topsentin topsentin analogs novel targetsSettore CHIM/08 - Chimica Farmaceutica
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Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity

2019

Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity

antitumor activity topsentin analogs oxadiazole
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The bending triad of the quasi-spherical top molecule SO2F2 in the 550 cm(-1) region

2006

International audience; The analysis of the v(3)/v(7)/v(9) bending triad of SO2F2 has been recently performed with the Watson's Hamiltonian up to octic terms employing 79 rovibrational parameters but including only the first order Coriolis interaction terms, fixed to ab initio values [H. Burger, J. Demaison, F. Hegelund, L. Margules, I. Merke, J. Mol. Struct. 612 (2002) 133-141]. Since SO2F2 is a quasi-spherical top, it can also be considered as derived from the SO42- sulfate ion. We have thus developed a new tensorial formalism in the O(3) > Td > C2v group chain [M. Rotger, V. Boudon, M. Loete, J. Mol. Spectrosc. 216 (2002) 297-307]. This approach allows a systematic development of rovibra…

asymmetric tops010504 meteorology & atmospheric sciencesInfraredAb initioInfrared spectroscopy01 natural sciencesStandard deviation010309 opticssymbols.namesakeQuantum mechanics0103 physical sciencesMoleculePhysical and Theoretical Chemistryinfrared spectroscopySpectroscopy0105 earth and related environmental sciencesmicrowave spectroscopyPhysics[PHYS.PHYS.PHYS-AO-PH]Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]XY(2)Z(2)Rotational–vibrational spectroscopyAtomic and Molecular Physics and Optics[ PHYS.PHYS.PHYS-AO-PH ] Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]symbolsRotational spectroscopyHamiltonian (quantum mechanics)tensorial formalism
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Both contextual regularity and selective attention affect the reduction of precision‐weighted prediction errors but in distinct manners

2021

Predictive coding model of perception postulates that the primary objective of the brain is to infer the causes of sensory inputs by reducing prediction errors (i.e., the discrepancy between expected and actual information). Moreover, prediction errors are weighted by their precision (i.e., inverse variance), which quantifies the degree of certainty about the variables. There is accumulating evidence that the reduction of precision‐weighted prediction errors can be affected by contextual regularity (as an external factor) and selective attention (as an internal factor). However, it is unclear whether the two factors function together or separately. Here we used electroencephalography (EEG) …

auditory perceptiontarkkuusprediction errorsprecisionelectroencephalography (EEG)EEGpredictive codingkuulokuulohavainnothavaintopsykologia
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La autopsia en casos de mala praxis

2002

Después de una escueta referencia a la trascendencia de la práctica de las autopsias clínicas, se aborda el problema de la autopsia forense en los casos de mala praxis. Estos pueden ser de muy distinta naturaleza y de la misma forma, los indicios que dejen en el cadáver van a ser también muy variados. Un problema, que puede ser determinante para la investigación, es el momento en el que se practica la autopsia, que puede ser anterior o posterior a la interposición de la reclamación. Asimismo, el estado del cadáver va a condicionar los resultados, atendiendo fundamentalmente a la fase de putrefacción en que se encuentre. Al poner en relación los tipos de mala praxis con las variedades de mue…

autopsia forenseprueba pericialresponsabilidad profesionalautopsia clínicaPathology and Forensic MedicineCuadernos de Medicina Forense
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Juvenile sudden cardiac death due to congenital coronary ostial valve-like ridges: A case report and literature review

2023

Coronary artery anomalies are a heterogeneous group of congenital disorders affecting the coronary pattern with a characteristic (origin, number, number of hosts, course, etc.). They are rarely found in the population. We report the case of a 21-year-old male who died from sudden cardiac death caused by an isolated coronary ostial obstruction, secondary to a rare anomaly, the presence of a valve-like ridge consisting of a small fold in the Valsalva aortic sinus. The study provides a brief literature review on the pathophysiology, diagnosis, and clinical and medico-legal issues in coronary artery anomaly cases that may be helpful in forensic practice when dealing with sudden cardiac death i…

autopsy – young peopleostial valve-like ridgeCoronary artery anomaliesudden cardiac death.General MedicineMedico-Legal Journal
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New Topsentin analogs as inhibitors of biofilm formation

biofilm Topsentin analogs phatogensSettore CHIM/08 - Chimica Farmaceutica
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Sparassidae from Japan. II. First Pseudopoda species and new Sinopoda species (Araneae: Sparassidae: Heteropodinae)

2002

The genus Pseudopoda is recorded for the first time from Japan. Pseudopoda kasariana sp. nov. (_??_, _??_) and Pseudopoda spirembolus sp. nov. (_??_, _??_) are described from Amami-oshima Island and Okinawajima Island respectively. Four new Sinopoda species are described: Sinopoda albofasciata (_??_), Sinopoda derivata (_??_, _??_), Sinopoda ogatai (_??_, _??_) and Sinopoda stellatops (_??_, _??_). Sinopoda koreana (Paik 1968) is recorded for the first time from Japan. New records of Sinopoda okinawana Jager & Ono 2000 and S. tanikawai Jager & Ono 2000 are presented. Within the genus Sinopoda Jager 1999 the okinawana species-group is newly diagnosed, which is represented by S. albofasciata …

biologyPseudopoda spirembolusEcologyCentral chinaZoologyNewly diagnosedPseudopodabiology.organism_classificationSinopoda koreanaGeographySinopoda okinawanaSinopodaSinopoda stellatopsEcology Evolution Behavior and SystematicsActa Arachnologica
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Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3- b]pyridines, indolyl-thiazolyl-pyrrolo[2,3-b]pyridines and indolylthiazolyl- p…

bis-indolyl alkaloidantitumor activitynortopsentin analoguemarine alkaloid
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