Search results for "TRANSFORMATION"
showing 10 items of 1634 documents
Politics of solidarity in the context of European heritage : The cases of the European Solidarity Centre and Hambach Castle
2019
This article explores the politics of solidarity in the framework of constructing a common cultural heritage of the European Union. The politics of solidarity stems from the notion of solidarity embedded to European heritage. We use critical heritage studies as a theoretical approach that understands heritage as an inherently dissonant social construct, produced by various actors according to political, economic and social interests. The study analyses empirical data from the European Heritage Label (EHL), a flagship heritage action of the EU that communicates shared values and a sense of identification to European citizens. Our empirical data includes ethnographic observation as well as in…
Blocos/batucadas en los barrios obreros de Madrid. La percusión colectiva como cultura de clase
2019
Influenciados por los blocos afro y los movimientos antisistema europeos, los primeros blocos de tambores brasileños (batucadas) comienzan a formarse en Madrid en los inicios del milenio. Su continua presencia en las calles durante los años de la crisis y posteriormente en el 15M los ha convertido en un fenómeno cultural imprescindible en cualquier reivindicación popular progresista. Algunos de ellos, ubicados y vinculados a los movimientos vecinales y/o anticapitalistas de los barrios obreros de la capital, forman parte de la vida cotidiana de su entorno a través de su participación en sus reivindicaciones y fiestas. Con su música, entendida como herramienta de transformación social, contr…
Socio-spatial differentiation in transition: a preliminary comparative analysis of post-soviet St Petersburg and Riga
2020
Research into the socio-spatial dynamics in Central European cities is an important area of contemporary transition studies. Open issues in this domain range from defining a theoretical framework to data availability and methodological approaches. As to the former aspect, recent literature focuses on the hybrid nature of the post-socialist urban space, which underwent modernization in the conditions of globalization and economic liberalization; the earlier model of spatial development changed dramatically as a result. The multi-scalar and comparative approaches may shed new light on the complex patterns of urban socio-spatial differentiation and its post-Soviet dynamics. Growing regional so…
The transformation of the Ministries of Foreign Affairs in the Baltic countries
2021
This article analyses the transformation of the Ministries of Foreign Affairs (MFA) and the nature of changes in the Baltic countries (Estonia, Latvia, and Lithuania). By applying Brian Hocking’s a...
Digital Banking in Northern India: The Risks on Customer Satisfaction
2021
The widespread use of digital technologies and the current pandemic (COVID) have fueled the need and call for digital transformation in the banking sector. Although this has various benefits, it is a disruption to the norm to which a bank customer has to become accustomed. This variance means that customers would have to make some changes to their routine. This can constitute risks in terms of maintaining customer satisfaction at previous levels. These risks are associated with customer retention because a service or product needs to be aligned with customer expectations to avoid them switching to other service providers. Moreover, it can also have an effect on reputa- tion. Offering digita…
The influence of transformational and authentic leadership on the satisfaction of hotel customers in the Canary Islands
2019
Leadership provides a strategy to deal with intense competition and high customer expectations in the hotel industry. This paper analyses the ability of managers’ transformational and authentic leadership to predict customer satisfaction. A sample of 18,944 customers and managers of eight hotels in the Canary Islands was used for the analysis. The data were collected using the Multifactor Leadership Questionnaire-6s, the Authentic Leadership Questionnaire and ReviewPro management software. The data were analysed to confirm the ability of transformational and authentic leadership to predict overall customer satisfaction. The results indicate that the transformational subscales of idealised i…
Metabolic relation of cyanobacteria to aromatic compounds
2018
Cyanobacteria, also known as blue-green (micro)algae, are able to sustain many types of chemical stress because of metabolic adaptations that allow them to survive and successfully compete in a variety of ecosystems, including polluted ones. As photoautotrophic bacteria, these microorganisms synthesize aromatic amino acids, which are precursors for a large variety of substances that contain aromatic ring(s) and that are naturally formed in the cells of these organisms. Hence, the transformation of aromatic secondary metabolites by cyanobacteria is the result of the possession of a suitable “enzymatic apparatus” to carry out the biosynthesis of these compounds according to cellular requireme…
Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms
1992
Primary steps in the metabolism of caffeine and theophylline are cleavage of methyl groups and/or hydroxylation at position 8, mediated by cytochromes P450. V79 Chinese hamster cells genetically engineered for stable expression of single forms of rat cytochromes P450IA1, P450IA2 and P450IIBI and human P450IA2 and rat liver epithelial cells expressing murine P450IA2 were used to overcome problems arising in the proper allocation of metabolic pathways to specific isoforms by conventional techniques. These cell lines were exposed to caffeine and/or theophylline, and concentrations of metabolites formed in the medium were determined by HPLC. Caffeine was metabolized by human, rat and murine P45…
Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1.
1992
1. Chinese hamster V79-derived cell lines, stably expressing cytochromes P4501A1, 1A2, and 2B1 activities, were constructed by genetic engineering in continuation of our work to establish a battery of V79 derived cell lines designed to study the metabolism of xenobiotics. 2. Cell lines XEM1 and XEM2, expressing cytochrome P4501A1, were capable of the O-dealkylation of 7-ethoxycoumarin and the hydroxylation of benzo[a]pyrene. 3. Cell lines XEMd.MZ and XEMd.NH, expressing P4501A2, were shown to hydroxylate 17 beta-estradiol and 2-aminofluorene. 4. Cell line SD1, expressing cytochrome P4502B1, was able to hydroxylate testosterone stereo- and regio-specifically at the 16 alpha and 16 beta posit…
Kinetic experiments on the binding of metyrapone to liver microsomes
1969
Kinetic experiments on the inhibition of oxidative microsomal O- and N-demethylations by metyrapone (2-methyl-1, 2-bis(3-pyridyl)-l-propanone, Su 4885) were carried out using mouse liver microsomes as the enzyme source. The model substrates were p-nitroanisole and N-monomethyl-p-nitroaniline. It was shown that the inhibition is competitive. The K i for metyrapone is 0.42 × 10−4 M and for the reduced metabolite of metyrapone 1.15×10−4 M. Their spectral dissooiation constants as determined from difference spectra have almost the same values. From this it is concluded that the degree of inhibition is correlated to the amount of metyrapone bound to cytochrome P-450. Metyrapone does not seem to …