Search results for "TRANSFORMATION"
showing 10 items of 1634 documents
The telltale structures of epoxide hydrolases.
2003
Traditionally, epoxide hydrolases (EH) have been regarded as xenobiotic-metabolizing enzymes implicated in the detoxification of foreign compounds. They are known to play a key role in the control of potentially genotoxic epoxides that arise during metabolism of many lipophilic compounds. Although this is apparently the main function for the mammalian microsomal epoxide hydrolase (mEH), evidence is now accumulating that the mammalian soluble epoxide hydrolase (sEH), despite its proven role in xenobiotic metabolism, also has a central role in the formation and breakdown of physiological signaling molecules. In addition, a certain class of microbial epoxide hydrolases has recently been identi…
Valutazioni interscalari nel processo perequativo del PRG di Siracusa
2016
La questione abitativa è tornata ad essere cruciale per assicurare una maggiore equità sociale, aumentando la coesione sociale e riducendo le diseguaglianze all’interno dei sistemi metropolitani o territoriali che, nell’attuale congiuntura di grave crisi economica, devono comunque rispondere alle sfide globali di sviluppo, innovazione e sostenibilità. Questo studio si propone di costruire un sistema di conoscenze sulle condizioni di accesso alla casa a scala territoriale attraverso cui individuare le criticità locali dei problemi abitativi che potrebbero essere risolti attraverso i tradizionali strumenti di pianificazione o attraverso nuove pratiche di Social Housing che coinvolgono soggett…
High-pressure structural and elastic properties of Tl2O3
2014
The structural properties of Thallium (III) oxide (Tl2O3) have been studied both experimentally and theoretically under compression at room temperature. X-ray powder diffraction measurements up to 37.7 GPa have been complemented with ab initio total-energy calculations. The equation of state of Tl2O3 has been determined and compared to related compounds. It has been found experimentally that Tl2O3 remains in its initial cubic bixbyite-type structure up to 22.0 GPa. At this pressure, the onset of amorphization is observed, being the sample fully amorphous at 25.2 GPa. The sample retains the amorphous state after pressure release. To understand the pressure-induced amorphization process, we h…
First-order linear differential equations whose data are complex random variables: Probabilistic solution and stability analysis via densities
2022
[EN] Random initial value problems to non-homogeneous first-order linear differential equations with complex coefficients are probabilistically solved by computing the first probability density of the solution. For the sake of generality, coefficients and initial condition are assumed to be absolutely continuous complex random variables with an arbitrary joint probability density function. The probability of stability, as well as the density of the equilibrium point, are explicitly determined. The Random Variable Transformation technique is extensively utilized to conduct the overall analysis. Several examples are included to illustrate all the theoretical findings.
Singularity tracking for Camassa-Holm and Prandtl's equations
2006
In this paper we consider the phenomenon of singularity formation for the Camassa-Holm equation and for Prandtl's equations. We solve these equations using spectral methods. Then we track the singularity in the complex plane estimating the rate of decay of the Fourier spectrum. This method allows us to follow the process of the singularity formation as the singularity approaches the real axis.
Evidence of chloroethylene oxide being the reactive metabolite of vinyl chloride towards DNA: comparative studies with 2,2′ -dichloro-diethylether
1983
The roles of chloroethylene oxide (CEO) and chloroacetaldehyde (CAA) in carcinogenicity of vinyl chloride (VC) have been studied by comparing biological effects of VC exposure with those of 2,2'-dichlorodiethylether (bis(chloroethyl)ether, BCEE) as a metabolic precursor of CAA. Biological end-points investigated were covalent protein binding, nucleic acid (RNA and DNA) alkylation and the potency of the two chemicals to induce preneoplastic ATPase-deficient foci in rat liver. After exposure of rats to [1-14C]BCEE, BCEE derived radioactivity was bound to liver proteins. Analysis of hydrolysates of liver RNA and DNA gave no indication for the formation of either 7-N-(2-oxoethyl)guanine, 1,N6-e…
Exhalation of ethylene oxide by rats on exposure to ethylene.
1983
Abstract When rats are exposed to ethylene in a closed desiccator jar chamber, the rate of metabolic elimination of the compound is influenced by pretreatment with Aroclor 1254 (metabolism increased) and diethyldithiocarbamate (metabolism inhibited). Biotransformation of ethylene leads to ethylene oxide as reactive intermediate. This is exhaled and can be quantitated in the gas phase of the system.
A highly dynamic hot hydrothermal system in the subduction environment: Geochemistry and geochronology of jadeitite and associated rocks of the Sierr…
2021
A U-Pb zircon date of ~113 Ma revealed that a variety of jadeitites and related omphacitite, chloritite and albite-rich rocks from the subduction-related Sierra del Convento block-in-serpentinite-matrix mélange (eastern Cuba) formed nearly synchronously with MORB metabasite-derived anatectic trondhjemitic liquids at high-temperature and pressure in a hot subduction environment. Field, petrologic and geochemical data indicate hydrothermal/metasomatic processes triggered by juvenile fluids likely evolved from the crystallizing hydrous trondhjemitic melts. These fluids, variably mixed with sediment-derived fluids and channelized along fractures in the supra-slab mantle, precipitated relatively…
Les transformations de l'enseignement supérieur en France depuis 1966
1974
International audience
Advanced energetics of a Multiple Effects Evaporation (MEE) desalination plant
2010
This paper represents the Part I of a paper in two parts, aimed at proposing a 2nd principle and thermoeconomic analysis for a Multiple Effects Evaporation (MEE) process and discussing solutions for optimization and energy saving. After a brief analysis of the thermochemical fundamentals of desalination, the minimum theoretical work of separation is introduced to represent a reference condition for the assessment of plants' efficiency. A forward feed MEE configuration is then analysed, abandoning the conventional approach to “at overall plant-level”-analysis; a zooming strategy, based on focusing on the physical model of a generic stage (i.e. effect), is preferred to best recognize the marg…