Search results for "TRAS"

OTTIMIZZAZIONE DELLE PRESTAZIONE DEL SISTEMA DEI TRASPORTI TRAMITE L’ARMONIZZAZIONE INTERNAZIONALE DEGLI APPARATI DI SEGNALAZIONE

2012

Genetic determinants of ATR inhibitor sensitivity and resistance in Gastric Cancer

2019

Synthetic lethal approaches in identifying genetic determinants of drug response is a powerful method in selecting patents for targeted cancer therapies. Ataxia-Telangiectasia Mutated (ATM) and Rad3-related protein kinase (ATR) is a valuable target to inhibit the DNA damage repair (DDR) pathway, that has been shown to be particularly effective in cancer cells harbouring other DDR defects, including truncating mutations in ARID1A, found in the 20% of gastric cancer (GC) patients. Although ATR inhibitors (ATRi) are emerging as promising cancer therapies, resistance mechanisms inevitably arise from these drugs as monotherapy, emphasising the importance of identifying genetic determinants of re…

Augstas intensitātes intervālu slodzes ietekme uz enerģētisko metabolismu slodzes laikā un pēcslodzes atjaunošanās periodā jaunām sievietēm

2019

Augstas intensitātes intervālu slodzes ietekme uz enerģētisko metabolismu slodzes laikā un pēcslodzes atjaunošanās periodā jaunām sievietēm. Tiltiņa K., zinātniskais vadītājs Dr. biol., asoc. prof. Ozoliņa-Molla L. Maģistra darbs, 61 lapaspuse, 19 attēli, 15 tabulas, 47 literatūras avoti, 2 pielikumi. Latviešu valodā. Arvien biežāk kā efektīva metode taukaudu, it sevišķi viscerālo taukaudu, masas samazināšanai sabiedrībā tiek pielietots treniņu veids – augstas intensitātes intervālu treniņš (HIIT), kur augstas intensitātes (80 – 95% no maksimālās sirdsdarbības frekvences) intervāli mijas ar aktīvas atpūtas periodiem ar mērenu (40 – 60% no maksimālās sirdsdarbības frekvences) intensitāti. Pē…

Trasformazione e riuso dei vuoti urbani: quattro casi studio

2016

Il saggio indaga su contesti urbani consolidati che contengono tracce appartenenti a preesistenze industriali oggi in disuso, ma che costituiscono originali trame urbane da reinterpretare, riqualificare e riutilizzare in alternativa alle nuove espansioni. Il progetto della trasformazione/cambiamento diviene una metodologia d’intervento che richiede approcci, sensibilità e strumenti adeguati, che vanno dal controllo urbanistico a quello architettonico, dalla verifica tecnologica e strutturale a quella sociale e fruitiva. Sono presentate alcune ipotesi progettuali che illustrano come la valorizzazione delle aree industriali possa contribuire alla rigenerazione urbana di interi quartieri o por…

The “central dot sign” in acute epiploic appendagitis

2018

Epiploic appendagitis is the acute inflammation and infarction of epiploic appendages, commonly secondary to torsion. It is a great mimicker as its clinical manifestation may be similar to appendicitis, diverticulitis, or colitis. Focal abdominal pain, tenderness, and mild pyrexia are clinical features of the condition [1]. Epiploic appendages are pedunculated adipose structures which extend from the serosal surface of the colon, along the free taenia and taenia omentalis. They are abundant in the caecum and sigmoid colon and absent in the rectum

Intestinal tuberculosis in a child living in a country with a low incidence of tuberculosis : a case report

2014

Background: Relatively common in adults, intestinal tuberculosis is considered rare in children and adolescents. The protean manifestations of intestinal tuberculosis mean that the diagnosis is often delayed (sometimes even for years), thus leading to increased mortality and unnecessary surgery. The main diagnostic dilemma is to differentiate intestinal tuberculosis and Crohn’s disease because a misdiagnosis can have dramatic consequences. Case presentation: A 13-year-old Caucasian, Italian female adolescent attended the Emergency Department complaining of abdominal pain, a fever of up to 38°C, night sweats, diarrhea with blood in stool, and a weight loss of about three kilograms over the p…

Giant hepatocellular adenoma as cause of severe abdominal pain: a case report

2007

Abstract The authors describe the case of a large hepatocellular adenoma diagnosed in a 30-year old woman who came to us complaining of acute pain in the upper abdominal quadrants. The patient had been taking an oral contraceptive pill for the last ten years. We present the clinical features, the diagnostic work-up and the treatment prescribed.

Median arcuate ligament syndrome, a rare case of chronic abdominal pain

2018

The median arcuate ligament syndrome (MALS) is a rare disease characterized by abdominal pain caused by the external compression of the celiac artery by the median arcuate ligament. Surgical treatment is indicated, but given the non-specific symptoms, these patients are often hospitalized in the Departments of Internal Medicine where the diagnosis may be unknown. We present a case of MALS admitted to our Internal Medicine Division. An abdominal ultrasound in a woman with longstanding abdominal pain showed elevated celiac artery velocities during forced expiration. Computed tomography angiography (CTA) of the abdomen showed stenosis of the origin of the celiac artery and confirmed the diagno…

A rare case of acute idiopathic colocolic intussusception in an adult patient

2020

Abstract Adult intussusception is a rare condition that is frequently associated with malignancy and requires surgical approach. Symptoms are often non-specific and of subacute or chronic character. Therefore, computerized tomography (CT) scan is the most commonly used modality for identifying adult intussusception. A 51-year-old female presented with a 1-day history of increasing abdominal pain. Abdominal ultrasound and CT scan revealed intussusception. Intra-operatively, colocolic intussusception was present and laparoscopically reduced. A lead point was found neither intra-operatively nor in post-operative ileocolonoscopy and resection of involved bowel segments was not necessary.

Ultrasonography (US) in the assessment of pediatric non traumatic gastrointestinal emergencies

2013

AbstractBackgroundNon traumatic gastrointestinal emergencies in the children and neonatal patient is a dilemma for the radiologist in the emergencies room and they presenting characteristics ultrasound features on the longitudinal and axial axis. The most frequent emergencies are : appendicitis, intussusceptions, hypertrophic pyloric stenosis, volvulus due to intestinal malrotation. The aim of this article is to familiarize the reader with the US features.MethodsA retrospective analysis of 200 ultrasound examinations performed in neonatal and children patients with fever, abdominal pain, leukocytosis, vomiting and diarrhea were evaluated.ResultsOf 200 exame 50 cases of intussusceptions, 100…