Search results for "TRIF"

showing 10 items of 1419 documents

Intramolecular Cycloaddition Azomethine Ylides and α-(Trifluoromethyl)styrenes as Dipolarophiles

2019

chemistry.chemical_compoundTrifluoromethylchemistryIntramolecular forceOrganic ChemistryPhysical and Theoretical ChemistryMedicinal chemistryCycloadditionEuropean Journal of Organic Chemistry
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A new strategy for the synthesis of highly functionalised fluorinated compounds by reaction of lithium dianions of carboxylic acids with perfluoroket…

2005

The reaction of perfluoroketene dithioacetal with lithium dienediolates of carboxylic acids proceeds at the ω position probably through an addition to the π system followed by elimination of the vinylic fluoride. The preparative value of this reaction depends strongly on the reaction and work-up conditions. The overall process lead to highly functionalised synthons containing a trifluoromethyl group.

chemistry.chemical_compoundTrifluoromethylchemistryOrganic ChemistryDrug DiscoverySynthonchemistry.chemical_elementLithiumBiochemistryMedicinal chemistryFluorideTetrahedron
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ChemInform Abstract: Catalytic Enantioselective Conjugate Alkynylation of β-Aryl-β-trifluoromethyl Enones Constructing Propargylic All-Carbon Quatern…

2016

The enantioselective conjugate alkynylation of β-aryl-β-trifluoromethyl enones has been carried out using terminal alkynes and diethylzinc in the presence of 3,3′-bis(perfluorophenyl)BINOL as the chiral ligand to give the corresponding ketones bearing a trifluoromethylated propargylic quaternary stereocenter with fair to good enantioselectivities. Enones bearing a bulky 2-naphthyl attached to the carbonyl group provided the best enantioselectivities. The synthetic applicability of the resulting products has been demonstrated with their iodocyclization to form 4H-pyrans.

chemistry.chemical_compoundTrifluoromethylchemistryOrganocatalysisArylChiral ligandEnantioselective synthesisGeneral MedicineDiethylzincMedicinal chemistryStereocenterConjugateChemInform
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Innentitelbild: Synthesis and Application of β-Substituted Pauson-Khand Adducts: Trifluoromethyl as a Removable Steering Group (Angew. Chem. 20/2013)

2013

chemistry.chemical_compoundTrifluoromethylchemistryStereochemistryGeneral MedicineSteering groupAdductAngewandte Chemie
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Inside Cover: Synthesis and Application of β-Substituted Pauson-Khand Adducts: Trifluoromethyl as a Removable Steering Group (Angew. Chem. Int. Ed. 2…

2013

chemistry.chemical_compoundTrifluoromethylchemistryStereochemistryPauson–Khand reactionRegioselectivityCover (algebra)General ChemistrySteering groupCatalysisAdductAngewandte Chemie International Edition
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Homoleptic Pnictogen-Chalcogen Coordination Complexes

2012

The synthesis and structural characterization of dicationic selenium and tellurium analogues of the carbodiphosphorane and triphosphenium families of compounds are reported. These complexes, [Ch(dppe)][OTf](2) [Ch = Se, Te; dppe = 1,2-bis(diphenylphosphino)ethane; OTf = trifluoromethanesulfonate], are formed using [Ch](2+) reagents via a ligand-exchange protocol and represent extremely rare examples of homoleptic pnictogen → chalcogen coordination complexes. The corresponding arsenic compounds were also prepared, [Ch(dpAse)][OTf](2) [Ch = Se, Te; dpAse = 1,2-bis(diphenylarsino)ethane], exhibiting the first instance of an arsenic → chalcogen dative bond. The electronic structures of these un…

chemistry.chemical_elementPhotochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundChalcogenchemistryReagentPhysical and Theoretical ChemistryHomolepticTelluriumPnictogenTrifluoromethanesulfonateta116SeleniumArsenicInorganic Chemistry
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Chemical composition, antimicrobial and antioxidant activities of the essential oil of Italian Prangos trifida (Mill.) Herrnst. & Heyn

2022

In this work, the essential oil of the aerial parts of a not previously investigated accession of Prangos trifida (Mill.) Herrnst. & Heyn (Apiaceae), collected in Northern Italy, was analysed by GC/MS. Twenty-five compounds were identified, accounting for 91.30% of the total oil, which is characterised by a high content of monoterpene hydrocarbons (71.26%). The main constituents of the essential oil were cis-beta-ocimene (18.12%), alpha-phellandrene (12.14%), sylvestrene (11.32%), p-mentha-1,3,8-triene (9.56%) and alpha-pinene (8.85%). The essential oil of P. trifida showed a good antimicrobial activity directed above all against Gram-positive bacteria, and had an interesting antioxidan…

cis-β-ocimeneantioxidantOrganic ChemistryantimicrobialGC–MSPlant SciencePrangos trifidaBiochemistryessential oilAnalytical ChemistryApiaceae
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meso-Aryl-substituted free-base porphyrins: formation, structure and photostability of diprotonated species

2015

Susceptibility to interact with trifluoroacetic acid (TFA) of selected free-base porphyrins, including a novel lipophilic 3-n-pentadecyl(phenoxy)-ethoxy-phenyl-substituted porphyrin, and photostability of their diprotonated compounds was explored in benzene and N,N-dimethylformamide (DMF). Results have been discussed in terms of the commonly applied pK a -based procedure and confronted with a simple approach derived from experimentally-determined correlations reflecting the porphyrins affinity for TFA. Density functional theory (DFT) has proved the porphyrin moiety creates stable diprotonated species involving two TFA molecules, in which the fluorine atoms effectively contribute to the over…

computationChemistry(all)free-base porphyrinsprotonationProtonationProtonationphotobleaching010402 general chemistryPhotochemistryDFT01 natural sciencesFree-base porphyrinchemistry.chemical_compoundPolymer chemistryTrifluoroacetic acidlipophilic porphyrinsMoietyMoleculeReactivity (chemistry)Lipophilic porphyrinPhotobleaching010405 organic chemistryArylDFT computationFree baseGeneral ChemistryPorphyrin0104 chemical scienceschemistryResearch on Chemical Intermediates
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Density functional/molecular dynamics simulations of phase-change materials

2013

computer memory materialsrakennecrystallizationamorphoustiheysfunktionaaliteoriakiteytyminenphase-change materialsfaasimuutosmateriaalisemiconductormolecular dynamicsvitrificationchalcogenideatomic structureatomirakennepuolijohteetkalkogenidimolekyylidynamiikkacomputer simulationscrystallinesimulointimuistitdensity functional theory
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Crystal structure of diaqua[5,10,15,20-tetrakis(4-methoxyphenyl)porphyrinato-κ4N]iron(III) diaqua(18-crown-6)potassium bis(trifluoromethanesulfonate)…

2015

In the title compound, [FeIII(C48H36N4O2)(H2O)2][K(C12H24O6)(H2O)2](SO3CF3)2·2C12H24O6, the FeIIIatom is situated on an inversion centre and is octahedrally coordinated by four pyrrole N atoms of the deprotenated 5,10,15,20-tetrakis(4-methoxyphenyl)porphyrinate ligand and two water molecules. The average equatorial Fe—N(pyrrole) bond length [2.043 (6) Å] is consistent with a high-spin (S= 5/2) iron(III) metalloporphyrin derivative. The K+cation, which also lies on an inversion centre, is chelated by the six O atoms of one 18-crown-6 molecule and is additionally coordinated by two water molecules in a distorted hexagonal–bipyramidal geometry. In the crystal, the cations, anions and one non-c…

crystal structureCrystallographytrifluoromethanesulfonateHydrogen bondStereochemistryLigand18-Crown-6Methane sulfonateGeneral ChemistryCrystal structureCondensed Matter PhysicsMedicinal chemistryPorphyrinData ReportsBond lengthiron(III) complex saltchemistry.chemical_compoundchemistryQD901-999General Materials Sciencetri­fluoro­methane­sulfonateporphyrinPyrroleActa Crystallographica Section E Crystallographic Communications
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