Search results for "TRIPLE"
showing 10 items of 506 documents
Low-pressure-MOCVD LaMnO3±δ very thin films on YSZ (100) optimized for studies of the triple phase boundary
2000
Abstract This paper deals with the preparation of LaMnO 3± δ (LM) layers by low pressure-metal organic chemical vapor deposition (LP-MOCVD) using La(tmhd) 3 and Mn(acac) 3 as organometallic precursors. By thermogravimetric analysis, these precursors were found to be suitable for LP-MOCVD in a well-defined range of total pressure and temperature of sublimation. The activation energies of the sublimation process were found to be independent of the pressure within the appropriate range (0.06–3 kPa) and their values were 177 and 100.5 kJ mol −1 for La(tmhd) 3 and Mn(acac) 3 , respectively. LM layers of various thickness ranging between a few and a few hundred nanometers with a controlled La/Mn …
A study of electron transfer in Ru(dcbpy)2(NCS)2 sensitized nanocrystalline TiO2 and SnO2 films induced by red-wing excitation.
2008
Excited state dynamics and electron transfer from the Ru(dcbpy)2(NCS)2 (RuN3) sensitizer to semiconductor nanoparticles were studied using time-resolved femtosecond absorption spectroscopy. We found that excitation of the red wing of the absorption spectrum of the sensitizer populates the (3)MLCT state directly, both in solution and attached on semiconductor nanoparticle films. Electron injection is slowed down and becomes gradually less efficient as excitation moves towards red from the absorption maximum at 535 nm. At 675 nm the injection is non-exponential and characterized by 5, 30 and 180 ps time constants. The non-exponential electron injection observed is assigned to injection from a…
Sustainable Manufacturing as Mutual Competence Building
2015
In this chapter, Sustainable Manufacturing as MCB, Halvor Holtskog, Richard Ennals, and Hans Chr Garmann Johnsen argue how sustainable manufacturing can be seen as combining the traditional manufacturing management perspective with organisational development and participatory perspectives. The definition of Sustainable Business Systems is different from other uses of sustainability. The chapter tries to link arguments for business and for education. Arguably Working Life Research has an integrative role. One might ask: how can universities be seen as sustainable work systems, and how can they develop an account of empowerment?
Balancing Organisational Design Principles: A Pragmatic Scandinavian Approach to CSR
2016
One can argue that Scandinavian countries have much of the essence of CSR incorporated in their culture and society. We use Norway as an example for this argument, by looking at the development of work-life since the 50s. Further, we use one highly industrialised area, Raufoss, as further proof of our claim of the lack of separate popularity of CSR, as it is already covered in the context of society. However, this is not the same as saying that there are no challenges to this model. One of the most challenging topics is innovation: this should be socially responsible innovation. The Norwegian, social model can seem to promote stability, so that people and companies become risk averse.
Advanced Virgo Status
2015
Abstract The detection of a gravitational wave signal in September 2015 by LIGO interferometers, announced jointly by LIGO collaboration and Virgo collaboration in February 2016, opened a new era in Astrophysics and brought to the whole community a new way to look at - or “listen” to - the Universe. In this regard, the next big step was the joint observation with at least three detectors at the same time. This configuration provides a twofold benefit: it increases the signal-to-noise ratio of the events by means of triple coincidence and allows a narrower pinpointing of GW sources, and, in turn, the search for Electromagnetic counterparts to GW signals. Advanced Virgo (AdV) is the second ge…
Let-7d-5p miRNA shows oncogenic functions in triple negative breast cancer
2018
Triple negative breast cancer (TNBC) is a highly aggressive subtype of BC which lack of targeted therapies and is associated with poor prognosis. The presence of Cancer Stem Cells (CSCs) could be responsible for TNBC resistance to therapy, recurrence and metastasis, and might explain the difficult of its eradication. MiRNAs -a class of small non-coding RNAs- can modulate gene expression and their dysregulation may cause cancer formation. The let-7 family is dysregulated in various cancers and often its roles are unclear and of difficult interpretation. For example, let-7d can be over- or down-expressed and can act as tumor suppressor or oncogene. Here, we evaluated the expression profiles o…
Multiple reaction monitoring for identification and quantification of oligosaccharides in legumes using a triple quadrupole mass spectrometer.
2022
Raffinose family oligosaccharides are non-digestible compounds considered as dietary prebiotics with health-related properties. Hence, it is important to develop highly specific methods for their determination. An analytical method is developed in this study for oligosaccharide identification and quantification using liquid chromatography-tandem mass spectrometry equipped with a triple quadrupole analyser operating in Multiple Reaction Monitoring mode. Raffinose, stachyose and verbascose are separated in a 10-minute run and the method is validated over a broad concentration range, showing good linearity, accuracy, precision and high sensitivity. A low-cost, short eco-friendly procedure for …
Abstract A18: miR-9 and miR-200 regulate PDGFRβ-mediated endothelial differentiation of neoplastic cells in triple-negative breast cancer
2016
Abstract Tumor vascularization is a fundamental step in solid tumor progression and is orchestrated by different pathways of vasculogenesis. In malignant tumors, neoplastic cells can differentiate into endothelial-like cells acquiring the expression of endothelial markers (i.e. CD31 and CD34) and participating in the formation of vascular-like structures that functionally deliver oxygen and nutrients to the tumor site. We recently identified PDGFRβ as an important player of this process in triple negative breast cancer (TNBC). Interestingly, increasing evidence supported a connection between PDGFRβ and epithelial to mesenchymal transition (EMT), important step for the endothelial trans-diff…
Fasting renders immunotherapy effective against low-immunogenic breast cancer while reducing side effects
2022
Immunotherapy is improving the prognosis and survival of cancer patients, but despite encouraging out-comes in different cancers, the majority of tumors are resistant to it, and the immunotherapy combinations are often accompanied by severe side effects. Here, we show that a periodic fasting-mimicking diet (FMD) can act on the tumor microenvironment and increase the efficacy of immunotherapy (anti-PD-L1 and anti-OX40) against the poorly immunogenic triple-negative breast tumors (TNBCs) by expanding early exhausted effector T cells, switching the cancer metabolism from glycolytic to respiratory, and reducing collagen depo-sition. Furthermore, FMD reduces the occurrence of immune-related adve…
Latvijas augstskolu nozīme uzņēmējdarbības ekosistēmā
2015
Augstskolas ir galvenais uzņēmējdarbības ekosistēmas attīstības virzītājspēks. Tās izglīto gan topošos darba devējus – uzņēmējus, gan arī darba ņēmējus. Tās ir viens no trim spēlētājiem Triple Helix modelī kopā ar valsti un industriju. Triple Helix modelis, ko Eckovics ir radījis 1993. gadā, izvirza priekšnosacījumus sekmīgai šo trīs modeļa dalībnieku sadarbībai, lai virzītu valsts ekonomiku pretim attīstībai. Galvenokārt visās attīstītajās valstīs šis modelis ir ieviests un būtiski uzlabo sadarbību starp industriju, augstskolām un valsti, sekmējot uzņēmējarbības attīstību. Tomēr Latvijā šis modelis nav pietiekami ņemts vērā, realizējot gan izglītības, gan arī uzņēmējdarbības vides attīstīb…