Search results for "TRIZ"
showing 10 items of 343 documents
Identification and enrichment of thyroid cancer stem cells in anaplastic cell lines
2008
Limbal stem cells as a potential source of pancreatic beta cells
2009
BACKGROUND/RATIONAL Beta cell replacement therapy represents an alternative approach to conventional insulin regimen for the management of type 1 diabetes. Stem cells theoretically represent a suitable and renewable source of surrogate beta cells. Recently, it has been demonstrated that corneal epithelium contains stem cells in the basal layer of the limbus. Our aim was to isolate and characterize limbal stem cells (LSCs) from adult corneal-limbal biopsies, and to assess their capability to differentiate into insulin-producing cells. METHODS 2-3 mm2 biopsies were obtained from limbus and central cornea of four patients undergoing surgery for ocular diseases not involving conjuctive or corne…
No association between BRAFV660E and metalloproteinase activity in anaplastic thyroid cell lines
2008
Antitumor effect of aminobisphosphonates on anaplastic thyroid carcinoma cell lines.
2009
Designing an Innovative Face-Milling Cutter
2013
The paper consists in a research in the design of an innovative face-milling cutter, in terms of product lifecycle management (PLM), with the help from creative design methods, such as TRIZ. The model of the lifecycle management of the cutting tools was presented, emphasizing the functional analysis and creative design phase. Based on this analysis, a new constructive variant of the milling cutter was designed and simulated with finite element method, highlighting its advantages compared with classic construction variants.
Sheep habit during hand milking, and relations between the incorrect hand milking procedure and mammary health
2023
This study aimed: (1) to evaluate the relation between the incorrect hand milking and mammary health; (2) to test the hypothesis of the ewe habit in the workstation, of their choice, during the milking. Teat moisturization with foam milk collected from the milk tank represents a high-risk factor because potentially contain mastitis-causing bacteria previously released from affected ewes. Moreover, it was found that sheep are routinary animals by habit during hand milking.
One-Loop Two and Three-Point Functions
2015
In this chapter we present a few relevant calculations of one-loop, one and two-point (scalar, vector and tensor) functions. IR and UV divergences are extensively treated. One example of IR-pole cancellation is presented. The two and three-body phase space integrals in D dimensions, needed for the calculation of IR divergent cross sections are also given. Last, the usage of the generic parametrization ( 6.27) for non-integer powers of propagators (which appear when one needs to integrate over the four-momentum, logarithmic functions that depend on the four-momentum) is shown with a simple two-loop example. With the tools given here, the reader should find straightforward to construct any hi…
Poincaré inequalities and Steiner symmetrization
1996
A complete geometric characterization for a general Steiner symmetric domain Ω ⊂ Rn to satisfy the Poincare inequality with exponent p > n−1 is obtained and it is shown that this range of exponents is best possible. In the case where the Steiner symmetric domain is determined by revolving the graph of a Lipschitz continuous function, it is shown that the preceding characterization works for all p > 1 and furthermore for such domains a geometric characterization for a more general Sobolev–Poincare inequality to hold is given. Although the operation of Steiner symmetrization need not always preserve a Poincare inequality, a general class of domains is given for which Poincare inequalities are…
Selected lactic acid bacteria as a hurdle to the microbial spoilage of cheese: Application on a traditional raw ewes' milk cheese
2013
To evaluate the efficacy of lactic acid bacteria (LAB) to improve the hygienic safety of a traditional raw milk cheese, the raw ewes’ milk protected denomination of origin (PDO) Pecorino Siciliano cheese was used as a model system. Different Pecorino Siciliano curds and cheeses were used as sources of autochthonous LAB subsequently used as starter and non-starter LAB. These were screened for their acidification capacity and autolysis. Starter LAB showing the best performance were genotypically differentiated and identified: two strains of Lactococcus lactis subsp. lactis were selected. From the nonstarter LAB, Enterococcus faecalis, Lactococcus garvieae and Streptococcus macedonicus strains…
Geometry and quasisymmetric parametrization of Semmes spaces
2014
We consider decomposition spaces R/G that are manifold factors and admit defining sequences consisting of cubes-with-handles. Metrics on R/G constructed via modular embeddings of R/G into Euclidean spaces promote the controlled topology to a controlled geometry. The quasisymmetric parametrizability of the metric space R/G×R by R for any m ≥ 0 imposes quantitative topological constraints, in terms of the circulation and the growth of the cubes-with-handles, to the defining sequences for R/G. We give a necessary condition and a sufficient condition for the existence of parametrization. The necessary condition answers negatively a question of Heinonen and Semmes on quasisymmetric parametrizabi…