Search results for "Tact"
showing 10 items of 1313 documents
Prediction of the difficulty level in a standardized reading comprehension test : contributions from cognitive psychology and psychometrics
2013
Esta investigación busca identificar posibles variables predictoras del nivel de dificultad de los ítems de comprensión de lectura utilizados en una prueba psicométrica estandarizada para la admisión a una institución universitaria. Se propusieron varios posibles predictores del nivel de dificultad, a saber: densidad proposicional, negaciones, estructura sintáctica, dificultad del vocabulario, presencia elementos de realce (palabras resaltadas tipográficamente), abstracción del ítem y grado de similitud entre opción correcta y texto relevante para resolver el ítem. Mediante el Modelo Logístico Lineal de Rasgo Latente se encontró que la cantidad de proposiciones, la estructura sintáctica y, …
Advances in Design, Simulation and Manufacturing IV
2021
This book reports on topics at the interface between mechanical and chemical engineering, emphasizing design, simulation, and manufacturing. Specifically, it covers recent developments in the mechanics of solids and structures, numerical simulation of coupled problems, including fatigue, fluid behavior, particle movement, pressure distribution. Further, it reports on developments in chemical process technology, heat and mass transfer, energy-efficient technologies, and industrial ecology. Based on the 4th International Conference on Design, Simulation, Manufacturing: The Innovation Exchange (DSMIE-2021), held on June 8-11, 2021, in Lviv, Ukraine, this second volume of a 2-volume set provide…
Some new Hadamard designs with 79 points admitting automorphisms of order 13 and 19
2001
Abstract We have proved that there exists at least 2091 mutually nonisomorphic symmetric (79,39,19)-designs. In particular, 1896 of them admit an action of the nonabelian group of order 57, and an additional 194 an action of the nonabelian group of order 39.
Hot Impression Die Forging Process: An Approach to Flash Design for Tool Life Improvement
2005
In impression die forging the role of the flash geometry is fundamental since a proper design of the flash land strongly influences both the complete die filling and the die wear (i.e. the die life and the related costs). In this paper an integrated approach between numerical simulations and statistical tools was developed with the aim to optimize flash thickness in order to reduce die wear and to minimize material wasting. As wear is regarded, an analytical model depending on sliding velocity, temperature, die hardness and contact pressure was utilized during the numerical simulations of the process in order to reach a wear evaluation for different values of the flash design variables. Thu…
The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells
2006
Disruption of cell proliferation control by polycyclic aromatic hydrocarbons (PAHs) may contribute to their carcinogenicity. We investigated role of the aryl hydrocarbon receptor (AhR) in disruption of contact inhibition in rat liver epithelial WB-F344 'stem-like' cells, induced by the weakly mutagenic benz[a]anthracene (BaA), benzo[b]fluoranthene (BbF) and by the strongly mutagenic benzo[a]pyrene (BaP). There were significant differences between the effects of BaA and BbF, and those of the strongly genotoxic BaP. Both BaA and BbF increased percentage of cells entering S-phase and cell numbers, associated with an increased expression of Cyclin A and Cyclin A/cdk2 complex activity. Their eff…
Contact Sensitizers Specifically Increase MHC Class II Expression on Murine Immature Dendritic Cells
2000
Contact sensitivity is a T-cell-mediated immune disease that can occur when low-molecular-weight chemicals penetrate the skin. In vivo topical application of chemical sensitizers results in morphological modification of Langerhans cells (LC). Moreover, within 18 h, LC increase their major histocompatibility complex (MHC) class II antigens expression and migrate to lymph nodes where they present the sensitizer to T lymphocytes. We wanted to determine if such an effect could also be observed in vitro. However, because of the high genetic diversity encountered in humans, assays were performed with dendritic cells (DC) obtained from a Balb/c mouse strain. The capacity of a strong sensitizer, DN…
Healthy design and urban planning strategies, actions, and policy to achieve salutogenic cities
2018
Starting from a previous experience carried out by the working group “Building and Environmental Hygiene” of the Italian Society of Hygiene and Preventive Medicine (SItI), the aim of the present work is to define new strategic goals for achieving a “Healthy and Salutogenic City”, which will be useful to designers, local governments and public bodies, policy makers, and all professionals working at local health agencies. Ten key points have been formulated: 1. climate change and management of adverse weather events; 2. land consumption, sprawl, and shrinking cities; 3. tactical urbanism and urban resilience; 4. urban comfort, safety, and security perception; 5. strengths and weaknesses of ur…
Interactive simulation of one-dimensional flexible parts
2006
Computer simulations play an ever growing role for the development of automotive products. Assembly simulation, as well as many other processes, are used systematically even before the first physical prototype of a vehicle is built in order to check whether particular components can be assembled easily or whether another part is in the way. Usually, this kind of simulation is limited to rigid bodies. However, a vehicle contains a multitude of flexible parts of various types: cables, hoses, carpets, seat surfaces, insulations, weatherstrips... Since most of the problems using these simulations concern one-dimensional components and since an intuitive tool for cable routing is still needed, w…
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules.
2008
Central nervous system myelination requires the synthesis of large amounts of myelin basic protein (MBP) at the axon–glia contact site. MBP messenger RNA (mRNA) is transported in RNA granules to oligodendroglial processes in a translationally silenced state. This process is regulated by the trans-acting factor heterogeneous nuclear ribonucleoprotein (hnRNP) A2 binding to the cis-acting A2 response element (A2RE). Release of this repression of MBP mRNA translation is thus essential for myelination. Mice deficient in the Src family tyrosine kinase Fyn are hypomyelinated and contain reduced levels of MBP. Here, we identify hnRNP A2 as a target of activated Fyn in oligodendrocytes. We show that…
Universal transport dynamics in a quenched tunnel-coupled Luttinger liquid
2016
The transport dynamics of a quenched Luttinger liquid tunnel-coupled to a fermionic reservoir is investigated. In the transient dynamics, we show that for a sudden quench of the electron interaction universal power-law decay in time of the tunneling current occurs, ascribed to the presence of entangled compound excitations created by the quench. In sharp contrast to the usual non universal power-law behavior of a zero-temperature non-quenched Luttinger liquid, the steady state tunneling current is ohmic and can be explained in terms of an effective quench-activated heating of the system. Our study unveils an unconventional dynamics for a quenched Luttinger liquid that could be identified in…