Search results for "Technology"
showing 10 items of 30343 documents
On the exploration of mobile technology acceptance among law enforcement officers using structural equation modelling (SEM) : a multi-group analysis …
2012
Excitation Transfer Engineering in Ce-Doped Oxide Crystalline Scintillators by Codoping with Alkali-Earth Ions
2018
This work has been supported by the European Social Fund Measure No. 09.3.3-LMT-K-712 activity Improvement of Researchers Qualification by Implementing the World-Class R&D Projects, and by grant #14.W03.31.0004 of the Russian Federation Government. Authors are grateful to CERN Crystal Clear Collaboration and COST Action TD1401 "Fast Advanced Scintillator Timing (FAST)" for support of collaboration.
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
2011
International audience; So far, no common environmental and/or phenotypic factor has been associated with melanoma and renal cell carcinoma (RCC). The known risk factors for melanoma include sun exposure, pigmentation and nevus phenotypes; risk factors associated with RCC include smoking, obesity and hypertension. A recent study of coexisting melanoma and RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia-associated transcription factor (MITF) has been proposed to act as a melanoma oncogene; it also stimulates the transcription of hypoxia inducible factor (HIF1A), the pathway of which is targeted by kidney canc…
A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.
2011
International audience; Buchnera aphidicola is an obligate symbiotic bacterium that sustains the physiology of aphids by complementing their exclusive phloem sap diet. In this study, we reappraised the transport function of different Buchnera strains, from the aphids Acyrthosiphon pisum, Schizaphis graminum, Baizongia pistaciae and Cinara cedri, using the re-annotation of their transmembrane proteins coupled with an exploration of their metabolic networks. Although metabolic analyses revealed high interdependencies between the host and the bacteria, we demonstrate here that transport in Buchnera is assured by low transporter diversity, when compared to free-living bacteria, being mostly bas…
Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy
2020
The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material.
Multilevel Latent Profile Analysis With Covariates : Identifying Job Characteristics Profiles in Hierarchical Data as an Example
2018
Latent profile analysis (LPA) is a person-centered method commonly used in organizational research to identify homogeneous subpopulations of employees within a heterogeneous population. However, in the case of nested data structures, such as employees nested in work departments, multilevel techniques are needed. Multilevel LPA (MLPA) enables adequate modeling of subpopulations in hierarchical data sets. MLPA enables investigation of variability in the proportions of Level 1 profiles across Level 2 units, and of Level 2 latent classes based on the proportions of Level 1 latent profiles and Level 1 ratings, and the extent to which covariates drawn from the different hierarchical levels of th…
Public note-taking on a digital platform as a workplace practice
2023
Unlike traditional note-taking with pen and paper, in which the note-taking process is only partially accessible to the co-participants, note-taking in the digitalized workplace may be done publicly, so that both the content of notes and the process of writing them are observable to the co-participants. Using multimodally oriented conversation analysis, this study focused on public note-taking in interaction sequences where the facilitator of a workplace project records the results of a workshop discussion on a digital platform. The analysis revealed that while the facilitator was entitled to decide which portions of talk are recorded, the affordances of digital technology, its publicness …
Single-mode Bragg gratings in tapered few-modes and multimode fibers
2019
We propose the implementation of fiber Bragg gratings in tapered few-mode and multimode fibers to accomplish single-mode operation by reducing the core diameter, while preserving the core-cladding structure. The gratings present a single reflection band, and the device shows low insertion losses after the taper fabrication and the fiber Bragg gratings inscription. The excitation of high-order odd modes in the core of the fiber has been identified as the main loss mechanism; it can be prevented by means of symmetric illumination of the fibers. We also demonstrate the excitation of high-order cladding modes (cladding-air modes) along the taper transitions; these modes can be removed without a…
Web social et multimédia : propriétés d'une relation symbiotique
2011
International audience; Les notions inhérentes aux principes du web social placent les contenus multimédias au cÉur de nouvelles pratiques communicationnelles. Les relations entre les nouveaux espaces de médiation ouverts par le web 2.0 et l'univers du multimédia ne s'inscrivent pas simplement dans un rapport linéaire et séquentiel de transfert d'innovations mais procèdent davantage d'une relation symbiotique aux bénéfices multiples. Dans une première partie nous mettrons en exergue les spécificités de ces relations puis nous questionnerons les nouveaux usages et les nouvelles pratiques qu'elles induisent. Dans une seconde partie, nous présenterons un ensemble de résultats obtenus suite à u…
Informasjonsflyt ved mottak og respons på trygghetsalarmer : en casestudie for å undersøke hvilken betydning tilgang på informasjon og informasjonsfl…
2016
Masteroppgave i helse- og sosialinformatikk- Universitetet i Agder, 2016 The theme of this study is security alarms and information flow. The background for the study is estimates regarding an upcoming growing number of security alarms in municipal healthcare services, recommendations on the transition from analogue to digital security alarms, and reports on the current organization of the safety alarms of varying quality and low efficiency (Frantzen, 2014; Fensli, 2015 Kvernland-Berg, 2014). Purpose The aim of this study was to find what importance access to information and information flow had in the working process with security alarms for a future-oriented health services. Method The su…