Search results for "Terpene"

showing 10 items of 816 documents

Photochemical Approaches to the Bilobalide Core

2017

Bilobalide is a tetracyclic sesquiterpene containing three contiguous γ-lactone rings and an unusual tert-butyl group, which is found in the leaves of the ginkgo tree (Ginkgo biloba). Three different photochemical approaches towards bilobalide's unique skeleton are presented. A meta photocycloaddition, a [2 + 2] photocycloaddition, and a Paterno–Buchi-reaction were chosen as the respective key steps.

biology010405 organic chemistryChemistryGinkgo bilobaStereochemistryGinkgoOrganic ChemistryTotal synthesis010402 general chemistryPhotochemistrybiology.organism_classificationSesquiterpene01 natural sciences0104 chemical scienceschemistry.chemical_compoundBilobalideOrganic chemistryPhysical and Theoretical ChemistryEuropean Journal of Organic Chemistry
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Xanthones and sesquiterpene derivatives from a marine-derived fungus Scopulariopsis sp.

2016

Abstract Two new xanthone derivatives, 12-dimethoxypinselin ( 1 ) and 12- O -acetyl-AGI-B4 ( 2 ), as well as two new phenolic bisabolane-type sesquiterpenes, 11,12-dihydroxysydonic acid ( 15 ) and 1-hydroxyboivinianic acid ( 16 ), together with one new alkaloid, scopulamide ( 21 ) and one new α-pyrone derivative, scopupyrone ( 26 ), in addition to twenty-three known compounds ( 3 – 14 , 17 – 20 , 22 – 25 , 27 – 29 ) were isolated from solid rice cultures of the marine-derived fungus Scopulariopsis sp. obtained from the Red Sea hard coral Stylophora sp. All compounds were unambiguously identified through extensive NMR spectroscopic analyses, and by comparison with the literature. Marfey's re…

biology010405 organic chemistryChemistryStereochemistryMouse LymphomaAlkaloidOrganic ChemistryAbsolute configurationFungusbiology.organism_classificationSesquiterpene01 natural sciencesBiochemistry0104 chemical sciencesXanthone Derivatives010404 medicinal & biomolecular chemistrychemistry.chemical_compoundTermészettudományokDrug DiscoveryXanthoneScopulariopsisKémiai tudományokTetrahedron
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New oxygenated eudesmanolides from artemisia herba-alba

1990

Abstract The aerial parts of Artemisia herba-alba Asso subsp.valentina Lam. (Asteraceae) yielded the new eudesmanolides 1-11 and the new sesquiterpene-monoterpene adducts 12-13. The absolute configuration of compound 6 was confirmed with the aid of X-ray diffraction analysis. Some aspects of the thermal and photochemical reactivity of 2,4-cyclohexadienones are discussed.

biologyArtemisia herba-albaStereochemistryChemistryMonoterpeneOrganic ChemistryAbsolute configurationAsteraceaebiology.organism_classificationSesquiterpeneBiochemistrychemistry.chemical_compoundDrug DiscoveryArtemisiaOrganic chemistryPhotochemical reactivityThermal reactionTetrahedron
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New umbelliferone sesquiterpene ethers from roots ofLigularia persica

1991

An extract of roots of Ligularia persica yielded thirteen umbelliferone sesquiterpene ethers, among them the new ones ligupersin A (11) and ligupersin B (13).

biologyBicyclic moleculeStereochemistryLigulariaOrganic ChemistryEtherNuclear magnetic resonance spectroscopySesquiterpenebiology.organism_classificationUmbelliferoneCoumarinchemistry.chemical_compoundchemistryOrganic chemistryPhysical and Theoretical ChemistryLiebigs Annalen der Chemie
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Triterpenoid saponins from Polycarpaea corymbosa Lamk. var. eriantha Hochst.

2013

Abstract Four triterpenoid saponins (1–4) were isolated from Polycarpaea corymbosa Lamk. var. eriantha Hochst along with the known apoanagallosaponin IV (5). Their structures were elucidated by spectroscopic data analysis. Among the compounds 1, 3–5 which were evaluated for their cytotoxicity against three tumor cell lines (SW480, DU145 and EMT6), compound 1 exhibited cytotoxicity with IC50 values ranging from 4.61 to 22.61 μM, which was greater than that of etoposide. Compound 2 was tested only against SW480 and a cardiomyoblast cell line (H9c2), and was inactive.

biologyChemistryCaryophyllaceaeTumor cellsCaryophyllaceaePlant ScienceGeneral MedicineHorticultureSaponinsbiology.organism_classificationBiochemistryAntineoplastic Agents PhytogenicTriterpenesInhibitory Concentration 50TriterpenoidDU145Cell Line TumorPolycarpaea corymbosaBotanyIc50 valuesHumansCytotoxicityMolecular BiologyPhytochemistry
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A germacrane derivative from Pallenis spinosa

1991

Abstract Extraction of aerial parts of Pallenis spinosa and chromatographic separation have yielded a new germacrane derivative and the known sesquiterpenes shiromool and α-cadinol.

biologyChemistryExtraction (chemistry)Pallenis spinosaPlant ScienceGeneral MedicineHorticulturebiology.organism_classificationSesquiterpeneBiochemistryChromatographic separationchemistry.chemical_compoundInuleaeMoleculeOrganic chemistryMolecular BiologyDerivative (chemistry)Phytochemistry
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Germacrane derivatives from Santolina chamaecyparissus

1991

Abstract The aerial parts of Santolina chamaecyparissus subsp. squarrosa yieleded five new germacrane derivatives and a known eudesmane dialcohol.

biologyChemistryStereochemistryPlant ScienceGeneral MedicineHorticulturebiology.organism_classificationSesquiterpeneBiochemistrySantolina chamaecyparissuschemistry.chemical_compoundAnthemideaeOrganic chemistryMolecular BiologyPhytochemistry
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Diterpenes from Euphorbia segetalis

1998

Numerous new diterpenes including several with new skeletons have been obtained from Euphorbia segetalis.

biologyEuphorbiaceaePlant ScienceGeneral MedicineHorticulturebiology.organism_classificationBiochemistryLabdanechemistry.chemical_compoundchemistryEuphorbia segetalisBotanyDiterpeneMolecular BiologyPhytochemistry
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Volatile components ofCentaurea cineraria L. subsp.umbrosa (Lacaita) Pign. andCentaurea napifolia L. (Asteraceae), two species growing wild in Sicily

2003

The volatile components of the flowerheads of Centaurea cineraria L. subsp. umbrosa (Lacaita) Pign. and Centaurea napifolia L. were obtained by hydrodistillation and identified by GC and GC-MS. Altogether 55 components were identified, mostly sesquiterpenes and hydrocarbons. Copyright © 2003 John Wiley & Sons, Ltd.

biologyFlorGeneral ChemistryAsteraceaebiology.organism_classificationSesquiterpeneTerpenoidlaw.inventionchemistry.chemical_compoundchemistryCentaurealawBotanyCentaurea cinerariaEssential oilFood ScienceAntibacterial agentFlavour and Fragrance Journal
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Composition of the essential oil fromflowerheads ofChrysanthemum coronarium L.(Asteraceae) growing wild in Southern Italy

2004

The essential oils from the aerial parts of Chrysanthemum coronarium L. (Asteraceae) growing wild in two different localities of Southern Italy, Lascari (L) and Palinuro (P), were obtained by hydrodistillation in a 0.13-0.16% yield. The oils were analysed by GC and GC-MS; 68 constituents, amounting to 89.0% of the oil (L), and 43 constituents, amounting to 91.6% of the oil (P), were identified. The trans-spiroketal-enol ether 2-(2,4- hexadiynylidene)-1,6-dioxaspiro(4,4)non-3-ene (trans-tonghaosu) with chrysanthenyl and lyratyl esters and camphor were the main components of the oils. Copyright © 2004 John Wiley & Sons, Ltd.

biologyGeneral ChemistryAsteraceaebiology.organism_classificationSesquiterpeneTerpenoidlaw.inventionSteam distillationCamphorchemistry.chemical_compoundchemistrylawAnthemideaeBotanyChrysanthenoneEssential oilFood ScienceFlavour and Fragrance Journal
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