Search results for "Terpenes"

showing 10 items of 470 documents

Polar organic marker compounds in PM2.5 aerosol from a mixed forest site in western Germany

2008

The molecular composition of PM2.5 (particulate matter with an aerodynamic diameter2.5 microm) aerosol samples collected during a very warm and dry 2003 summer period at a mixed forest site in Jülich, Germany, was determined by gas chromatography/mass spectrometry in an effort to evaluate photooxidation products of biogenic volatile organic compounds (BVOCs) and other markers for aerosol source characterization. Six major classes of compounds represented by twenty-four individual organic species were identified and measured, comprising tracers for biomass combustion, short-chain acids, fatty acids, sugars/sugar alcohols, and tracers for the photooxidation of isoprene and alpha-/beta-pinene.…

Environmental EngineeringHealth Toxicology and MutagenesisCarbohydratescomplex mixturesGas Chromatography-Mass SpectrometryTreesBridged Bicyclo Compoundschemistry.chemical_compoundHemiterpenesGermanyPentanesButadienesEnvironmental ChemistryVolatile organic compoundBiomassOrganic ChemicalsChemical compositionBicyclic MonoterpenesAerosolschemistry.chemical_classificationPhotolysisChemistryPharmacology. TherapyLevoglucosanFatty AcidsPublic Health Environmental and Occupational HealthGeneral MedicineGeneral ChemistryParticulatesPollutionAerosolChemistryHydrocarbonPyrogallolEnvironmental chemistryMonoterpenesParticulate MatterAcids AcyclicMalic acidVolatilizationOxidation-ReductionChemosphere
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Two new biologically active triterpenoidal saponins acylated with salicylic acid from Albizia adianthifolia

2003

International audience; Two new oleanane-type triterpene saponins, adianthifoliosides A (1) and B (2), were isolated from a 95% ethanolic extract of roots of Albizia adianthifolia. Their structures were elucidated mainly by using a combination of 600 MHz 1D and 2D NMR techniques (COSY, NOESY, TOCSY, HSQC, and HMBC) and by FABMS and HRESIMS. Compounds 1 and 2 were characterized as glycosides of acacic acid acylated by an o-hydroxybenzoyl unit. The crude saponin mixture (CSM), compounds 1 and 2 together with 3 and 4 (prosapogenins obtained from the mild alkaline hydrolysate of the CSM), were evaluated for immunomodulatory activity on the Jurkat T cell line and for hemolytic property against s…

ErythrocytesStereochemistrySaponinPharmaceutical ScienceAlbizziaPharmacognosy01 natural sciencesHemolysisPlant Roots[ CHIM ] Chemical SciencesHydrolysateAnalytical Chemistry[ SDV.EE ] Life Sciences [q-bio]/Ecology environmentJurkat CellsTriterpeneAdjuvants ImmunologicDrug DiscoveryAnimalsHumans[CHIM]Chemical SciencesOleanolic AcidNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classification[SDV.EE]Life Sciences [q-bio]/Ecology environmentPlants MedicinalSheepbiologyDose-Response Relationship DrugMolecular Structure010405 organic chemistryOrganic ChemistryGlycosideBiological activityAcetylationSaponinsbiology.organism_classificationAntineoplastic Agents PhytogenicTerpenoidTriterpenes0104 chemical sciences010404 medicinal & biomolecular chemistryCote d'IvoireComplementary and alternative medicinechemistryMolecular MedicineSalicylic AcidAlbizia adianthifolia
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Chemical constituents and antiproliferative activity of Euphorbia bivonae

2011

Euphorbia is a genus of plants belonging to the family Euphorbiaceae, consisting of about 2160 species. This family occurs mainly in the Indo-Malayan region and tropical America. Euphorbia also has many species in non-tropical areas such as the Mediterranean area, the Middle East, South Africa, and southern USA. Phytochemical studies of species from the genus Euphorbia report the presence of skin-irritating and tumor-promoting diterpenoids, several macrocyclic diterpenoids with antibacterial, anticancer, PGE2-inhibitory, antifeedant, anti-HIV, and analgesic activities. Some of the Euphorbiaceae species are used in folk medicine for the treatment of skin diseases, gonorrhea, migraines, intes…

Euphorbia bivonaeChemistryChemical constituentsEuphorbia bivonae coumarins triterpenes antiproliferative activityOrganic chemistryPlant ScienceGeneral ChemistrySettore CHIM/08 - Chimica FarmaceuticaGeneral Biochemistry Genetics and Molecular BiologyChemistry of Natural Compounds
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Hastifolins A-G, antefeedant neo-clerodane diterpenoids from Scutellaria hastifolia

2010

From the aerial parts of Scutellaria hastifolia, family Lamiaceae (Labiatae), seven neo-clerodane diterpenoids (hastifolins A-G) were isolated. The products are similar to the known scuteparvin and are characterized by being trans-cinnamoyl derivatives. Structures and stereochemistry were determined by intensive NMR investigation. Six of the products form three pairs of epimers at C-13. Hastifolins A-C showed significant antifeedant activity.

Family LamiaceaeStereochemistryScutellariaChemical structurePlant ScienceHorticultureSpodopteraBiochemistryDiterpenes Clerodanechemistry.chemical_compoundFeeding behaviorAnimalsMolecular BiologyNuclear Magnetic Resonance BiomolecularbiologyMolecular StructureGeneral MedicineFeeding BehaviorSettore CHIM/06 - Chimica Organicabiology.organism_classificationTerpenoidchemistryLarvaScutellariaLamiaceaeEpimerDiterpeneScutellaria hastifolia Lamiaceae diterpenes neo-clerodanes epimers antifeedant
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Capillary Liquid Chromatography for the Determination of Terpenes in Botanical Dietary Supplements

2021

Dietary supplements of botanical origin are increasingly consumed due to their content of plant constituents with potential benefits on health and wellness. Among those constituents, terpenes are gaining attention because of their diverse biological activities (anti-inflammatory, antibacterial, geroprotective, and others). While most of the existing analytical methods have focused on establishing the terpenic fingerprint of some plants, typically by gas chromatography, methods capable of quantifying representative terpenes in herbal preparations and dietary supplements with combined high sensitivity and precision, simplicity, and high throughput are still necessary. In this study, we have e…

Farnesenenatural productsPharmaceutical ScienceOrange (colour)01 natural sciencesArticleTerpenedietary supplementschemistry.chemical_compoundPharmacy and materia medica0404 agricultural biotechnologyLinaloolDrug DiscoveryLimoneneChromatography010401 analytical chemistryR04 agricultural and veterinary sciencesplant materials040401 food sciencecapillary liquid chromatography0104 chemical sciencesRS1-441chemistryMyrceneGreen coffee extractMedicineMolecular MedicineGas chromatographyterpenesPharmaceuticals
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Anti-inflammatory Effects of South American Tanacetum vulgare

1998

Abstract In recent years the role of phenolic compounds and sesquiterpene lactones, particularly parthenolide, in the anti-migraine and anti-inflammatory effects of Tanacetum parthenium (Asteraceae) has attracted much attention. However, the closely-related cosmopolitan species T. vulgare has remained outside the mainstream of research in this field. After treating the aerial parts of T. vulgare with dichloromethane and methanol, and applying conventional column and thin-layer chromatographic techniques, it was possible to isolate from the moderately lipophilic fractions the principles responsible for the anti-inflammatory activity of this plant against the mouse-ear oedema induced by 12-O-…

FlavonoidAnti-Inflammatory AgentsPharmaceutical SciencePharmacognosyBiologySesquiterpeneChrysoeriolFlavonesMiceStructure-Activity Relationshipchemistry.chemical_compoundTanacetum partheniumBotanyAnimalsEdemaParthenolideFlavonoidsPharmacologychemistry.chemical_classificationTraditional medicinePlant ExtractsSouth AmericaDiosmetinchemistryCarcinogensTetradecanoylphorbol AcetateFemaleSesquiterpenesJournal of Pharmacy and Pharmacology
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Secondary metabolites from Pinus mugo Turra subsp. mugo growing in the Majella National Park (Central Apennines, Italy).

2013

In this study, we examined the composition regarding secondary metabolites of P. mugo Turra ssp. mugo growing in the protected area of Majella National Park, which is the southernmost station of the habitat of this species. Both the nonpolar and polar fractions were considered. In particular, the essential-oil composition showed a high variety of compounds, and 109 compounds were detected, and 101 were identified, among which abietane-type compounds have a taxonomic relevance. Abietanes were also isolated from the polar fraction, together with an acylated flavonol and a remarkably high amount of shikimic acid.

FlavonolsBioengineeringBiochemistryEssential oilPinus mugoBotanyOils Volatileessential oilsMolecular BiologyEcosystembiologyNational parkChemistryPinus mugoflavonols; diterpenes; essential oils; abietanes; pinus mugoGeneral ChemistryGeneral MedicineSettore CHIM/06 - Chimica Organicabiology.organism_classificationPinusPinus <genus>ItalyAbietanesMolecular MedicineAbietaneDiterpenesDiterpeneFlavonolChemistrybiodiversity
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Phytochemical study of Cistus libanotis L.

2015

n continuation of our ongoing study on Mediterranean Flora, we focused the attention on Cistus genus. These plants possess interesting secondary metabolites and are used in many fields, principally in perfumery and more recently as raw material for food supplements (botanicals). n this article, we report the phytochemical analysis of Cistus libanotis L. from Tunisia. Among the diterpenes, labdane compounds resulted absent, in favour of two clerodanes, one of that never reported in Cistus sp. The main representative compounds were found to be several flavonoids with various grades of O-methylation. Other interesting components were two cinnamic esters of borneol, reported here for the first …

FloraTunisiaCistuPlant ScienceCistus libanotisBiochemistryditerpeneBorneolDiterpenes ClerodanePlant ExtractAnalytical ChemistryLabdanechemistry.chemical_compoundGenusCistusBotanycistus libanotis; clerodane; diterpene; phenolsphenolbiologyMolecular StructurePlant ExtractsOrganic ChemistryCistusbiology.organism_classificationPlant LeaveschemistryPhytochemicalclerodaneCistus libanotiDiterpenePlant Leave
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Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.

2018

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190540 También participan en la elaboración de este artículo científico: Aracely Calatayud-Pascual, Alicia López-Castellano, Elena P. Albelda, Enrique García-España, Luis Martí-Bonmatí, Juan C. Frias y M. Teresa Albelda. Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.

Fluorescence-lifetime imaging microscopyPathologylcsh:MedicineAngiogenesis Inhibitors02 engineering and technology030204 cardiovascular system & hematologyVascular MedicineBiochemistryArteriosclerosis - Chemotherapy.Diagnostic RadiologyAteroesclerosis - Farmacoterapia.MiceWhite Blood Cells0302 clinical medicineAnimal CellsArteriosclerosis - Farmacoterapia.Medicine and Health SciencesArteries - Diseases - Treatment.Nanotechnologylcsh:ScienceAortaPhospholipidsmedia_commonMice KnockoutLiposomeDrug CarriersMultidisciplinarymedicine.diagnostic_testRadiology and Imaging021001 nanoscience & nanotechnologyMagnetic Resonance ImagingLipidsFatty Acids UnsaturatedEngineering and Technologymedicine.symptomCellular Structures and OrganellesCellular TypesAnatomy0210 nano-technologySesquiterpenesResearch ArticleDrugmedicine.medical_specialtyImaging Techniquesmedia_common.quotation_subjectImmune CellsImmunologyLiposomes.Research and Analysis MethodsLiposomas.Lesion03 medical and health sciencesText miningApolipoproteins ECyclohexanesDiagnostic Medicinemedicine.arteryFluorescence ImagingmedicineAnimalsArterias - Enfermedades - Tratamiento.VesiclesAortaBlood Cellsbusiness.industryMacrophageslcsh:RAnti angiogenicBiology and Life SciencesMagnetic resonance imagingCell BiologyAtherosclerosisFumagillin - Therapeutic use.Atherosclerosis - Chemotherapy.Disease Models AnimalFumagilina - Uso terapéutico.LiposomesCardiovascular AnatomyNanoparticlesBlood Vesselslcsh:QbusinessPloS one
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CommercialOriganum compactumBenth. andCinnamomum zeylanicumBlume essential oils against natural mycoflora in Valencia rice

2015

Chemical composition of commercial Origanum compactum and Cinnamomum zeylanicum essential oils and the antifungal activity against pathogenic fungi isolated from Mediterranean rice grains have been investigated. Sixty-one compounds accounting for more than 99.5% of the total essential oil were identified by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Carvacrol (43.26%), thymol (21.64%) and their biogenetic precursors p-cymene (13.95%) and γ-terpinene (11.28%) were the main compounds in oregano essential oil, while the phenylpropanoids, eugenol (62.75%), eugenol acetate (16.36%) and (E)-cinnamyl acetate (6.65%) were found in cinnamon essential oil. Both es…

FusariumAntifungal AgentsCinnamomum zeylanicumCyclohexane MonoterpenesMicrobial Sensitivity TestsPlant ScienceBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundAscomycotaFusariumlawOriganumEugenolBotanyOils VolatilePlant OilsCarvacrolFood scienceThymolEssential oilMyceliumbiologyOrganic ChemistryAlternariafood and beveragesOryzabiology.organism_classificationCinnamomum zeylanicumEugenolchemistryCinnamatesMonoterpenesCymenesGas chromatographyNatural Product Research
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