Search results for "Tertiary"

Appropriateness of surgery performed for abdominal aortic aneurysm at tertiary hospitals in Spain

2021

Background: The aim of this study was to analyze the appropriateness of the type of repair (open or endovascular) performed for abdominal aortic aneurysm (AAA) in five university hospitals in Spain, according to evidence-based recommendations. Methods: A multicenter, retrospective cross-sectional study of patients with AAA who underwent elective open surgical repair (OSR) or endovascular aneurysm repair (EVAR). Data were collected on demographic and clinical variables and type of surgical repair. A pair of vascular surgeons from each participating hospital performed a blinded assessment based on GRADE recommendations. The concordance between the two evaluators and the agreement between thei…

[60]Fullerene l -Amino Acids and Peptides: Synthesis under Phase-Transfer Catalysis Using a Phosphine–Borane Linker. Electrochemical Behavior

2017

International audience; A new method to link amino acid and peptide derivatives to [60]fullerene is described. It uses hydrophosphination with a secondary phosphine borane. First, the stereoselective synthesis of secondary phosphine borane amino acid derivatives was achieved by alkylation of phenylphosphine borane with gamma-iodo-alpha-amino ester reagents under phase transfer catalysis (PTC). Second, a sec-phosphine borane amino ester was saponified and coupled with alpha,gamma-diamino esters to afford the corresponding dipeptide derivatives in good yields. Finally, the hydrophosphination reaction of [60]fullerene by the sec-phosphine borane compounds was performed under PTC to obtain C-60…

Tertiary teachers with dyslexia as narrators of their professional life and identity

2015

Kres ludzkiego tchnienia... kres ludzkiej godności, czyli o więziennej degradacji skazanych poszkodowanych

2017

THE EVOLUTION OF THE SEWAGE TREATMENT PROCESS IN ROMANIA IN THE LAST 30 YEARS: CASE STUDY RÂMNICU VÂLCEA

2012

The evolution of the sewage treatment process in Romania in the last 30 years: case study Râmnicu Vâlcea. Most studies made at national level in the domain of hydrology target the surface water topic, analyzing the hydrometric and hydrologic characteristics and the quality of the water for certain catchment areas. This paper aims instead the relatively new field of urban hydrology, more exactly the urban wastewater treatment process. The study is based on the observations made in the first half of the year 2010 at the wastewater treatment plant from Râmnicu Vâlcea and on the analysis of some relevant wastewater quality indicators before and after the treatment process for the period between…

Nuevas faunas de micromamíferos del Terciario continental de la Depresión Intermedia (provincia de Cuenca, España centro-oriental)

1986

In this paper the fossil content of nine new micromammal bearing localities and that of 15 levels in a borehole from the Loranca Basin (eastern Tague Basin, Prov. of Cuenca) is described. The age ranges from early Arvernian (Late Oligocene) to Turolian (Late Miocene). 47 rodent and lagomorph taxons have been found which are arranged in 8 biostratigraphic units. The Loranca-2 borehole contains 15 fossiliferous levels covering the Upper Oligocene/Lower Miocene. These additional data complete the faunal sequence published by Díaz & López(1919). The stratigraphic framework of the basin needs a revision because of the new faunal data.<br><br>Se presenta una serie de 9 nuevos yaci…

Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

2019

σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…

Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120.

2015

International audience; Modified nucleotide 5-methylcytosine (m(5)C) is frequently present in various eukaryotic RNAs, including tRNAs, rRNAs and in other non-coding RNAs, as well as in mRNAs. RNA: m(5)C-methyltranferases (MTases) Nop2 from S. cerevisiae and human proliferation-associated nucleolar antigen p120 are both members of a protein family called Nop2/NSUN/NOL1. Protein p120 is well-known as a tumor marker which is over-expressed in various cancer tissues. Using a combination of RNA bisulfite sequencing and HPLC-MS/MS analysis, we demonstrated here that p120 displays an RNA:m(5)C-MTase activity, which restores m(5)C formation at position 2870 in domain V of 25S rRNA in a nop2 Delta …

Challenges and Opportunities of English Grammar Acquisition by Distance at the Tertiary Level

2021

Distance learning introduced in almost all educational establishments in spring 2020 has raised interest among researchers how to deal with it in a more productive way. Thus, the goal of the research was to find out undergraduates’ views on distance learning of English grammar and the use of online revision materials in developing students’ independent study skills at a tertiary institution in Latvia. the research tool was a questionnaire consisting of open-ended and closed questions. Twenty-three students answered the survey questions. the research results indicate that studying by distance is preferred because it allows the students to choose the study time and place, to develop their tim…

Vienaudžu atgriezeniskās saites izmantošana lietišķās sarakstes mācīšanā augstskolā

2018

Tā kā rakstu valodas pilnveide ir aktuāla tēma augstskolā, bija svarīgi uzzināt par vienaudžu atgriezeniskās saites īstenošanas efektivitāti darījumu vēstuļu apguvē. Uzmanība tika pievērsta lietišķai sarakstei angļu valodā, jo šim žanram ir svarīga loma cilvēku profesionālajā un ikdienas dzīvē. Lai sasniegtu izvirzīto mērķi, gadījuma izpēte tika izmantota kā galvenā pētniecības metode. Pētniecības dati tika iegūti ar pirms- un pēcaptaujām, pirms- un pēctestiem, ieskaitot kvalitatīvo un kvantitatīvo paraugu analīzes. Pētījumā piedalījās divdesmit četri pilna laika trešā semestra bakalaura studiju programmas studenti, kuri mācās angļu filoloģiju kādā universitātē Latvijā. Pētījuma rezultāti a…