Search results for "Testing"
showing 10 items of 1769 documents
The harp: a vehicle crash test apparatus for full-scale crash test experiments
2012
Published version of an article in the journal: The International Journal of Advanced Manufacturing Technology. Also available from the publisher at: http://dx.doi.org/10.1007/s00170-012-3960-3 The current paper describes an apparatus for full-scale vehicle crash test experimentation. This apparatus is referred to as the harp. In brief, the harp may either accelerate a trolley which is impacted into a test vehicle or the test vehicle itself may be accelerated and impacted into an object such as a barrier, a pole, or another vehicle. If a trolley is accelerated, it is equipped with load cells to record the axial crushing force. If a test vehicle is accelerated, it is equipped with a three-ax…
Sorption Equilibria of Ethanol on Cork
2013
International audience; We report here for the first time a thermodynamic study of gaseous ethanol sorption on raw cork powder and plate. Our study aims at a better understanding of the reactivity of this material when used as a stopper under enological conditions, thus in close contact with a hydroethanolic solution, wine. Sorption−desorption isotherms were accurately measured by thermogravimetry at 298 K in a large range of relative pressures. Sorption enthalpies were determined by calorimetry as a function of loading. Sorption−desorption isotherms exhibit a hysteresis loop probably due to the swelling of the material and the absorption of ethanol. Surprisingly, the sorption enthalpy of e…
Influence of Welding Time on Tensile-Shear Strength of Linear Friction Welded Birch (Betula pendula L.) Wood
2015
Linear friction welding of wood is a bonding process applied to wood and during which a stiff bond line is formed by the softening and rehardening of wood components to form a composite material composed mainly of wood fibres embedded in a modified lignin matrix. Unfortunately, the bonds tend to spontaneously delaminate or lose their strength when exposed to moist conditions. Some approaches were previously applied to overcome this problem, but so far a suitable solution has not been found. This paper presents results of applying post-welding thermal modification to reduce the moisture sensitivity of welded wood. The experiments included welding of birch wood, thermal modification under sup…
Performance assessment of individual and ensemble data-mining techniques for gully erosion modeling
2017
Gully erosion is identified as an important sediment source in a range of environments and plays a conclusive role in redistribution of eroded soils on a slope. Hence, addressing spatial occurrence pattern of this phenomenon is very important. Different ensemble models and their single counterparts, mostly data mining methods, have been used for gully erosion susceptibility mapping; however, their calibration and validation procedures need to be thoroughly addressed. The current study presents a series of individual and ensemble data mining methods including artificial neural network (ANN), support vector machine (SVM), maximum entropy (ME), ANN-SVM, ANN-ME, and SVM-ME to map gully erosion …
Palliative Treatment of Dyspnea With Epidural Methadone in Advanced Emphysema
2005
This study investigated whether epidural methadone perfusion at the thoracic level can mitigate dyspnea in patients with advanced emphysema.Open-label clinical trial without a control group.University hospital.The inclusion criteria were a diagnosis of emphysema, basal dyspnea index (Mahler scale)or = 3, FEV(1)or = 35%, and no indication for pneumoreduction or lung transplantation surgery.An epidural catheter was inserted at the thoracic level connected to a perfusion pump for administering methadone (6 mg/24 h). Assessments were made at baseline, 1 week, and 1 month after catheter insertion.Pulmonary function tests were performed, and determinations were made of arterial blood gas levels, …
Value of genetic and epigenetic testing as biomarkers of response to antidepressant treatment
2013
Major depressive disorder (MDD) is one of the most prevalent and disabling psychiatric disorders worldwide and therefore an important public health priority. The selection process of antidepressant treatment is primarily guided by trial and error, and the outcomes with current antidepressant strategies are disappointing. The biological background of the disease is heterogeneous with presumably multiple biological systems involved. With the aim to individualize antidepressant treatment, multiple candidate gene and a few genome-wide association studies have been performed, but so far with very limited success. To address the dynamic changes of depressive symptoms and their response to treatme…
Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation
1995
Rat liver parenchymal cells (PC) were isolated by EDTA perfusion and were purified by a subsequent Percoll centrifugation. The isolated PC had a viability of 95%, as judged by trypan blue exclusion. Freshly isolated PC were cryopreserved with an optimized protocol in a computer-controlled freezer. After thawing, the PC still retained a viability of 89%. The activities of representative xenobiotic metabolizing enzymes were compared between freshly isolated and cryopreserved PC after thawing. The cytochrome P450 content and the cytochrome P450 2C11 isoenzyme activity, determined by hydroxylation of testosterone in intact cells, were not affected by the cryopreservation. The following phase II…
Graphene coating obtained in a cold-wall CVD process on the Co-Cr Alloy (L-605) for medical applications
2021
Graphene coating on the cobalt-chromium alloy was optimized and successfully carried out by a cold-wall chemical vapor deposition (CW-CVD) method. A uniform layer of graphene for a large area of the Co-Cr alloy (discs of 10 mm diameter) was confirmed by Raman mapping coated area and analyzing specific G and 2D bands
Recomendaciones para la determinación de HER2 en cáncer de mama. Consenso Nacional de la Sociedad Española de Anatomía Patológica ( SEAP ) y de la So…
2009
La identificación de los carcinomas de mama con amplificación/sobreexpresión de HER2 es crítica en la práctica clínica diaria ya que estas neoplasias requieren un tratamiento específico que incluye el uso de terapias dirigidas. Tanto las técnicas de hibridación in situ como las técnicas inmunohistoquímicas son métodos apropiados para la identificación de cánceres de mama HER2 positivos. Sin embargo, numerosos estudios, incluidos los desarrollados por la Asociación para la Garantía de Calidad en Patología de la SEAP (AGCP) y la experiencia de centros de referencia nacionales en la determinación de HER2 han puesto de manifiesto importantes problemas de reproducibilidad entre laboratorios. Por…
Rhinomanometry: point of care test (POCT) for allergic rhinitis in children?
2021
Allergic rhinitis (AR) is a global health problem: its prevalence is 23% in Europe, although it is underestimated because as many as 45% of the cases remain undiagnosed. Globally, almost 500 million people suffer from AR, which shows its increasing incidences. The diagnostic course of AR is based on clinical history, supported by anterior rhinoscopy. This inspects the anterior part of the nasal cavity accompanied by allergic sensitivity tests (cutaneous allergic skin tests or specific immunoglobulin E levels). The availability of standardised diagnostic procedures is able to provide objective evaluations of inflammatory situation, and the degree of nasal obstruction may give an advantage in…