Search results for "Therapy planning"

showing 4 items of 54 documents

Dose calculation in biological samples in a mixed neutron-gamma field at the TRIGA reactor of the University of Mainz

2010

To establish Boron Neutron Capture Therapy (BNCT) for non-resectable liver metastases and for in vitro experiments at the TRIGA Mark II reactor at the University of Mainz, Germany, it is necessary to have a reliable dose monitoring system. The in vitro experiments are used to determine the relative biological effectiveness (RBE) of liver and cancer cells in our mixed neutron and gamma fi eld. We work with alanine detectors in combination with Monte Carlo simulations, where we can measure and characterize the dose. To verify our calculations we perform neutron fl ux measurements using gold foil activation and pin-diodes . Material and methods . When L- α -alanine is irradiated with ionizing …

inorganic chemicalsPhysics::Instrumentation and DetectorsQuantitative Biology::Tissues and OrgansPhysics::Medical PhysicsBoron Neutron Capture TherapyValidation Studies as TopicModels BiologicalIonizing radiationTRIGAHospitals UniversityNuclear ReactorsCell Line TumorGermanyRelative biological effectivenessMedicineDosimetryHumansRadiology Nuclear Medicine and imagingNeutronNeutronsbusiness.industryRadiotherapy Planning Computer-AssistedRadiochemistryLiver NeoplasmsRadiotherapy DosageHematologyGeneral MedicineHep G2 CellsNeutron temperatureNeutron captureOncologyGamma RaysAbsorbed dosebusinessNuclear medicineColorectal Neoplasms
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Impact of the Tiloop Bra mesh in CT images and dose delivery in breast radiotherapy

2012

A new titanized breast mesh, TiLOOP Bra, is currently available for implantation in patients who require radiotherapy. The purpose of this work is to study the dosimetric effect of the presence of a TiLOOP Bra mesh on breast radiation treatment and radiographic imaging. The dosimetric effects have been measured for three X‐ray energies: 1.25 MeV, 6 MV and 18 MV, using radiochromic films placed at three different depths. These depths are representative of mesh location in breast during the radiotherapy treatment and hence, are of interest in this study. In order to assess the disturbance in a radiographic image, different computed tomographic (CT) studies of the mesh have been performed. The…

medicine.medical_specialtyBreast Implantsmedicine.medical_treatmentRadiographyBreast Neoplasmsmetallic artifactprothesesHounsfield scalemedicineRadiation Oncology PhysicsHumansDosimetryRadiology Nuclear Medicine and imagingInstrumentationtitanizationDose deliveryRadiationPhantoms Imagingbusiness.industryRadiotherapy Planning Computer-AssistedRadiotherapy DosageSurgical MeshRadiation therapySurgical meshmeshAbsorbed doseRadiographic Image Interpretation Computer-AssistedFemaleRadiologyTomographyTomography X-Ray ComputedbusinessNuclear medicine
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Exclusive MRI-based tandem and colpostats reconstruction in gynaecological brachytherapy treatment planning

2008

Purpose: According to the GYN GEC-ESTRO Recommendations, MRI is needed with the modality of T2 weighted. CT-MR compatible tandem Plus colpostats (T/C) (Nucletron) is widely used in cervical brachytherapy. The major challenge of MRI is the lack of dummy catheters. Therefore, an additional imaging modality is usually required. One disadvantage of sliced-based reconstruction is that resolution in longitudinal directions can be affected by the slice thickness. The aim of this study is to present a modified T/C applicator in which the catheter visibility is significantly improved. Methods and materials: A modification to the existing T/C applicator has been made available, increasing the cathete…

medicine.medical_specialtyGenital Neoplasms Femalebusiness.industryRadiotherapy Planning Computer-AssistedSlice thicknessmedicine.medical_treatmentBrachytherapyBrachytherapyRadiotherapy DosageHematologyMagnetic Resonance ImagingCatheterizationCatheterOncologymedicineHumansDosimetryFemaleRadiology Nuclear Medicine and imagingRadiologyNuclear medicinebusinessRadiation treatment planningT2 weighted
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Verification of a commercial implementation of the Macro-Monte-Carlo electron dose calculation algorithm using the virtual accelerator approach.

2009

Abstract In this work, the accuracy of the implementation of the Macro Monte Carlo electron dose calculation algorithm into the radiation therapy treatment planning system Eclipse is evaluated. This implementation – called eMC – uses a particle source based on the Rotterdam Initial Phase-Space model. A three-dimensional comparison of eMC calculated dose to dose distributions resulting from full treatment head simulations with the Monte Carlo code package EGSnrc is performed using the ‘virtual accelerator’ approach. Calculated dose distributions are compared for a homogeneous tissue equivalent phantom and a water phantom with air and bone inhomogeneities. The performance of the eMC algorithm…

medicine.medical_specialtyMonte Carlo methodBiophysicsElectronsImaging phantomUser-Computer InterfaceElectron dosemedicineHumansRadiology Nuclear Medicine and imagingMedical physicsMacroLungEclipsePhysicsRadiological and Ultrasound TechnologyPhantoms ImagingRadiotherapy Planning Computer-AssistedCalculation algorithmWaterRadiotherapy DosageSpineComputational physicsRadiographyTracheaTissue equivalentHomogeneousHeadMonte Carlo MethodAlgorithmsZeitschrift fur medizinische Physik
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