Search results for "Thermal"

showing 10 items of 3576 documents

Arynic species; effect of substituents on the reactivity of monosubstituted dehydrobenzenes

1986

Abstract Evidence is presented demonstrating the existence of free dehydrobenzenes in the thermal decomposition of diaryliodonium-2-carboxylates, and that o-benzyne itself and its 4-methyl-, 4-chloro-,4-bromo- and 4-nitro-derivatives are generated from insoluble polymer-bound precursors and trapped by a second solid phase in Diels-Alder reactions. Lifetimes for these elusive species are determined.

Bicyclic moleculeChemistryOrganic ChemistryThermal decompositionBiochemistryArynechemistry.chemical_compoundComputational chemistryPhase (matter)Drug DiscoveryOrganic chemistryReactivity (chemistry)PhenolsPyrolysisDiels–Alder reactionTetrahedron
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Solid state structural studies of five bile acid derivatives

2008

Five synthetically important bile acid derivatives have been characterized by 13 C CP-MAS, X-ray diffraction (both single crystal and powder), FTIR, and thermoanalytical (DSC and TG) methods. The crystallinity of all these derivatives is high, which can be deducted from the 13 C CP-MAS and powder X-ray diffraction data. Two of the compounds showed polymorphism, and one polymorph was structurally elucidated for both by comparing single crystal and powder X-ray diffraction data.

Bile acidmedicine.drug_classChemistryOrganic ChemistryNuclear magnetic resonance crystallographyAnalytical ChemistryInorganic ChemistryCrystallinityCrystallographyPolymorphism (materials science)X-ray crystallographymedicineFourier transform infrared spectroscopyThermal analysisSingle crystalSpectroscopyJournal of Molecular Structure
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Photoluminescent and Slow Magnetic Relaxation Studies on Lanthanide(III)-2,5-pyrazinedicarboxylate Frameworks

2017

In the series described in this work, the hydrothermal synthesis led to oxidation of the 5-methyl-pyrazinecarboxylate anion to the 2,5-pyrazinedicarboxylate dianion (2,5-pzdc) allowing the preparation of three-dimensional (3D) lanthanide(III) organic frameworks of formula {[Ln2(2,5-pzdc)3(H2O)4]·6H2O}n [Ln = Ce (1), Pr (2), Nd (3), and Eu (4)] and {[Er2(2,5-pzdc)3(H2O)4]·5H2O}n (5). Single-crystal X-ray diffraction on 1–5 reveals that they crystallize in the triclinic system, P1 space group with the series 1–4 being isostructural. The crystal structure of the five compounds are 3D with the lanthanide(III) ions linked through 2,5-pzdc2– dianions acting as two- and fourfold connectors, buildi…

BinodalLanthanidePhotoluminescence010405 organic chemistryChemistryInorganic chemistryCrystal structureTriclinic crystal system010402 general chemistry01 natural sciences0104 chemical sciencesInorganic ChemistryCrystallographyHydrothermal synthesisPhysical and Theoretical ChemistryIsostructuralLuminescenceInorganic Chemistry
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Aqueous phase/nanoparticles interface: hydroxypropyl cellulose adsorption and desorption triggered by temperature and inorganic salts

2012

The study highlighted the main forces driving the adsorption of hydroxypropyl cellulose (HPC) onto clay nanoparticles with a disk-like shape (Laponite RD). Modeling the isothermal titration calorimetry data provided the key thermodynamic properties, which enabled us to discuss the microscopic aspects contributing to the energetic and the entropic changes of the polymer adsorption at the nanoparticle/liquid interface. We evidenced that the process is strongly enthalpy-driven and that the interactions lead to constraints of the HPC configuration at interface. The functionalized nanoparticles enhanced the polymer solubility in water expanding the one-phase area of the binodal curve. Temperatur…

BinodalMaterials scienceHydroxypropyl cellulosenanoparticles interface cellulose calorimetryNanoparticleIsothermal titration calorimetryGeneral ChemistryPolymer adsorptionCondensed Matter Physicschemistry.chemical_compoundAdsorptionchemistryChemical engineeringDesorptionOrganic chemistrySolubilitySettore CHIM/02 - Chimica Fisica
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Spectroscopic study of the loading of cationic porphyrins by carbon nanohorns as high capacity carriers of photoactive molecules to cells

2019

Carbon nanomaterials are attractive candidates for drug delivery due to their high surface area, ease of functionalisation and biocompatibility. This work describes the spectroscopic monitoring of the loading capacity of oxidised carbon nanohorns for two cationic porphyrins. Addition of the COOH functionalised carbon nanohorns to both meso-tetra(4-N-methylpyridyl) free base (H2TMPyP4) and platinum (PtTMPyP4) porphyrin in aqueous solution results in hypochromism of the Soret band and quenching of the porphyrin emission. These changes are used to monitor the non-covalent binding interactions with the nanohorn surface and determine the surface loading. The colloidal stability of the nanohorns …

BiocompatibilityNANOTUBESBiomedical Engineeringchemistry.chemical_element02 engineering and technology010402 general chemistryPhotochemistry01 natural scienceschemistry.chemical_compoundpolycyclic compoundsGeneral Materials ScienceDRUG-DELIVERYPHOTOTHERMAL THERAPYNANOMATERIALSQuenching (fluorescence)Aqueous solutionCationic polymerizationFree baseSettore CHIM/06 - Chimica OrganicaGeneral ChemistryGeneral Medicine021001 nanoscience & nanotechnologyPorphyrin0104 chemical scienceschemistry0210 nano-technologyPlatinumCarbonJournal of Materials Chemistry B
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Effect of actively targeted copolymer coating on solid tumors eradication by gold nanorods-induced hyperthermia.

2020

Efforts in the field of anticancer therapy are increasingly focusing on the development of localized and selective treatments. Photothermal therapy (PTT) can lead to a spatially confined death of cancer cells, exploiting an increasing in temperature generated after UV-NIR irradiation of peculiar materials. Herein, a new actively targeted gold-based drug delivery system, named PHEA-LA-Fol-AuNRs/Iri, was explored for hyperthermia and chemotherapy colon cancer treatment. Gold nanorods were stabilized using a folate-derivative of α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA-LA-PEG-FA) as coating agent and then loaded with the antineoplastic drug irinotecan (Iri). The efficacy of empty and i…

BiodistributionColorectal cancerPolymersPharmaceutical Science02 engineering and technology030226 pharmacology & pharmacy03 medical and health sciencesMice0302 clinical medicineIn vivoCell Line TumorNeoplasmsmedicineGold nanorodsHyperthermiaPhotothermal therapySolid tumorMagnetic resonance imaging folic acidAnimalsHyperthermiaTissue DistributionNanotubesChemistryCancerHyperthermia InducedPhotothermal therapyPhototherapy021001 nanoscience & nanotechnologymedicine.diseaseIrinotecanDrug deliveryCancer cellCancer researchGold0210 nano-technologymedicine.drugInternational journal of pharmaceutics
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Iron isotope signature of magnetofossils and oceanic biogeochemical changes through the Middle Eocene Climatic Optimum.

2021

21 pages; International audience; Magnetotactic bacteria (MTB) intracellularly precipitate magnetite (Fe3O4) crystals that can be preserved in the geological record. When MTB die, the so-called magnetofossils constitute valuable proxies for paleoenvironmental reconstructions and are suspected to represent some of the oldest traces of biomineralization on Earth. Yet, the biogenicity of putative magnetofossils found in ancient terrestrial and extra-terrestrial samples is still largely debated and their significance for past climate still holds uncertainties. Here we studied a sedimentary sequence from the Indian Ocean (ODP Hole 711A) recording the Middle Eocene Climatic Optimum (MECO) through…

Biogeochemical cycle010504 meteorology & atmospheric sciencesGeochemistryTrace elementIron isotopesFe sequential extraction010502 geochemistry & geophysicsMass-independent fractionationHyperthermal01 natural sciencesDiagenesischemistry.chemical_compoundMagnetotactic bacteriaIsotope fractionationMagnetofossilschemistry13. Climate actionGeochemistry and Petrology[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/GeochemistryBiosignatureMECOMagnetofossilGeology0105 earth and related environmental sciencesMagnetite
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Influence of chitin nanocrystals on the dielectric behaviour and conductivity of chitosan-based bionanocomposites

2018

[EN] A series of bionanocomposite films based on chitosan, reinforced with chitin nanocrystals, were developed, and assessed in terms of dielectric behaviour and conductivity by using an experimental methodology that allows avoiding the conductivity contribution and the exclusion of contact and interfacial polarization effects. The dielectric relaxations at low and high frequency and temperatures were modeled by Havriliak-Negami functions. Below the glass transition temperature (Tg), the gamma and beta relaxations were observed, which were related to intramolecular and non-cooperative segmental movements. At higher temperatures, an intermolecular and cooperative macromolecular movement, rel…

BionanocompositesSolucions polimèriquesMaterials scienceMaterial testingIonic bonding02 engineering and technologyDielectricActivation energyConductivity010402 general chemistry01 natural sciencesChitosanchemistry.chemical_compoundElectrical resistivity and conductivity[CHIM.ANAL]Chemical Sciences/Analytical chemistryComposite materialsChitosanChitosanIntermolecular forceGeneral EngineeringINGENIERIA DE LOS PROCESOS DE FABRICACION[CHIM.MATE]Chemical Sciences/Material chemistryCiència dels materials021001 nanoscience & nanotechnology0104 chemical sciencesChitin nanocrystals[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry[CHIM.POLY]Chemical Sciences/PolymersChemical engineeringchemistryMAQUINAS Y MOTORES TERMICOSCeramics and CompositesChitin nanocrystal0210 nano-technologyGlass transitionDielectric thermal analysis (DETA)
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Trehalose effects on α-crystallin aggregates

2007

alpha-Crystallin in its native state is a large, heterogeneous, low-molecular weight (LMW) aggregate that under certain conditions may progressively became part of insoluble high-molecular weight (HMW) systems. These systems are supposed to play a relevant role in eye lens opacification and vision impairment. In this paper, we report the effects of trehalose on alpha-crystallin aggregates. The role of trehalose in alpha-crystallin stress tolerance, chaperone activity and thermal stability is studied. The results show that trehalose stabilizes the alpha-crystallin native structure, inhibits alpha-crystallin aggregation, and disaggregates preformed LMW systems not affecting its chaperone acti…

BiophysicsMicroscopy Atomic ForceBiochemistrythermal stabilitychemistry.chemical_compoundCrystallinNative stateThermal stabilityBenzothiazolesalpha-Crystallinsalpha-crystallinChaperone activityProtein Structure QuaternaryEye lensMolecular BiologyNative structureCircular DichroismTrehalosefood and beveragesCell BiologyTrehaloseeye diseaseschaperone activityThiazolesSpectrometry FluorescencechemistryBiochemistryaggregatesα-Crystallin Trehalose Aggregates Chaperone activity Thermal stabilitysense organsBiochemical and Biophysical Research Communications
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Effects of halloysite content on the thermo-mechanical performances of composite bioplastics

2020

Abstract The aim of this study is the design and preparation of Mater-Bi/halloysite nanocomposite materials that could be employed as bioplastics alternative to the petroleum derived products. The biocomposite materials at variable halloysite content (from 0 to 30 wt%) were prepared by using the solvent casting method. We investigated the mechanical behaviour and the thermal properties of the prepared nanocomposites in order to estimate their suitability as biocompatible packaging materials. The thermo-mechanical characteristics were correlated to the nanocomposites' morphologies, which were studied by Scanning Electron Microscopy (SEM). As a general result, the physico-chemical performance…

BiopolymerMaterials scienceComposite number020101 civil engineering02 engineering and technologyDMAengineering.materialHalloysite0201 civil engineeringGeochemistry and PetrologyUltimate tensile strengthThermal stabilityComposite materialchemistry.chemical_classificationTGANanocompositeNanocompositeHalloysiteGeologyPolymer021001 nanoscience & nanotechnologyCastingBioplasticchemistryengineeringBiocomposite0210 nano-technologyApplied Clay Science
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