Search results for "Thiazine"

showing 10 items of 67 documents

CCDC 1534633: Experimental Crystal Structure Determination

2017

Related Article: Arno Schneeweis, Andreas Neidlinger, Guido J. Reiss, Walter Frank, Katja Heinze, Thomas J. J. Müller|2017|Org.Chem.Front.|4|839|doi:10.1039/C7QO00188F

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters4-(4-t-butylphenyl)-4H-bisthieno[23-b:3'2'-e][14]thiazineExperimental 3D Coordinates
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CCDC 1839885: Experimental Crystal Structure Determination

2018

Related Article: Cristina Mulet, Marcos Escolano, Sebastián Llopis, Sergio Sanz, Carmen Ramírez de Arellano, María Sánchez‐Roselló, Santos Fustero, Carlos del Pozo|2018|Adv.Synth.Catal.|360|2885|doi:10.1002/adsc.201800548

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters4-acetyloctahydro-1H-1-pyrido[12-b][12]thiazine-11-dioneExperimental 3D Coordinates
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CCDC 1401764: Experimental Crystal Structure Determination

2015

Related Article: Lode De Munck, Alicia Monleón, Carlos Vila, M. Carmen Muñoz, José R. Pedro|2015|Org.Biomol.Chem.|13|7393|doi:10.1039/C5OB01012H

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters6-Bromo-4-((35-dimethoxyphenyl)ethynyl)-34-dihydro-123-benzoxathiazine 22-dioxideExperimental 3D Coordinates
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CCDC 1995029: Experimental Crystal Structure Determination

2020

Related Article: Justin J. Dressler, Joshua E. Barker, Lucas J. Karas, Hannah E. Hashimoto, Ryohei Kishi, Lev N. Zakharov, Samantha N. MacMillan, Carlos J. Gomez-Garcia, Masayoshi Nakano, Judy I. Wu, Michael M. Haley|2020|J.Org.Chem.|85|10846|doi:10.1021/acs.joc.0c01387

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters918-bis(4-t-butyl-26-dimethylphenyl)-514-[12]benzothiazino[4''3'':2'3']indeno[5'6':56]indeno[12-c][12]benzothiazine-551414-tetrone chloroform solvateExperimental 3D Coordinates
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CCDC 275791: Experimental Crystal Structure Determination

2006

Related Article: S.Jacquot-Rousseau, G.Schmitt, A.Khatyr, M.Knorr, M.M.Kubicki, E.Vigier, O.Blacque|2006|Eur.J.Org.Chem.|2006|1555|doi:10.1002/ejoc.200500538

Space GroupCrystallographyCrystal SystemCrystal StructureEthyl 2-((ethoxycarbonyl)methylthio)-55-diphenyl-56-dihydro-4H-14-thiazine-6-carboxylateCell ParametersExperimental 3D Coordinates
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CCDC 1494769: Experimental Crystal Structure Determination

2016

Related Article: Yulian Zagranyarski, Artem Skabeev, Yingjie Ma, Klaus Müllen, Chen Li|2016|Org.Chem.Front.|3|1520|doi:10.1039/C6QO00371K

Space GroupCrystallographyCrystal Systembenzo[45]quinolino[321-kl]phenothiazineCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2209228: Experimental Crystal Structure Determination

2022

Related Article: Miguel Gavara-Edo, Francisco Javier Valverde-Muñoz, Rosa Córdoba, M. Carmen Muñoz, Javier Herrero-Martín, José Antonio Real, Eugenio Coronado|2022|J.Mater.Chem.C|11|8107|doi:10.1039/D2TC04120K

Space GroupCrystallographybis(dihydrogen bis(pyrazolyl)borate)-(55'66'-tetrahydro-4H4'H-22'-bi-13-thiazine)-ironCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2209230: Experimental Crystal Structure Determination

2022

Related Article: Miguel Gavara-Edo, Francisco Javier Valverde-Muñoz, Rosa Córdoba, M. Carmen Muñoz, Javier Herrero-Martín, José Antonio Real, Eugenio Coronado|2022|J.Mater.Chem.C|11|8107|doi:10.1039/D2TC04120K

Space GroupCrystallographybis(dihydrogen bis(pyrazolyl)borate)-(55'66'-tetrahydro-4H4'H-22'-bi-13-thiazine)-ironCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Increased acidophilia of eosinophil granules after EDTA treatment

1986

The acidophilic reaction of eosinophil leucocyte granules from human, pig and horse blood smears was investigated by using May-Grünwald-Giemsa staining after previous treatment with EDTA and sodium citrate solutions. The same peak at 530 nm, but absorption values considerably higher than those of controls, were found in eosinophil granules after application of chelating agents, indicating that removal of metal cations could unmask basic groups in these structures.

SwineEdta treatmentBiologyCytoplasmic GranulesAzure Stainschemistry.chemical_compoundPhenothiazinesHorse bloodSodium citratemedicineAnimalsHumansChelationHorsesEdetic AcidGranule (cell biology)Cell BiologyHydrogen-Ion ConcentrationEosinophilStainingEosinophilsmedicine.anatomical_structureBiochemistrychemistryCytophotometryAnatomyEosinophil leucocyteThe Histochemical Journal
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Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives

2008

Abstract A series of easily affordable phenothiazine derivatives bearing a rigid but-2-ynyl amino side chain were synthesized and tested to evaluate the MDR reverting activity and full antitumor profile. Some compounds endowed with remarkable MDR reverting effect were identified, and the most active one ( 6c ) was shown to increase doxorubicin retention in multidrug resistant cells, suggesting a direct interaction with P-glycoprotein. Furthermore, a broad range of cellular activities were observed for different compounds. In particular, the ability of some derivatives to induce antiproliferative effects on resistant cell lines and to interfere with the G 1 phase of the cell cycle, a phase u…

Tertiary amineClinical BiochemistryPharmaceutical ScienceAntineoplastic AgentsApoptosisPharmacologyAntineoplastic agents phenothiazine derivatives drug resistance apoptosisBiochemistryStructure-Activity Relationshipchemistry.chemical_compoundPhenothiazinesCell Line TumorPhenothiazineDrug DiscoverymedicineHumansChemosensitizing agentDoxorubicinCytotoxicityMolecular BiologyMolecular StructureOrganic ChemistryCell cycleDrug Resistance MultipleMultiple drug resistancechemistryMechanism of actionDoxorubicinDrug Resistance NeoplasmSettore BIO/14 - FarmacologiaMolecular MedicineDrug Screening Assays Antitumormedicine.symptommedicine.drug
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