Search results for "Time point"
showing 10 items of 20 documents
Planning and Analysis of Trials Using a Stepped Wedge Design: Part 26 of a Series on Evaluation of Scientific Publications
2019
Background The stepped-wedge design (SWD) of clinical trials has become very popular in recent years, particularly in health services research. Typically, study participants are randomly allotted in clusters to the different treatment options. Methods The basic principles of the stepped wedge design and related statistical techniques are described here on the basis of pertinent publications retrieved by a selective search in PubMed and in the CIS statistical literature database. Results In a typical SWD trial, the intervention is begun at a time point that varies from cluster to cluster. Until this time point is reached, all participants in the cluster belong to the control arm of the trial…
I-states-as-objects-analysis (ISOA): Extensions of an approach to studying short-term developmental processes by analyzing typical patterns
2012
I-states-as-objects-analysis (ISOA) is a person-oriented methodology for studying short-term developmental stability and change in patterns of variable values. ISOA is based on longitudinal data with the same set of variables measured at all measurement occasions. A key concept is the i-state, defined as a person’s pattern of variable values at a specific time point. All i-states are first subjected to a classification analysis that results in a time-invariant classification characterized by a number of typical i-states. Each person is then characterized at each time point by the typical i-state he/she belongs to. Then the person’s sequences of typical i-states are analyzed with regard to …
Effects of ocean acidification on embryonic respiration and development of a temperate wrasse living along a natural CO2 gradient
2016
Volcanic CO2 seeps provide opportunities to investigate the effects of ocean acidification on organisms in the wild. To understand the influence of increasing CO2 concentrations on the metabolic rate (oxygen consumption) and the development of ocellated wrasse early life stages, we ran two field experiments, collecting embryos from nesting sites with different partial pressures of CO2 [pCO2; ambient (400 µatm) and high (800-1000 µatm)] and reciprocally transplanting embryos from ambient- to high-CO2 sites for 30 h. Ocellated wrasse offspring brooded in different CO2 conditions had similar responses, but after transplanting portions of nests to the high-CO2 site, embryos from parents that sp…
FLP estimation of semi-parametric models for space-time point processes and diagnostic tools
2015
Abstract The conditional intensity function of a space–time branching model is defined by the sum of two main components: the long-run term intensity and short-run term one. Their simultaneous estimation is a complex issue that usually requires the use of hard computational techniques. This paper deals with a new mixed estimation approach for a particular space–time branching model, the Epidemic Type Aftershock Sequence model. This approach uses a simultaneous estimation of the different model components, alternating a parametric step for estimating the induced component by Maximum Likelihood and a non-parametric estimation step, for the background intensity, by FLP (Forward Predictive Like…
Including covariates in a space-time point process with application to seismicity
2020
AbstractThe paper proposes a spatio-temporal process that improves the assessment of events in space and time, considering a contagion model (branching process) within a regression-like framework to take covariates into account. The proposed approach develops the forward likelihood for prediction method for estimating the ETAS model, including covariates in the model specification of the epidemic component. A simulation study is carried out for analysing the misspecification model effect under several scenarios. Also an application to the Italian seismic catalogue is reported, together with the reference to the developed R package.
Forward likelihood-based predictive approach for space-time point processes
2011
Dealing with data from a space–time point process, the estimation of the conditional intensity function is a crucial issue even if a complete definition of a parametric model is not available. In particular, in case of exploratory contexts or if we want to assess the adequacy of a specific parametric model, some kind of nonparametric estimation procedure could be useful. Often, for these purposes kernel estimators are used and the estimation of the intensity function depends on the estimation of bandwidth parameters. In some fields, like for instance the seismological one, predictive properties of the estimated intensity function are pursued. Since a direct ML approach cannot be used, we pr…
Windowed Etas Models With Application To The Chilean Seismic Catalogs
2015
Abstract The seismicity in Chile is estimated using an ETAS (Epidemic Type Aftershock sequences) space–time point process through a semi-parametric technique to account for the estimation of parametric and nonparametric components simultaneously. The two components account for triggered and background seismicity respectively, and are estimated by alternating a ML estimation for the parametric part and a forward predictive likelihood technique for the nonparametric one. Given the geographic and seismological characteristics of Chile, the sensitivity of the technique with respect to different geographical areas is examined in overlapping successive windows with varying latitude. A different b…
A space-time branching process with covariates
2018
The paper proposes a stochastic process that improves the assessment of seismic events in space and time, considering a contagion model (branching process) within a regression-like framework. The proposed approach develops the Forward Likelihood for prediction (FLP) method including covariates in the epidemic component.
Nonparametric intensity estimation in space-time point processes and application to seismological problems
2008
Space-Time Forecasting of Seismic Events in Chile
2017
The aim of this work is to study the seismicity in Chile using the ETAS (epidemic type aftershock sequences) space‐time approach. The proposed ETAS model is estimated using a semi‐parametric technique taking into account the parametric and nonparametric components corresponding to the triggered and background seismicity, respectively. The model is then used to predict the temporal and spatial intensity of events for some areas of Chile where recent large earthquakes (with magnitude greater than 8.0 M) occurred.