Search results for "Time point"

External validation of a prognostic model estimating the survival of patients with recurrent high-grade gliomas after reirradiation

2015

PURPOSE: We aimed to validate a controversial prognostic model for the survival of relapsed malignant glioma patients after reirradiation with an independent, multicentric patient cohort.METHODS AND MATERIALS: A total of 165 malignant glioma patients underwent reirradiation at 4 different institutions between 1994 and 2012. Twenty-two patients had a good (score 1), 44 had a moderate (score 2), and 99 had a poor prognosis (score 3 or 4). Four statistical methods were used to validate the prognostic model: First, we compared survival according to prognostic group in the construction and the validation cohort by visual comparison of the respective Kaplan-Meier plots. Second, discrimination was…

Nonparametric intensity estimation in space-time point processes and application to seismological problems

2008

Bodyweight, not age, determines oesophageal length and breaking strength in rats

2018

Delayed primary repair is still the method of choice in the management of long-gap oesophageal atresia in many centres, but the timing of anastomoses varies. Some assume the infant's bodyweight to be an important factor, whereas others prefer age. We therefore aimed to clarify whether age or bodyweight determined oesophageal length in a rodent model.We explanted the oesophagi of 20 Sprague-Dawley rats, aged 15 to 444 days (n = two per time point), measured bodyweight, oesophageal length, weight, and linear breaking strength to measure tissue resilience. Univariate and multivariate regression analyses were conducted to determine the influence of age and bodyweight on oesophageal length and l…

Financial contagion through space-time point processes

2020

AbstractWe propose to study the dynamics of financial contagion by means of a class of point process models employed in the modeling of seismic contagion. The proposal extends network models, recently introduced to model financial contagion, in a space-time point process perspective. The extension helps to improve the assessment of credit risk of an institution, taking into account contagion spillover effects.

I-states-as-objects-analysis (ISOA): Extensions of an approach to studying short-term developmental processes by analyzing typical patterns

2012

I-states-as-objects-analysis (ISOA) is a person-oriented methodology for studying short-term developmental stability and change in patterns of variable values. ISOA is based on longitudinal data with the same set of variables measured at all measurement occasions. A key concept is the i-state, defined as a person’s pattern of variable values at a specific time point. All i-states are first subjected to a classification analysis that results in a time-invariant classification characterized by a number of typical i-states. Each person is then characterized at each time point by the typical i-state he/she belongs to. Then the person’s sequences of typical i-states are analyzed with regard to …

Some extensions in space-time LGCP: application to earthquake data

2017

In this paper we aim at studying some extensions of complex space-time models, useful for the description of earthquake data. In particular we want to focus on the Log-Gaussian Cox Process (LGCP, [1]) model estimation approach, with some results on global informal diagnostics. Indeed, in our opinion the use of Cox processes that are natural models for point process phenomena that are environmentally driven could be a new approach for the description of seismic events. These models can be useful in estimating the intensity surface of a spatio-temporal point process, in constructing spatially continuous maps of earthquake risk from spatially discrete data, and in real-time seismic activity su…

Space-Time Forecasting of Seismic Events in Chile

2017

The aim of this work is to study the seismicity in Chile using the ETAS (epidemic type aftershock sequences) space‐time approach. The proposed ETAS model is estimated using a semi‐parametric technique taking into account the parametric and nonparametric components corresponding to the triggered and background seismicity, respectively. The model is then used to predict the temporal and spatial intensity of events for some areas of Chile where recent large earthquakes (with magnitude greater than 8.0 M) occurred.

Dual-Time Point [68Ga]Ga-PSMA-11 PET/CT Hybrid Imaging for Staging and Restaging of Prostate Cancer

2020

Routine [68Ga]Ga-PSMA-11 PET/CT (one hour post-injection) has been shown to accurately detect prostate cancer (PCa) lesions. The goal of this study is to evaluate the benefit of a dual-time point imaging modality for the staging and restaging of PCa patients. Biphasic [68Ga]Ga-PSMA-11 PET/CT of 233 patients, who underwent early and late scans (one/three hours post-injection), were retrospectively studied. Tumor uptake and biphasic lesion detection for 215 biochemically recurrent patients previously treated for localized PCa (prostatectomized patients (P-P)/irradiated patients (P-I) and 18 patients suspected of having primary PCa (P-T) were separately evaluated. Late [68Ga]Ga-PSMA-11 PET/CT …

Profiling children longitudinally: A three-year follow-up study of perceived and actual motor competence and physical fitness.

2020

Longitudinal designs enhance our understanding of children's development and its influence on movement behaviors and health. This three-year follow-up study aimed to develop profiles according to perceived and actual motor competence (MC) (locomotion, object control, and overall) and physical fitness in boys and girls longitudinally including children's temporal migrations among clusters in terms of profiling trends. A secondary aim was to compare physical activity participation and weight status at each time point according to these profiles. One hundred and four typically developing Spanish children (45.8% girls) between 4 and 9 years old at baseline participated in this study. Data were …

Effects of ocean acidification on embryonic respiration and development of a temperate wrasse living along a natural CO2 gradient

2016

Volcanic CO2 seeps provide opportunities to investigate the effects of ocean acidification on organisms in the wild. To understand the influence of increasing CO2 concentrations on the metabolic rate (oxygen consumption) and the development of ocellated wrasse early life stages, we ran two field experiments, collecting embryos from nesting sites with different partial pressures of CO2 [pCO2; ambient (400 µatm) and high (800-1000 µatm)] and reciprocally transplanting embryos from ambient- to high-CO2 sites for 30 h. Ocellated wrasse offspring brooded in different CO2 conditions had similar responses, but after transplanting portions of nests to the high-CO2 site, embryos from parents that sp…