Search results for "Timo"

Imaging to study solid tumour origin and progression: lessons from research and clinical oncology

2017

Biomedical imaging in recent decades has clarified our understanding of normal and pathological cellular processes in vivo. In particular, this approach recently provided insights into processes occurring at a molecular or genetic level rather than at the anatomical level. The evolution of this discipline by engineering have led to its integration into biomedical research to (1) increase sensitivity and resolution imaging and to (2) improve tissue and cell specificity. Currently, imaging approaches are used in three different biomedical areas: (a) identification of cellular processes in physiological and disease state; (b) in vivo single-cell imaging; and (c) identification of new prognosti…

Tumors of the central nervous system in children and adolescents.

2011

Multimodal treatment approaches for children with tumors of the central nervous system (CNS) have markedly contributed to improved survival. Before 1970, the survival rate among children with medulloblastoma, the most common malignant CNS tumor in children, was about 20%. At present, in contrast, cure can be achieved in more than 75% of children with a favorable constellation of risk factors. In this review article for clinicians, we give an overview of the current understanding of the pathology, presenting manifestations, early diagnosis, and treatment of CNS tumors in children and adolescents.We report the research findings of the German Treatment Network "HIT" and selectively review the …

Nomi di piante e nomi di santi. San Giovanni nella lessicografia botanica siciliana

2022

A Mario Alinei si deve l’idea che alcune porzioni del lessico della nostra lingua siano più conservative di altre e che esse manifestino traccia, nelle circostanze più fortunate, delle diverse stratificazioni iconimiche prodottesi secolarmente. Il contributo rintraccia, nella lessicografia dialettale siciliana, i tipi lessicali legati alla agiofitonimia, concentrandosi in particolare sulle erbe dedicate a san Giovanni. Si propongono percorsi motivazionali anche alla luce di ipotesi etimologiche inedite.

The contribution of geographical certification programs to farm income and rural economies: The case of Pecorino Siciliano PDO

2021

This study attempts to measure the capacity of the EU geographical certification scheme to positively influence the price of certified products and the incomes of their producers. A comparison of the economic results of two cheese-producing dairy farm enterprises with different business strategies and locations within the Sicilian hinterlands is performed in order to determine the transformation value of each dairy’s sheep milk into pecorino cheese (with and without the Protected Designation of Origin, or PDO, certification) and the related joint products (ricotta). The economic convenience of the total transformation of sheep milk into Pecorino Siciliano PDO and ricotta is also appraised. …

Analyzing American Public Diplomacy: The case of Brand USA. When Tourism becomes an Ideological Tool

2016

This paper aims to study the communicative strategies used in the American campaign of public diplomacy.Our objective in this work is twofold: first, to verify whether behind the action of rebranding the image of the U.S.A. there is an ideological agenda; second, to identify the communication dynamics - both textual and semiotic - which have contributed to make the campaign successful and whether they are in line with the communicative profile of the U.S.A., adopting a handful of current models in intercultural studies.

Alle origini delle consuetudini marittime mediterranee. Symbola, sylai e lex Rhodia

2013

Anna hyvät eväät : visuaalinen ja kielellinen analyysi elintarvikkeiden televisiomainoksista

2016

Elämme jatkuvasti medioituvassa maailmassa, jossa yksi televisiomainos voi tavoittaa jopa yli miljoona katsojaa. Mainosten tehtävänä on aina vaikuttaa katsojaan, ja tästä syystä ne ovatkin tärkeä tutkimuskohde. Mainokset eivät ainoastaan peilaa meidän maailmaamme, vaan myös rakentavat merkityksiä ja nostavat tietyt arvot esiin toisten kustannuksella. Näitä arvoja ja merkityksiä on syytä tarkastella kriittisesti jopa kaikkein tutuimmista arkemme teksteistä. Tutkielmassani syvennyn mainonnan keinoihin tutkiessani, millaisia arvoja ja asenteita Valio Oy:n ja Arla Oy:n mainoksissa nousee esiin, ja millaista todellisuuskuvaa niissä representoidaan. Tutkimukseni tarkoituksena onkin selvittää, mil…

Identification <i>In Silico</i> and <i>In Vitro</i> of Novel Trypanosomicidal Drug-like Compounds

2012

Atom-based bilinear indices and linear discriminant analysis are used to discover novel trypanosomicidal compounds. The obtained linear discriminant analysis-based quantitative structure–activity relationship models, using non-stochastic and stochastic indices, provide accuracies of 89.02% (85.11%) and 89.60% (88.30%) of the chemicals in the training (test) sets, respectively. Later, both models were applied to the virtual screening of 18 in-house synthesized compounds to find new pro-lead antitrypanosomal agents. The in vitro antitrypanosomal activity of this set against epimastigote forms of Trypanosoma cruzi is assayed. Predictions agree with experimental results to a great extent (16/18…

Optimal Usage of Multiple Network Connections

2008

In the future mobile networks, a mobile terminal is able to select the best suitable network for each data transmission. The selection of a network connection to be used has been under a lot of study. In this paper, we consider a more extensive case in which we do not select a network connection but use several network connections simultaneously to transfer data. When data is transferred using multiple network connections, a network connection has to be selected for each component of the data. We have modelled this problem as a multiobjective optimization problem and developed a heuristic to solve the problem fast in a static network environment. In this paper, we discuss solving the proble…

Determinants affecting consumers' attention to fish eco-labels in purchase decisions: a cross-country study

2022

PurposeThe purpose of this study was to investigate the role of consumer altruism and other socio-cultural factors in predicting how much attention consumers pay to seafood eco-labels.Design/methodology/approachThe empirical investigation was carried out by administering an online questionnaire to a sample of Italian and Spanish people from December 2019 to April 2020. After carrying out the principal component analysis procedure, the work made use of an ordinal logistic regression.FindingsBoth Italian and Spanish consumers with an altruistic attitude, who feel that food produced in a sustainable way can protect the environment and workers, appear more likely to take an eco-label into accou…