Search results for "Tipa"
showing 10 items of 596 documents
Food intolerance and chronic constipation: manometry and histology study
2006
BACKGROUND: Chronic constipation in children can be caused by cows' milk intolerance (CMI), but its pathogenesis is unknown. AIMS: To evaluate the histology and manometry pattern in patients with food intolerance-related constipation. PATIENTS AND METHODS: Thirty-six consecutive children with chronic constipation were enrolled. All underwent an elimination diet and successive double-blind food challenge. All underwent rectal biopsy and anorectal manometry. RESULTS: A total of 14 patients were found to be suffering from CMI and three from multiple food intolerance. They had a normal stool frequency on elimination diet, whereas constipation recurred on food challenge. The patients with food i…
Minding the Gaps : The Role of Finnish Civil Society Organizations in the Labour Market Integration of Migrants
2021
AbstractThe growing role of civil society organizations (CSOs) in welfare service provision is sometimes portrayed as a threat to welfare state universalism in Nordic societies. In Finland, CSOs co-produce integration services alongside comprehensive official integration programmes, compensating for gaps and shortcomings in those services. We identify three “gaps”, which are (1) limited availability of services in terms of time and target group, (2) lack of direct labour market contacts and (3) limited flexibility to serve individual needs. We assess how CSOs target these gaps with their service offerings through qualitative interviews with policy implementers, CSO workers and migrants. How…
Circular Dichroism of DNA G-Quadruplexes: Combining Modeling and Spectroscopy To Unravel Complex Structures
2016
We report on the comparison between the computational and experimental determination of electronic circular dichroism spectra of different guanine quadruplexes obtained from human telomeric sequences. In particular the difference between parallel, antiparallel, and hybrid structures is evidenced, as well as the induction of transitions between the polymorphs depending on the solution environment. Extensive molecular dynamics simulations (MD) are used to probe the conformational space of the different quadruplexes, and subsequently state-of-the-art hybrid quantum mechanics/molecular mechanics (QM/MM) techniques coupled with excitonic semiempirical Hamiltonian are used to simulate the macromo…
Photorefractive detection of antiparallel ferroelectric domains in BaTiO 3 and BaTiO 3 :Co crystals
1998
An all-optical method involving one coherent beam of light and based on photorefractive wave mixing is used to reveal antiparallel ferroelectric domains in one pure, and two cobalt-doped, barium titanate crystals (BaTiO 3 ). Rod-shaped domains with square cross sections are revealed.
Columnar phases from semi-discoid molecules. Phase induction via hydrogen bonding and charge transfer interactions
1991
Abstract To investigate the non-linear optical properties of nitrophenylhydrazones, a series of 4-nitro- and 2,4-dinitrophenylhydrazones of substituted aromatic aldehydes were synthesized. It was found that many of the dinitrophenythydrazone derivatives are liquid-crystalline and X-ray investigations show that the mesophase corresponds to a hexagonal columnar structure. To explain this unusual behaviour it is necessary to assume that a mesogenic structure is formed by intramolecular hydrogen bonding of the dinitrophenylhydrazones. Charge transfer induced antiparallel alignment of these moleculer dipoles leads to discoid structures, forming the columnar phases.
Analysis of multipactor RF breakdown in a waveguide containing a transversely magnetized ferrite
2016
In this paper, the multipactor RF breakdown in a parallel-plate waveguide partially filled with a ferrite slab magnetized normal to the metallic plates is studied. An external magnetic field is applied along the vertical direction between the plates in order to magnetize the ferrite. Numerical simulations using an in-house 3-D code are carried out to obtain the multipactor RF voltage threshold in this kind of structures. The presented results show that the multipactor RF voltage threshold at certain frequencies becomes considerably lower than for the corresponding classical metallic parallel-plate waveguide with the same vacuum gap
A multi-parametric evolution strategies algorithm for vehicle routing problems
2007
Vehicle routing problems are at the heart of most decision support systems for real-life distribution problems. In vehicle routing problem a set of routes must be determined at lowest total cost for a number of resources (i.e. fleet of vehicles) located at one or several points (e.g. depots, warehouses) in order to efficiently service a number of demand or supply points. In this paper an efficient evolution strategies algorithm is developed for both capacitated vehicle routing problem and for vehicle routing problem with time window constraints. The algorithm is based on a new multi-parametric mutation procedure that is applied within the 1 + 1 evolution strategies algorithm. Computational …
A multi-objective strategy for concurrent mapping and routing in networks on chip
2009
The design flow of network-on-chip (NoCs) include several key issues. Among other parameters, the decision of where cores have to be topologically mapped and also the routing algorithm represent two highly correlated design problems that must be carefully solved for any given application in order to optimize several different performance metrics. The strong correlation between the different parameters often makes that the optimization of a given performance metric has a negative effect on a different performance metric. In this paper we propose a new strategy that simultaneously refines the mapping and the routing function to determine the Pareto optimal configurations which optimize averag…
DIAGNOSTIC ACCURACY OF IXIP INDEX AND PROSTATE MRI IN THE DIAGNOSIS OF PROSTATE CANCER: PRELIMINARY RESULTS ON A COMBINED APPROACH
2021
The purpose of this study was to assess whether Immune CompleX Predictive Index (iXip) improves diagnostic accuracy of multiparametric prostate MRI (mpMRI) for clinically significant prostate cancer. This study included 72 patients (mean age: 68±8 years) with suspicion of prostate cancer and available iXip score. mpMRI images were evaluated by two radiologists according to the PI-RADS v2.1. Reference standard was based on fusion biopsy and standard transperineal 12-point biopsy. Diagnostic accuracy of iXip, mpMRI and their combination were calculated. Optimal cutoff of iXip with sensitivity and specificity was identified using the Youden index. Patients with clinically significant prostate …
Cordage, basketry and containers at the Pleistocene-Holocene boundary in southwest Europe. Evidence from Coves de Santa Maira (Valencian region, Spai…
2019
In this study we present evidence of braided plant fibres and basketry imprints on clay recovered from Coves de Santa Maira, a Palaeolithic-Mesolithic cave site located in the Mediterranean region of Spain. The anatomical features of these organic fibre remains were identified in the archaeological material and compared with modern Stipa tenacissima (esparto grass). Based on direct dating, the fragments of esparto cord from our site are the oldest worked plant fibres in Europe. Sixty fragments of fired clay are described. The clay impressions have allowed us to discuss the making of baskets and containers. According to their attributes and their functional interpretation, we have grouped th…