Search results for "Tipa"

The Wigner Distribution of Sum-of-Cissoids and Sum-of-Chirps Processes for the Modelling of Stationary and Non-Stationary Mobile Channels

2016

This paper concerns the time-frequency analysis of stationary and non-stationary multipath flat fading channels. For the modelling of stationary multipath fading channels, we use a sum-of-cisoids (SOCi) process, while the non-stationary channel is modelled by a sum-of-chirps (SOCh) process that captures the time-variant Doppler effect caused by speed variations of the mobile station. For the time-frequency analysis, we apply the concept of the Wigner distribution. Closed-form solutions are provided for the Wigner distribution of SOCi and SOCh processes. It is shown that the obtained Wigner distributions can be expressed by the sum of an auto-term representing the true Doppler power spectral…

Thermal localizable entanglement in a simple multipartite system

2009

The quantum correlations present in a system of three coupled spins 12 in a thermal state are investigated. Localizable entanglement, as well as concurrence function, is exactly evaluated. The results obtained show the existence of a temperature range corresponding to which it is impossible to localize entanglement.

Phase transitions in thin films with competing surface fields and gradients.

2011

As a generic model for phase equilibria under confinement in a thin-film geometry in the presence of a gradient in the field conjugate to the order parameter, an Ising-lattice gas system is studied by both Monte Carlo simulations and a phenomenological theory. Choosing an $L\ifmmode\times\else\texttimes\fi{}L\ifmmode\times\else\texttimes\fi{}D$ geometry with $L\ensuremath{\gg}D$ and periodic boundary conditions in the $x,y$ directions, we place competing surface fields on the two $L\ifmmode\times\else\texttimes\fi{}L$ surfaces. In addition, a field gradient $g$ is present in the $z$ direction across the film, in competition with the surface fields. At temperatures $T$ exceeding the critical…

A Non-Stationary Mobile-to-Mobile Channel Model Allowing for Velocity and Trajectory Variations of the Mobile Stations

2017

In mobile-to-mobile (M2M) communication systems, both the transmitter and the receiver are moving with a certain velocity, which is usually assumed to be constant over time. However, in realistic propagation scenarios, the velocity of the mobile stations (MSs) is subject to changes resulting in a non-stationary fading process. In this paper, we develop a non-stationary narrow-band M2M multipath fading channel model, where the transmitter and the receiver experience changes in their velocities and trajectories. For this model, we derive expressions for the local autocorrelation function (ACF), the Wigner-Ville spectrum, the local average Doppler shift, and the local Doppler spread under isot…

Master equation for cascade quantum channels: a collisional approach

2012

It has been recently shown that collisional models can be used to derive a general form for the master equations which describe the reduced time evolution of a composite multipartite quantum system, whose components "propagate" in an environmental medium which induces correlations among them via a cascade mechanism. Here we analyze the fundamental assumptions of this approach showing how some of them can be lifted when passing into a proper interaction picture representation.

Secondary Structure-Driven Self-Assembly of Thiol-Reactive Polypept(o)ides

2021

Secondary structure formation differentiates polypeptides from most of the other synthetic polymers, and the transitions from random coils to rod-like α-helices or β-sheets represent an additional parameter to direct self-assembly and the morphology of nanostructures. We investigated the influence of distinct secondary structures on the self-assembly of reactive amphiphilic polypept(o)ides. The individual morphologies can be preserved by core cross-linking via chemoselective disulfide bond formation. A series of thiol-responsive copolymers of racemic polysarcosine-block-poly(S-ethylsulfonyl-dl-cysteine) (pSar-b-p(dl)Cys), enantiopure polysarcosine-block-poly(S-ethylsulfonyl-l-cysteine) (pSa…

DIAGNOSTIC ACCURACY OF IXIP INDEX AND PROSTATE MRI IN THE DIAGNOSIS OF PROSTATE CANCER: PRELIMINARY RESULTS ON A COMBINED APPROACH

2021

The purpose of this study was to assess whether Immune CompleX Predictive Index (iXip) improves diagnostic accuracy of multiparametric prostate MRI (mpMRI) for clinically significant prostate cancer. This study included 72 patients (mean age: 68±8 years) with suspicion of prostate cancer and available iXip score. mpMRI images were evaluated by two radiologists according to the PI-RADS v2.1. Reference standard was based on fusion biopsy and standard transperineal 12-point biopsy. Diagnostic accuracy of iXip, mpMRI and their combination were calculated. Optimal cutoff of iXip with sensitivity and specificity was identified using the Youden index. Patients with clinically significant prostate …

2012

Diazepinomicin is a dibenzodiazepine alkaloid with an unusual structure among the known microbial metabolites discovered so far. Diazepinomicin was isolated from the marine sponge-associated strain Micromonospora sp. RV115 and was identified by spectroscopic analysis and by comparison to literature data. In addition to its interesting preclinical broad-spectrum antitumor potential, we report here new antioxidant and anti-protease activities for this compound. Using the ferric reducing antioxidant power (FRAP) assay, a strong antioxidant potential of diazepinomicin was demonstrated. Moreover, diazepinomicin showed a significant antioxidant and protective capacity from genomic damage induced …

The interaction of recombinant subdomains of the procollagen C-proteinase with procollagen I provides a quantitative explanation for functional diffe…

2006

The procollagen C-proteinase (PCP) is a zinc peptidase of the astacin family and the metzincin superfamily. The enzyme removes the C-terminal propeptides of fibrillar procollagens and activates other matrix proteins. Besides its catalytic protease domain, the procollagen C-proteinase contains several C-terminal CUB modules (named after complement factors C1r and C1s, the sea urchin UEGF protein, and BMP-1) and EGF-like domains. The two major splice forms of the C-proteinase differ in their overall domain composition. The longer variant, termed mammalian tolloid (mTld, i.e., PCP-2), has the protease- CUB1-CUB2-EGF1-CUB3-EGF2-CUB4-CUB5 composition, whereas the shorter form termed bone morphog…

Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Frac…

2014

In this paper, we report new protease inhibitory activity of plakortide E towards cathepsins and cathepsin-like parasitic proteases. We further report on its anti-parasitic activity against Trypanosoma brucei with an IC50 value of 5 mu M and without cytotoxic effects against J774.1 macrophages at 100 mu M concentration. Plakortide E was isolated from the sponge Plakortis halichondroides using enzyme assay-guided fractionation and identified by NMR spectroscopy and mass spectrometry. Furthermore, enzyme kinetic studies confirmed plakortide E as a non-competitive, slowly-binding, reversible inhibitor of rhodesain.