Search results for "Titi"
showing 10 items of 6322 documents
Social Media as Platform for Stimulating Urban Changes
2016
Images have always been an important part of city planning – current images of place, images with planned improvements, maps and sketches. Some time ago all that was a private property of stakeholders like planner and client. But nowadays this confidentiality rather much has vanished – no copyrights or competition is noteworthy. Plans do not have their privacy anymore. They are exposed even before they got implemented. This article will display why city planners share the images of their ideas, of their dreams in public (mostly in blogs and social networks) – why it is important for them and what kind of feedback they are waiting for. This article is based on case study where 12 respondents…
Does goal orientation relate to changes in sports club participation from adolescence to early adulthood?
2022
Background Sports club participation begins to decrease in adolescence. There is a lack of knowledge, how sports club participation changes from adolescence to early adulthood in Finland, and how goal orientation influences on it. Therefore, the aim of this study is to examine if goal orientation is associated to changes in sports club participation during afore mentioned critical years. Methods The study design is longitudinal. A sample of 366 (140 boys, 226 girls) adolescents were followed from age 15 (year 2014) to age 19 (year 2018). Sports club participation (yes/no) and goal orientation (no competitive goal, sports for hobby or physical development/regional, national or international …
Säädytöntä ja miesmäistä
2019
Frequency and Density-Dependent Selection on Life-History Strategies - A Field Experiment
2008
Negative frequency-dependence, which favors rare genotypes, promotes the maintenance of genetic variability and is of interest as a potential explanation for genetic differentiation. Density-dependent selection may also promote cyclic changes in frequencies of genotypes. Here we show evidence for both density-dependent and negative frequency-dependent selection on opposite life-history tactics (low or high reproductive effort, RE) in the bank vole (Myodes glareolus). Densitydependent selection was evident among the females with low RE, which were especially favored in low densities. Instead, both negative frequency-dependent and density-dependent selection were shown in females with high RE…
The Effect of Predator Population Dynamics on Batesian Mimicry Complexes.
2022
Understanding Batesian mimicry is a classic problem in evolutionary biology. In Batesian mimicry, a defended species (the model) is mimicked by an undefended species (the mimic). Prior theories have emphasized the role of predator behavior and learning as well as evolution in model-mimic complexes but have not examined the role of population dynamics in potentially governing the relative abundances and even persistence of model-mimic systems. Here, we examined the effect of the population dynamics of predators and alternative prey on the prevalence of warning-signaling prey composed of models and mimics. Using optimal foraging theory and signal detection theory, we found that the inclusion …
The impact of summertime food consumption by vendace on the abundance of zooplankton the following spring
2008
Desarrollo de una metodología de implantación de sistemas de vigilancia tecnológica e inteligencia competitiva en la gestión de organizaciones hotele…
2023
El propósito de esta tesis doctoral es conocer si la vigilancia tecnológica y la inteligencia competitiva es un recurso y/o una capacidad clave para la dirección estratégica en las organizaciones hoteleras, así como desarrollar un sistema normalizado de vigilancia tecnológica e inteligencia competitiva que permita incorporar un instrumento práctico de vigilancia de mercados, que mejore la toma de decisiones en la dirección estratégica de los establecimientos hoteleros. Este nuevo instrumento normalizado se diseña incorporando elementos de fuentes externas e internas, variables de vigilancia de mercados, clientes, destinos y productos aportando tres bloques de indicadores ponderados al aplic…
New developments in the management of hepatitis C virus infection: focus on boceprevir
2012
Chronic hepatitis C virus infection is an important public health problem, and the standard treatment (combination of pegylated interferon-α and ribavirin) has an effectiveness rate of only 40%-50%. Novel virus-specific drugs have recently been designed, and multiple compounds are under development. The approval for the clinical use of direct-acting antivirals in 2011 (boceprevir [BOC] and telaprevir, viral NS3 protease inhibitors) has increased recovery rates by up to 70%. Therefore, a highly effective treatment has been envisioned for the first time. This paper focuses on BOC and the implementation of new BOC-based treatment regimes.
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
The effect of carvacrol on enteric viruses.
2014
Carvacrol, a monoterpenic phenol, is said to have extensive antimicrobial activity in a wide range of food spoilage or pathogenic fungi, yeast and bacteria. The aim of this study was to assess its antiviral activity on norovirus surrogates, feline calicivirus (FCV), murine norovirus (MNV), and hepatitis A virus (HAV), as well as its potential in food applications. Initially, different concentrations of carvacrol (0.25, 0.5, 1%) were individually mixed with each virus at titers of ca. 6-7 log TCID50/ml and incubated 2h at 37°C. Carvacrol at 0.5% completely inactivated the two norovirus surrogates, whereas 1% concentration was required to achieve ca. 1 log reduction of HAV. In lettuce wash wa…