Search results for "Tobacco"
showing 10 items of 323 documents
Tobacco Use Documenting Policy and Its Association With Pupils’ Smoking and Their Perception of the Enforcement of School Smoking Bans in Finland
2014
Finnish national data sets on schools (N = 496) and pupils (N = 74,143; 14–16 years) were used to study whether a systematic documenting policy for the violations of school smoking bans was associated with pupils’ smoking and their perceptions on the enforcement of smoking bans. Attending a school with a systematic documenting policy was associated with perceptions that smoking is prohibited and restrictions monitored, with lower levels of smoking in the vicinity of the school during the school day, but not with smoking prevalence. Findings suggest that a consistent documenting policy could be an effective tool for reducing pupils’ smoking in schools.
Beclomethasone dipropionate and formoterol reduce oxidative/nitrosative stress generated by cigarette smoke extracts and IL-17A in human bronchial ep…
2013
Interleukin-17A (IL-17A), cigarette smoke and oxidative/nitrosative stress are involved in inflammatory airway diseases, and the mechanisms behind these processes are still poorly understood. We investigated whether recombinant human IL-17A (rhIL-17A), in combination with cigarette smoke extracts (CSE), increases the levels of inducibile nitric oxide synthase (iNOS), reactive oxygen species, nitrotyrosine (NT) and the activation of signal transducer and activator of transcription 1 (STAT-1) in normal human bronchial epithelial cells (16HBE). The effect of beclomethasone dipropionate (BDP), formoterol and their combination was also evaluated. We demonstrated that rhIL-17A or CSE alone increa…
Expression of a reporter gene is reduced by a ribozyme in transgenic plants
1994
A chimeric gene encoding a ribozyme under the control of the cauliflower mosaic virus (CaMV) 35S promoter was introduced into transgenic tobacco plants. In vivo activity of this ribozyme, which was designed to cleave npt mRNA, was previously demonstrated by transient expression assays in plant protoplasts. The ribozyme gene was transferred into transgenic tobacco plants expressing an rbcS-npt chimeric gene as an indicator. Five double transformants out of sixteen exhibited a reduction in the amount of active NPT enzyme. To measure the amount of ribozyme produced, in the absence of its target, the ribozyme and target genes were separated by genetic segregation. The steady-state concentration…
Uzņēmējdarbības paplašināšana starptautiskā līmenī: zīmola veidošanas procesi un kompānijas "British American Tobacco" zīmola stratēģijas
2018
Globālo tirgu raksturo vairāki vietējie un starptautiskie produkti, kas nemitīgi cīnās par vietu un lietotāju atzinību, tāpēc nevar novērtēt par zemu globālās zīmolu popularizēšanas nozīmi. Uzņēmumiem ir jāreklamē savi produkti globālā mērogā, izmantojot dažādus efektīvus mediju un izplatīšanas kanālus. Jāuzver, ka dažādus kanālus izmanto uzņēmumi, kas iziet starptautiskajos tirgos, kas, savukārt, ir noteicis globālās zīmolu popularizēšanas stratēģijas, kas ir spēkā uzņēmumā. Kad uzņēmumi izlemj paplašināties starptautiskā līmenī, izvēloties tirgus stratēģijas, būtiska loma ir standartizācijai un adaptācijai. Tad rodas jautājums, kā uzņēmumi kontrolē un uzrauga zīmola veidošanas procesus da…
First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology
2020
Wastewater-based epidemiology (WBE) has become a very useful tool to monitor a population's drug consumption or exposure to environmental and food contaminants. In this work, WBE has been applied to estimate tobacco consumption in seven Spanish regions. To this end, 24 h composite wastewater samples were taken daily for one week in 17 wastewater treatment plants, covering altogether a population of ca. 6 million inhabitants. The samples were treated by enzymatic deconjugation and the wastewater content of two human-specific nicotine metabolites (namely, cotinine and trans-3′-hydroxycotinine) was measured to estimate the daily consumption of nicotine. The population-weighted average nicotine…
Cadmium availability at different soil pH to transgenic tobacco overexpressing ferritin
2003
International audience; Knowledge on physiological mechanisms and plant metabolism can be used to enhance metal uptake. The capacity to uptake metals of transgenic tobaccos overexpressing ferritin in plastids (P6) or in cytoplasm (C5) and a control tobacco (A) is assessed in three polluted soils from the same soil series, with a similar Cd content, but displaying pH from 5.8 to 7 (8b2, 8b3, S11). Differences in dry leave weight were not significant between the three tobaccos growing on each soil. Iron concentration in ferritin overexpression either in P6 or in C5 tobaccos increased only on the S11 soil, which had a soil pH 7, in comparison to A tobacco. In both 8b2 and 8b3 soils at pH lower…
Rôle de la Dynamique Membranaire dans la Mise en Place des Mécanismes de Défense chez le Tabac
2011
Cryptogein, a protein secreted by the oomycete Phytophthora cryptogea, induces defense mechanisms in tobacco. Several proteins involved in the associated signaling pathway were identified and localized on the plasma membrane (PM). A fraction resistant to solubilization by detergent named DIMs for Detergent Insoluble Membranes, enriched in sterols an sphigolipids had been isolated from tobacco PM. It was proved to contain proteins previously identified as actors of the signaling cascade triggered by cryptogein. In animal cells, the dynamic association of proteins to sterol and sphingolipid rich microdomains under the influence of a biological stimulus plays an essential role in the regulatio…
Cryptogein treatment stimulates clathrin-endocytosis correlated with ROS production in tobacco cells
2007
International audience; During plant pathogen interactions, specific molecules elicit defense response of plant cells. Cryptogein, an elicitin produced by the pathogenic fungus Phytophtora cryptogea, induces a hypersensitive response (HR) in tobacco plants. The mode of action for cryptogein starts with recognition of this elicitor by an unidentified plasma membrane (PM) receptor. This ligand-receptor binding trigger a cascade of events at the PM level including rapid calcium influx, ions effluxes, extracellular medium alcalinization and plasma membrane depolarization both in tobacco plants and suspension cells. These events lead to the activation of plasma membrane-bound NADPH oxidase, Ntrb…
Kilka uwag o alkoholu i tytoniu w życiu żołnierzy polskich w XVII w. i w pierwszej połowie XVIII w
2017
For centuries alcohol had constituted a key component of soldiers’ diet. As early as in ancient times, health benefits of wine and its impact on human body were appreciated, foremostly its germicidal properties. Probably alcohol was popular among soldier of the first Piasts or knight of the time of regional disintegration, time of king Władysław 1 the Elbow-high, Casimir the Great or kings of the Jagiellonian dynasty. It may be presumed that the former only drank beer, however, knights in XIV-XV treated it as a common everyday beverage, relishing wine for special occassions and during feasts. In XVI century the list of alcoholic beverages was enriched by vodka - aqua vitae. In the first hal…
Association between Asthma Control and Exposure to Greenness and Other Outdoor and Indoor Environmental Factors: A Longitudinal Study on a Cohort of …
2022
Achieving and maintaining asthma control (AC) is the main goal of asthma management. Indoor and outdoor environmental factors may play an important role on AC. The aim of this longitudinal study was to evaluate the association between AC and exposure to greenness and other outdoor or indoor environmental factors in a cohort of asthmatic children. This study involved 179 asthmatic children (5–16 years). Parents were interviewed through a modified version of the SIDRIA questionnaire. AC was assessed at each visit. Exposure to greenness was measured using the normalized difference vegetation index (NDVI). A logistic regression model was applied for assessing risk factors for uncontrolled…