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showing 10 items of 2844 documents

Metformin and health outcomes:An umbrella review of systematic reviews with meta-analyses

2021

Background:\ud \ud The objective was to capture the breadth of outcomes that have been associated with metformin use and to systematically assess the quality, strength and credibility of these associations using the umbrella review methodology.\ud \ud Methods:\ud \ud Four major databases were searched until 31 May 2020. Meta‐analyses of observational studies and meta‐analyses of randomized controlled trials (RCTs) (including active and placebo control arms) were included.\ud \ud Results:\ud \ud From 175 eligible publications, we identified 427 different meta‐analyses, including 167 meta‐analyses of observational studies, 147 meta‐analyses of RCTs for metformin vs placebo/no treatment and 11…

MaleGRADE meta-analysis metformin umbrellamedicine.medical_specialtyPregnancy Rateendocrine system diseasesClinical Biochemistry030204 cardiovascular system & hematologyOverweightBiochemistryBody Mass Indexlaw.invention03 medical and health sciences0302 clinical medicineMeta-Analysis as TopicRandomized controlled trialPregnancylawNeoplasmsInternal medicinemedicineHumansHypoglycemic AgentsObesity030212 general & internal medicinePrediabetesbusiness.industryGeneral MedicineOverweightProtective Factorsmedicine.diseaseMetforminMetforminDiabetes Mellitus Type 1Systematic reviewDiabetes Mellitus Type 2Cardiovascular DiseasesMeta-analysisFemaleObservational studymedicine.symptombusinessInfertility FemaleBody mass indexPolycystic Ovary SyndromeSystematic Reviews as Topicmedicine.drug
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Quality of life in patients with bladder cancer undergoing ileal conduit: A comparison of women versus men

2018

Background/Aim: Studies comparing health-related quality of life (HR-QoL) between patients who underwent radical cystectomy (RC) and those who underwent a different form of urinary diversion has not reached yet univocal and reliable conclusions. The aim of our study was to evaluate bladder-specific long-term HR-QoL after radical cystectomy and ileal conduit. Patients and Methods: A multicenter study was carried out on 145 consecutive patients (112 males and 33 females) undergoing RC and ileal conduit (IC). HR-QoL assessment was conducted using Italian versions of European Organisation for Research and Treatment of Cancer QLQ-C30 and EORTC BLM-30 questionnaires. Results: Our data showed that…

MaleGenetics and Molecular Biology (all)Cancer Researchmedicine.medical_treatment030232 urology & nephrologySex FactorUrinary DiversionBiochemistrySettore MED/24 - UrologiaBladder cancer; ileal conduit; quality of life; Orthotopic neobladder0302 clinical medicineQuality of lifeSurveys and QuestionnairesOutcome Assessment Health CareOrthotopic neobladderSurveys and QuestionnaireUrinary bladderSettore MED/24 - UROLOGIABladder cancerMiddle AgedhumanitiesBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Biochemistry Genetics and Molecular Biology (all); Pharmacologymedicine.anatomical_structureIleal conduit030220 oncology & carcinogenesisUrinary Bladder NeoplasmFemaleResearch ArticleHumanQuality of lifemedicine.medical_specialtyBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Aged; Female; Humans; Male; Middle Aged; Outcome Assessment (Health Care); Sex Factors; Surveys and Questionnaires; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Diversion; Quality of Life; Biochemistry Genetics and Molecular Biology (all); PharmacologyUrinary BladderGeneral Biochemistry Genetics and Molecular BiologyCystectomy03 medical and health sciencesOutcome Assessment (Health Care)Sex FactorsInternal medicinemedicineHumansIn patientAgedPharmacologyBladder cancerBiochemistry Genetics and Molecular Biology (all)business.industryUrinary diversionCancermedicine.diseaseRadical cystectomyUrinary Bladder NeoplasmsBladder cancer; ileal conduit; orthotopic neobladder; quality of life; radical cystectomybusinessSexual function
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Motives for and barriers to physical activity among older adults with mobility limitations

2007

The purpose of this study was to investigate what older adults with severe, moderate, or no mobility limitation consider motives for and barriers to engaging in physical exercise. Community-dwelling adults (N = 645) age 75–81 years completed a questionnaire about their motives for and barriers to physical exercise and answered interview questions on mobility limitation. Those with severely limited mobility more often reported poor health, fear and negative experiences, lack of company, and an unsuitable environment as barriers to exercise than did those with no mobility limitation. They also accentuated disease management as a motive for exercise, whereas those with no or moderate mobility …

MaleGerontologyAgingActivities of daily livingFrail ElderlyPhysical activityPhysical Therapy Sports Therapy and RehabilitationPhysical exerciseMotor ActivityInterviews as TopicActivities of Daily LivingHumansMobility LimitationDisease management (health)Exercise physiologyExerciseGeriatric AssessmentAgedAged 80 and overRehabilitationAge FactorsHealth SurveysHealth promotionMobility LimitationFemaleSupport systemGeriatrics and GerontologyPsychologyGerontologySocial psychology
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Lived experiences of self-care among older physically active urban-living individuals

2013

- Published article -cc-by-nc Background: Promoting physical activity is a public health priority in most industrial countries, and physical function is an important factor when taking into consideration older people’s self-care and health. Despite the increasing challenges associated with urbanization and the aging population, urban life appears to be positive in many ways for urban dwellers. However, the manner in which older people live in urban settings and how this influences their ability to take care of themselves should be considered important knowledge for health professionals and politicians to acquire. The aim of this study was to describe the lived experiences of self-care and f…

MaleGerontologyAgingPopulation ageingmedicine.medical_specialtyUrban Populationhealth promotionHealth StatusSocial Environmentperceived healthPhenomenology (archaeology)Interviews as TopicUrbanizationmedicineHumansMobility LimitationExerciseOriginal ResearchAged 80 and overNorwaybusiness.industryLived experiencePublic healthVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778Social environmentVDP::Medical disciplines: 700::Health sciences: 800General MedicinePeer reviewSelf CareagedHealth promotionClinical Interventions in AgingphenomenologyFemaleGeriatrics and Gerontologybusiness
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An Expert Opinion From the European Society of Hypertension–European Union Geriatric Medicine Society Working Group on the Management of Hypertension…

2016

Two years after the publication of the 2013 guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC),1 the ESH and the European Union Geriatric Medicine Society have created a common working group to examine the management of hypertensive subjects aged >80 years. The general term hypertension in the elderly is not sufficiently accurate because it mixes younger old patients (60–70 years) with the oldest old. Our group believes that the management of hypertension in individuals aged ≥80 years should be specifically addressed. Although arbitrary, this cutoff value identifies a population that is expanding …

MaleGerontologyBLOOD-PRESSUREL-ARGININE TRANSPORTFAT-FED RABBITS030204 cardiovascular system & hematologySeverity of Illness IndexSYMPATHETIC-NERVE ACTIVITY0302 clinical medicine80 and overPerindopril030212 general & internal medicineDisease management (health)Societies MedicalComputingMilieux_MISCELLANEOUSMETABOLIC SYNDROMEmedia_commonAged 80 and overGeriatricseducation.field_of_study[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyIndapamideDisease ManagementPrognosis[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system3. Good healthAntihypertensive AgentTreatment OutcomeHypertensionPractice Guidelines as TopicFemaleSurvival AnalysiHumanmedicine.drugANGIOTENSIN-CONVERTING ENZYMEmedicine.medical_specialtyPrognosiFrail ElderlyeducationPopulationRisk Assessment03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemMedicalInternal MedicinemedicineHumansmedia_common.cataloged_instanceEuropean UnionNITRIC-OXIDE SYNTHASEEuropean unioneducationREDUCES OXIDATIVE STRESSExpert TestimonyGeriatric AssessmentAntihypertensive AgentsAgedAged; Aged 80 and over; Antihypertensive Agents; Blood Pressure Determination; Disease Management; European Union; Expert Testimony; Female; Frail Elderly; Geriatric Assessment; Geriatrics; Humans; Hypertension; Male; Prognosis; Risk Assessment; Severity of Illness Index; Societies Medical; Survival Analysis; Treatment Outcome; Practice Guidelines as Topic; Internal Medicinebusiness.industryBlood Pressure DeterminationSurvival AnalysisBlood pressureOBESITY-INDUCED HYPERTENSIONGeriatrics3121 General medicine internal medicine and other clinical medicineENDOTHELIAL DYSFUNCTIONLife expectancySocietiesbusinessGeriatric[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyHypertension
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Being hospitalized with a newly diagnosed chronic illness - A phenomenological study of children’s lifeworld in the hospital

2012

The impact of a hospital environment on children has rarely been investigated. Recently, however, the perspective of hospitalized children has been taken into account. Being hospitalized and facing an illness represent a dramatic change in a child’s daily life, and the quality of the environment may influence the child’s experiences. The aim of this study was to investigate the experiences of children being hospitalized with newly diagnosed type 1 diabetes and to obtain an increased understanding of the environmental influences on the children’s lifeworld. The study used a hermeneutic phenomenological approach. The design is a combination of observation of the participant, interviews, and p…

MaleGerontologyHealth Knowledge Attitudes Practicemedicine.medical_specialtyLifeworldtype 1 diabetesmedia_common.quotation_subjectNewly diagnosedNursingbodily changeshospital environmentInterviews as TopicVDP::Medical disciplines: 700::Health sciences: 800::Nursing science: 808Empirical StudiesPerceptionAdaptation PsychologicalVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Pediatrics: 760HumansLearningMedicineChildPsychiatrymedia_commonEnvironment method hospitalised children lived experience type 1 diabetesbusiness.industryHealth PolicyLived experiencePerspective (graphical)Peer reviewIssues ethics and legal aspectsAlertnessDiabetes Mellitus Type 1hermeneutic phenomenological methodChronic DiseaseHealth Facility Environmentlived experienceFemaleFundamentals and skillsHospitalized childrenThematic analysisbusinessChild HospitalizedGerontologyInternational Journal of Qualitative Studies on Health and Well-being
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How individuals with dementia in nursing homes maintain their dignity through life storytelling - A case study

2015

Aims and objectives: The aim of this article was to present and discuss findings on what individuals with dementia do by themselves to maintain or promote their dignity of identity when they live in a nursing home. Background: The majority of residents living in Norwegian nursing homes suffer from dementia. Individuals who suffer from dementia are particularly vulnerable, and their dignity of identity is at risk. It is therefore of great importance to explore how we can maintain their dignity of identity. Design: The study builds on a phenomenological and hermeneutic design. Methods: The article reports three cases or life stories based on participant observation in two different nursing hom…

MaleGerontologyHealth Services for the Agedmedia_common.quotation_subjectNursing homeslife storytellingInterviews as TopicDignityNarrativeNursingIdentitymental disordersmedicineLife-story tellingHumansDementiaNarrativeGeneral NursingAgedmedia_commonNarrationbusiness.industryGeneral Medicinemedicine.diseasenursing homeFemaleDementiaNursing homesbusinessDignityStorytellingClinical nursing
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The Norwegian Healthy Life Study: protocol for a pragmatic RCT with longitudinal follow-up on physical activity and diet for adults

2017

The Norwegian Directorate of Health recommends that Healthy Life Centres (HLCs) be established in primary health care to support behaviour change and reduce the risk of non-communicable diseases. The aim of the present study protocol is to present the rationale, design and methods of a combined pragmatic randomized controlled trial (RCT) and longitudinal cohort study of the effects of attending HLCs concerning physical activity, sedentary behaviour and diet and to explore how psychological well-being and motivational factors may mediate short— and long-term effects. The present study will combine a 6-month RCT with a longitudinal cohort study (24 months from baseline) conducted at six HLCs …

MaleGerontologyResearch designHealth BehaviorPsychological interventionlaw.inventionStudy Protocol0302 clinical medicineRandomized controlled trialBehavior TherapylawHealth care030212 general & internal medicineNorwayCommunicationlcsh:Public aspects of medicineMental HealthResearch DesignFemaleDiet Healthy0305 other medical scienceAdultRiskRandomized control trialmedicine.medical_specialtyHealth Promotion03 medical and health sciencesQuality of life (healthcare)Patient Education as TopicmedicineHumansAdultsExerciseLife StyleMotivation030505 public healthPrimary Health Carebusiness.industryPhysical activityPublic healthPublic Health Environmental and Occupational Healthlcsh:RA1-1270DietHealth promotionQuality of LifePhysical therapyHealth behaviourbusinessRisk Reduction BehaviorFollow-Up StudiesPatient educationBMC Public Health
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Nutritional self-care in two older Norwegian males: a case study

2013

Solveig T Tomstad,1,2 Ulrika Söderhamn,2 Geir Arild Espnes,1,3 Olle Söderhamn21Department of Social Work and Health Science, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology, Trondheim, 2Centre for Caring Research-Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, 3Research Centre for Health Promotion and Resources, Department of Social Work and Health Science, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology, Trondheim, NorwayBackground: Knowledge about how to support nutritional self-care in the vulnerable elderly living in their own …

MaleGerontologyhealth promotionHealth StatustverrsnittkartleggingSASEAppraisal of Self-care Agency scaleSurveys and QuestionnairesStudy circleegenomsorgsevneMedicineernæringsstatusinterventionOriginal ResearchdrikkemåltidegenomsorgNorwayNutritional Supportopplevelse av sammenhengGeneral MedicineunderernæringSelf-care Ability Scale for the ElderlyPeer reviewstudiesirkellanguageIndependent Livingstudy circleSense of CoherenceeducationhjemmeboendeNorwegianNorgeVulnerable PopulationselderlyNutritional Form For the ElderlyforebyggingInterviews as TopicmathelsefremmingNursingNUFFEIntervention (counseling)eldreHumansSOCGeriatric AssessmentAgedopplevelsepasientsikkerhetlivskvalitetbusiness.industrycasestudierisikoGeriatric assessmentlanguage.human_languagehelseSelf CareHealth promotionClinical Interventions in AgingSelf careGeriatrics and GerontologybusinessIndependent livingernæringintervensjonClinical Interventions in Aging
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The unfortunate generation: stroke survivors in Riga, Latvia

2003

Abstract The poor health status of citizens in post-Soviet states has been reported but few studies have investigated the illness experiences of people in those countries. This paper reports findings from an interview study conducted with stroke patients in Riga, Latvia, who were part of a cohort recruited over 1 year for a European study comparing the provision of care, outcomes and resource use. The interview study aimed to elicit stroke patients’ own perceptions of the impact of stroke 1 year after the event. Adopting a phenomenological perspective we illustrate how the particular social setting shapes stroke as an illness, its influences on access to health care and on consideration of …

MaleGerontologymedicine.medical_specialtyHealth (social science)HistoryContext (language use)Health Services AccessibilityCohort StudiesInterviews as TopicLife Change EventsHistory and Philosophy of ScienceSickness Impact ProfileActivities of Daily LivingHealth caremedicineHumansDisabled PersonsSurvivorsSocial ChangeStrokeQualitative ResearchAgedAged 80 and overPovertybusiness.industryPublic healthStroke RehabilitationSocial SupportLatvianMiddle Agedmedicine.diseaseLatvialanguage.human_languageStrokeCohortlanguageFemaleHealth ExpendituresBasic needsbusinessAttitude to HealthDemographySocial Science & Medicine
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