Search results for "Toxic"

showing 10 items of 6968 documents

Synthesis and properties of a photoaffinity labeling reagent for protoporphyrinogen oxidases, the target enzymes of diphenyl ether herbicides

1994

A diazoketone 3 has been synthesized in two steps from acifluorfen 1, a diphenyl ether herbicide. Like the parent compound 1, the diazoketone 3 is toxic to plant cells and inhibits protoporphyrinogen oxidase, the molecular target of diphenyl ether herbicides. On photolysis of 3 in methanol, the generated carbene mainly undergoes the Wolff rearrangement to a ketene which further adds methanol, but many other products are observed. A tritiated derivative of 3 has been prepared which is suitable for photoaffinity labeling experiments.

0106 biological sciencesOxidoreductases Acting on CH-CH Group Donors[SDV]Life Sciences [q-bio]Clinical BiochemistryPharmaceutical ScienceKeteneAcifluorfen01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compoundDrug DiscoveryOrganic chemistryProtoporphyrinogen OxidaseMolecular BiologyComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesPhotolysisPhotoaffinity labelingMolecular StructureBIOCHIMIEHerbicidesOrganic ChemistryDiphenyl etherWolff rearrangementAffinity Labels[SDV] Life Sciences [q-bio]chemistryTOXICOLOGIEReagentMolecular MedicineProtoporphyrinogen oxidaseIndicators and ReagentsMethanolSoybeansOxidoreductases010606 plant biology & botany
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Phosphoproteins Involved in the Signal Transduction of Cryptogein, an Elicitor of Defense Reactions in Tobacco

2000

We previously reported that the signal transduction of cryptogein, an elicitor of defense reactions in Nicotiana tabacum cells, involves upstream protein phosphorylation. In the present study, induction of these early physiological events was further investigated with inhibitors of protein phosphatase (PP), okadaïc acid, and calyculin A. Calyculin A mimicked the effects of cryptogein, inducing an influx of calcium, an extracellular alkalinization, and the production of active oxygen species (AOS), suggesting that during cryptogein signal transduction the balance between specific protein kinase (PK) and PP activities was modified. To identify the phosphorylated proteins that could be involv…

0106 biological sciencesPhysiologyPhosphataseBiology01 natural sciencesFungal Proteins03 medical and health scienceschemistry.chemical_compound[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]TobaccoPhosphoprotein Phosphatasesmedicine[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyStaurosporineProtein phosphorylationEnzyme InhibitorsPhosphorylationProtein Kinase InhibitorsComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesFungal proteinIon TransportAlgal ProteinsGeneral MedicinePhosphoproteinsElicitorPlants ToxicchemistryBiochemistryPhosphorylationCalciumSignal transductionAgronomy and Crop ScienceSignal Transduction010606 plant biology & botanyCalyculinmedicine.drugMolecular Plant-Microbe Interactions®
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Tomato trichomes are deadly hurdles limiting the establishment of Amblyseius swirskii Athias-Henriot (Acari: Phytoseiidae)

2021

[EN] Amblyseius swirskii is a predatory mite widely used for the control of very important pest species, such as whiteflies and thrips, in organic farming and conventional agriculture. However, this species cannot establish on tomato crops, probably due to the toxic effects of plant trichomes and their exudates. We evaluated tomato plants for effects on: a) A. swirskii preference mediated by plant volatiles, b) A. swirskii development, predation capacity and reproductive performance, c) the dispersal and survival of mites as affected by stem trichomes, and d) mite survival as a function of secondary metabolites secreted by tomato trichomes. The results showed that A. swirskii mites which ga…

0106 biological sciencesPhytoseiidaeH10 Pests of plantsBiological pest control01 natural sciencesPredationAcyl sugarsPepperhost plant defenseMiteBIOQUIMICA Y BIOLOGIA MOLECULARpredatory mitesAcariacyl sugars2. Zero hungerbiologyToxicityPredatory mitesfungifood and beveragestoxicitybiology.organism_classificationTrichome010602 entomologyHorticultureHost plant defenseInsect SciencePEST analysisAgronomy and Crop Science010606 plant biology & botany
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Proposed Environmental Risk Management Elements in a Carpathian Valley Basin, within the Roşia Montană European Historical Mining Area

2021

Non-ferrous metals mining activities have long accompanied people, and began in the study area of South East Europe over 2000 years ago. The environment quality is significantly affected by both historic mining activities and contemporary impacts. All these problems, inducing synergic negative effects on local organism communities, have created a chronic state of pollution. The Corna Valley has one of the oldest historical human impacts in Romania due to the influence of mining. Fish and benthic macroinvertebrates have exhibited significant responses to long term mining effects on lotic systems. The analysis of macroinvertebrate communities, correlated with the lack of fish and some biotope…

0106 biological sciencesPollutionBiotopehuman impactlentic and lotic ecosystemsRiver ecosystemHealth Toxicology and Mutagenesismedia_common.quotation_subject010501 environmental sciencesStructural basinrisk management01 natural sciencesArticleRiversAnimalsHumansRisk management0105 earth and related environmental sciencesmedia_commonInvertebratefishhuman impact; lentic and lotic ecosystems; aquatic macroinvertebrates; fish; threats; risk management; Corna BasinCorna BasinthreatsMontanaRomaniabusiness.industry010604 marine biology & hydrobiologyEnvironmental resource managementRPublic Health Environmental and Occupational HealthInvertebratesaquatic macroinvertebratesEuropeGeographyBenthic zoneMedicineFish <Actinopterygii>businessWater Pollutants ChemicalEnvironmental MonitoringInternational Journal of Environmental Research and Public Health
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Unexpected increases in rotifer resting egg abundances during the period of contamination of Lake Orta

2016

&lt;p&gt;Despite their ecological importance and rapid response to environmental changes, rotifers are rarely included in palaeolimnological studies. Here, we describe changes in abundance (ABD) and morphotype (MTs) diversity of rotifer resting eggs in the sediments of deep subalpine Lake Orta, Italy, covering a period prior to (pre-) 1926, during long-term ammonia and metal pollution from a rayon factory, and subsequent recovery of water quality. Following the pollution and bacterial oxidation of the ammonia, Lake Orta became the largest and deepest acid lake in Europe. Recovery of water quality followed both a ban on the discharge of industrial wastes, and a liming intervention in 1989 an…

0106 biological sciencesPollutionmedia_common.quotation_subjectta1172Copper and ammonia pollution; Diapause; Lake Orta; Paleo-ecotoxicology; Rotifera;RotiferaRotifer010501 environmental sciencesAquatic ScienceLake Orta01 natural sciencesZooplanktonAnimal sciencerataseläimetAbundance (ecology)copper and ammonia pollution.lcsh:Physical geographylcsh:Environmental sciences0105 earth and related environmental sciencesWater Science and Technologymedia_commonlcsh:GE1-350EcologybiologyEcology010604 marine biology & hydrobiologylcsh:Geography. Anthropology. RecreationBrachionusbiology.organism_classification6. Clean waterDiapausepaleo-ecotoxicologydiapausecopper and ammonia pollutionCopper and ammonia pollutionCladoceralcsh:G13. Climate actionta1181Water qualityPaleo-ecotoxicologyEutrophicationlcsh:GB3-5030
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Trophic transfer of pesticides: The fine line between predator–prey regulation and pesticide–pest regulation

2020

International audience; Understanding pesticide impacts on populations of target/non-target species and communities is a challenge to applied ecology. When predators that otherwise regulate pest densities ingest prey contaminated with pesticides, this can suppress predator populations by secondary poisoning. It is, however, unknown how species relationships and protocols of treatments (e.g. anticoagulant rodenticide [AR]) interact to affect pest regulation.To tackle this issue, we modelled a heuristic non-spatialized system including montane water voles, specialist vole predators (stoats, weasels) and a generalist predator (red fox) which consumes voles, mustelids and other prey. By carryin…

0106 biological sciencesPopulation010603 evolutionary biology01 natural sciencesPredationsensitivity analysisSecondary poisoningecological controlEcosystemeducationPredatorTrophic level2. Zero hungereducation.field_of_studyEcologybiologyEcology010604 marine biology & hydrobiologypesticides15. Life on landPesticidebiology.organism_classificationcyclic fluctuationssecondary poisoningecosystem service13. Climate actionVolebiodiversity conservation[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicologycascade effectsJournal of Applied Ecology
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Reducing the effect of beauvericin on neuroblastoma SH-SY5Y cell line by natural products

2020

Abstract In the present work, different natural compounds from coffee by-product extracts (coffee silverskin and spent coffee) rich in polyphenols, was investigated against beauvericin (BEA) induced-cytotoxicity on SH-SY5Y cells. Spent coffee arise as waste products through the production of instant coffee and coffee brewing; while the silverskin is a tegument which is removed and eliminated with toasting coffee grains. First of all, polyphenol extraction methods, measurement of total polyphenols content and its identification were carried out. Afterwards evaluating in vitro effects with MTT assay on SH-SY5Y cells of coffee by-product extracts and mycotoxins at different concentrations and …

0106 biological sciencesSH-SY5YToxicologyCoffee01 natural sciencesAntioxidantsNeuroblastoma03 medical and health scienceschemistry.chemical_compoundChlorogenic acidCell Line TumorDepsipeptidesHumansMTT assayFood scienceMycotoxinBiological Products0303 health sciencesPlant ExtractsChemistrybusiness.industry010604 marine biology & hydrobiology030302 biochemistry & molecular biologyfood and beveragesMycotoxinsBeauvericinCell culturePolyphenolBrewingbusinessToxicon
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Evaluation and comparison of trace metal accumulation in different tissues of potential bioindicator organisms: Macrobenthic filter feedersStyela pli…

2016

Trace metal concentrations were measured in different tissues of Sabella spallanzanii, Styela plicata, and Mytilus galloprovincialis collected in the Termini Imerese Harbor (Sicily, Italy) to evaluate the potential use of these species as bioindicators. Higher bioaccumulation factors (BAFs) were calculated in the tube of S. spallanzanii, except for As, which had a higher BAF in the branchial crown of the same species. Regarding the other species analyzed, higher BAFs were found in the digestive gland of M. galloprovincialis. An exception was Pb, which was significantly more concentrated in the branchial basket and tunic of S. plicata. The BAFs calculated in the present study show that all t…

0106 biological sciencesSabella spallanzaniibiologyEcology010604 marine biology & hydrobiologyHealth Toxicology and MutagenesisZoology010501 environmental sciencesbiology.organism_classification01 natural sciencesMytilusFilter (aquarium)Styela plicataFilter feedingBioaccumulationEnvironmental ChemistryTrace metalBioindicator0105 earth and related environmental sciencesEnvironmental Toxicology and Chemistry
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Silver Nanoparticles Affect Functional Bioenergetic Traits in the Invasive Red Sea Mussel Brachidontes pharaonis

2016

We investigated the functional trait responses to 5 nm metallic silver nanoparticle (AgNPs) exposure in the Lessepsian-entry bivalveB. pharaonis. Respiration rate (oxygen consumption), heartbeat rate, and absorption efficiency were evaluated across an 8-day exposure period in mesocosmal conditions. Basal reference values from not-exposed specimens were statistically compared with those obtained from animals treated with three sublethal nanoparticle concentrations (2 μg L−1, 20 μg L−1, and 40 μg L−1). Our data showed statistically significant effects on the average respiration rate ofB. pharaonis. Moreover, complex nonlinear dynamics were observed as a function of the concentration level and…

0106 biological sciencesSettore BIO/07 - EcologiaSilverArticle SubjectHeartbeatBioenergeticsImmunology and Microbiology (all)lcsh:Medicine010501 environmental sciencesEnvironment01 natural sciencesAcclimatizationGeneral Biochemistry Genetics and Molecular BiologySilver nanoparticleToxicologyMetal NanoparticleRespiratory RateHeart Rate14. Life underwaterFood science0105 earth and related environmental sciencesBiochemistry Genetics and Molecular Biology (all)General Immunology and MicrobiologybiologyAnimal010604 marine biology & hydrobiologylcsh:RGeneral MedicineMusselBivalviabiology.organism_classificationBivalviaBrachidontes pharaonisMytilidaeRespiration rateEnergy Metabolism
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Annual post-market environmental monitoring (PMEM) report on the cultivation of genetically modified maize MON 810 in 2014 from Monsanto Europe S.A.

2016

Requestor: European CommissionQuestion number: EFSA-Q-2015-00650; Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) assessed the annual post-market environmental monitoring (PMEM) report for the 2014 growing season of maize MON 810 provided by Monsanto Europe S.A. The GMO Panel concludes that the insect resistance monitoring data do not indicate a decrease in susceptibility of field Iberian populations of corn borers to the Cry1Ab protein over the 2014 season. However, as the methodology for insect resistance monitoring remained unchanged compared to previous PMEM reports, the GMO Panel reiterates …

0106 biological sciencesSettore BIO/07 - EcologiaVeterinary (miscellaneous)[SDV]Life Sciences [q-bio]TP1-1185Plant Science010501 environmental sciencesZea mays01 natural sciencesMicrobiologycase‐specific monitoringCry1Ab case-specific monitoring farmer questionnaires general surveillance insect resistance management Zea maysTX341-641Cry1Ab0105 earth and related environmental sciences2. Zero hungerNutrition. Foods and food supplyChemical technologyfungigeneral surveillance10079 Institute of Veterinary Pharmacology and Toxicologyfarmer questionnairesinsect resistance managementSettore AGR/02 - Agronomia E Coltivazioni ErbaceeSettore AGR/11 - Entomologia Generale E Applicata570 Life sciences; biologyAnimal Science and ZoologyParasitology010606 plant biology & botanyFood Science
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