Search results for "Toxic"

showing 10 items of 6968 documents

Proteomic insights into the immune response of the Colorado potato beetle larvae challenged with Bacillus thuringiensis.

2019

Bacillus thuringiensis (Bt) toxins constitute effective, environmentally safe biopesticides. Nevertheless, insects' tolerance to Bt is influenced by environmental factors affecting immunity. To understand larval immune response in the devastating coleopteran insect pest Colorado potato beetle (CPB), we undertook a proteomic analysis of hemolymph of non-treated control larvae and larvae consuming non-lethal doses of spore-crystal mixtures containing the coleopteran-active Cry3Aa toxin. Results revealed lower amount of proteins involved in insect growth and higher amount of immune response-related proteins in challenged insects, sustaining the larval weight loss observed. Additionally, we fou…

0106 biological sciences0301 basic medicinePore Forming Cytotoxic ProteinsProteomicsmedia_common.quotation_subjectImmunologyAntimicrobial peptidesBacillus thuringiensisInsect01 natural sciencesMicrobiology03 medical and health sciencesHemolysin ProteinsImmune systemBacillus thuringiensisHemolymphAnimalsGram-Positive Bacterial InfectionsSolanaceaemedia_commonLarvabiologyBacillus thuringiensis ToxinsMonophenol MonooxygenasefungiColorado potato beetleImmunitybiology.organism_classificationDietColeopteraEndotoxins010602 entomologyBiopesticideMicroRNAs030104 developmental biologyLarvaInsect ProteinsDevelopmental BiologyDevelopmental and comparative immunology
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Molecule structural factors influencing the loading of flavoring compounds in a natural-preformed capsule: Yeast cells

2016

International audience; Yeast cells are efficient microcapsules for the encapsulation of flavoring compounds. However, as they are preformed capsules, they have to be loaded with the active. Encapsulation efficiency is to a certain level correlated with LogP. In this study, the effect of structural factors on the encapsulation of amphiphilic flavors was investigated. Homological series of carboxylic acids, ethyl esters, lactones, alcohols and ketones were encapsulated into the yeast Yarrowia lipolytica. Although, in a single homological series, the length of the molecule and thus the LogP were correlated with encapsulation efficiency (EY%), big differences were observable between series. Fo…

0106 biological sciences0301 basic medicineSaccharomyces cerevisiaeCapsulesSaccharomyces-cerevisiae01 natural sciencesHexanalYeast cellDiffusion03 medical and health scienceschemistry.chemical_compoundColloid and Surface ChemistryFlavorsYeasts010608 biotechnologyAmphiphileMechanismsOrganic chemistryMoleculePhysical and Theoretical ChemistryMicroencapsulationHexanoic acidMolecular StructurebiologyToxicityMembrane[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringYarrowiaSurfaces and InterfacesGeneral Medicinebiology.organism_classificationFood ingredientsOrganic-solventsYeastFlavoring AgentsMicrocapsules030104 developmental biologyMembranechemistryFunctional groupsEncapsulationDeliveryMolecule structureBiotechnology
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Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemi…

2016

Salvia miltiorrhiza (SM) Bunge is one of the widely-used Chinese medicinal herbs. In this study, the chemical constituents and anticancer potential of SM stems and leaves were examined with those of respective callus cultures. The callus culture for stem and leaf explants was initiated in modified Murashige and Skoog (MS) medium. Active constituents of respective extracts were analyzed by high performance liquid chromatography coupled with DAD and MS (HPLC-DAD-MS). Rosmarinic acid (RA) and salvianolic acid B (Sal B) were determined to be the main phenolic compounds. Quantitative analyses revealed that callus stem extracts produced higher amount of RA and Sal B (stem RA: 1.27±0.38%; stem Sal…

0106 biological sciences0301 basic medicineSalvia miltiorrhizaBiology01 natural sciencesHigh-performance liquid chromatographySalvia miltiorrhizaDepsidesAnalytical Chemistry03 medical and health scienceschemistry.chemical_compoundCytotoxicityIC50Chromatography High Pressure LiquidBenzofuransTraditional medicinePlant ExtractsRosmarinic acidfungifood and beveragesGeneral MedicinePrecursor Cell Lymphoblastic Leukemia-LymphomaIn vitroPlant Leaves030104 developmental biologyBiochemistrychemistryCinnamatesCallus010606 plant biology & botanyFood ScienceExplant cultureDrugs Chinese HerbalFood chemistry
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First outbreak of Pepper vein yellows virus infecting sweet pepper in Italy

2016

Sweet pepper (Capsicum annum) is an economically important crop worldwide, including Sicily where about 4,000 hectares are grown each year. In October 2015, severe symptoms not previously reported by growers in the horticultural area of the province of Trapani (Sicily, Italy) were observed on sweet pepper plants in eight different greenhouses. Symptoms included upward leaf curling, internodal shortening and interveinal yellowing. Symptoms were more evident in the upper part of the plants. These symptoms were reminiscent of those caused by poleroviruses. In the greenhouse, symptoms were evident in about 35% of the plants. Three samples per greenhouse (24 in total) were collected for analysis.

0106 biological sciences0301 basic medicineSweet PeppersVeterinary medicinefood.ingredientHealth Toxicology and MutagenesisBegomoviruOutbreakSettore AGR/12 - Patologia VegetalePlant ScienceBiology01 natural sciencesVirusCropPolerovirus03 medical and health sciencesEmerging pathogen030104 developmental biologyfoodToLCNDVPlant virusBotanyPepperAgronomy and Crop Science010606 plant biology & botany
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Marine Cryptophytes Are Great Sources of EPA and DHA

2017

Microalgae have the ability to synthetize many compounds, some of which have been recognized as a source of functional ingredients for nutraceuticals with positive health effects. One well-known example is the long-chain polyunsaturated fatty acids (PUFAs), which are essential for human nutrition. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are the two most important long-chain omega-3 (-3) PUFAs involved in human physiology, and both industries are almost exclusively based on microalgae. In addition, algae produce phytosterols that reduce serum cholesterol. Here we determined the growth rates, biomass yields, PUFA and sterol content, and daily gain of eight strains of marine…

0106 biological sciences0301 basic medicineTROPICAL AUSTRALIAN MICROALGAELINOLENIC ACIDrasvahapotPharmaceutical Sciencesterols01 natural scienceschemistry.chemical_compoundFunctional FoodDrug DiscoveryFood scienceBiomasslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)functional foodsPOLYUNSATURATED FATTY-ACIDSchemistry.chemical_classificationnutraceuticalsFRESH-WATERPRODUCTIVITYbiologymicroalgae; polyunsaturated fatty acids; omega-3; omega-6; sterols; functional foods; nutraceuticalsCHOLESTEROLmicroalgaeNANNOCHLOROPSISPhytosterolsfood and beveragesEicosapentaenoic acidEicosapentaenoic AcidDocosahexaenoic acidFatty Acids Unsaturatedlipids (amino acids peptides and proteins)omega-3CryptophytaPolyunsaturated fatty acidpolyunsaturated fatty acidsDocosahexaenoic Acidsomega-6CHEMICAL-COMPOSITIONterveysvaikutteiset elintarvikkeetfatty acidsGas Chromatography-Mass SpectrometryArticleMARICULTURE03 medical and health sciencesNutraceuticalAlgaeFatty Acids Omega-6Fatty Acids Omega-31172 Environmental sciencessterolit010604 marine biology & hydrobiologyomega fatty acidsta1183ta1182GROWTH-RATEmikrolevätbiology.organism_classificationSterolomegarasvahapot030104 developmental biologyHuman nutrition416 Food Sciencelcsh:Biology (General)chemistry13. Climate actionDietary SupplementsStearidonic acidMarine Drugs; Volume 16; Issue 1; Pages: 3
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Technical Note on the quality of DNA sequencing for the molecular characterisation of genetically modified plants

2018

Abstract As part of the risk assessment (RA) requirements for genetically modified (GM) plants, according to Regulation (EU) No 503/2013 and the EFSA guidance on the RA of food and feed from GM plants (EFSA GMO Panel, 2011), applicants need to perform a molecular characterisation of the DNA sequences inserted in the GM plant genome. The European Commission has mandated EFSA to develop a technical note to the applicants on, and checking of, the quality of the methodology, analysis and reporting covering complete sequencing of the insert and flanking regions, insertion site analysis of the GM event, and generational stability and integrity. This Technical Note puts together requirements and r…

0106 biological sciences0301 basic medicineVeterinary (miscellaneous)[SDV]Life Sciences [q-bio]2405 Parasitologymolecularcharacterisationnext‐generation sequencingContext (language use)Plant ScienceComputational biologyGenetically modified cropsBiology01 natural sciencesMicrobiologyGenomeInsert (molecular biology)DNA sequencing03 medical and health sciencessymbols.namesake1110 Plant Sciencegenetically modified organismgenetic stabilityDNA sequencing1106 Food ScienceSanger sequencinggenetically modified organisms2404 Microbiologyrisk assessmentmolecular characterisation10079 Institute of Veterinary Pharmacology and ToxicologyGenetically modified organism3401 Veterinary (miscellaneous)Scientific Opinion030104 developmental biologyNGSsymbols570 Life sciences; biologyAnimal Science and ZoologyParasitologynext-generation sequencing1103 Animal Science and Zoology010606 plant biology & botanyFood ScienceVerification and validation
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Observations on midgut of Apis mellifera workers (Hymenoptera: Apoidea) under controlled acute exposures to a Bacillus thuringiensis-based biopestici…

2016

International audience; AbstractMorphostructural investigations have been carried out on Apis mellifera workers treated with single controlled acute exposures to a biopesticide containing Bacillus thuringiensis (Bt), to detect midgut changes until 96 h. Our findings show concentration-dependence of these changes, reflecting in different degrees on both mortality and behaviour. In particular, some midgut changes are also found 96 h after treatment. Our results show that the tested product does not affect survival at presumable environmental concentrations, so confirming the lesser toxicity of Bt-based biopesticides compared to other pesticides. However, in the light of the discovered long-te…

0106 biological sciences0301 basic medicineVeterinary medicinehoneybees[SDV]Life Sciences [q-bio]HymenopterahoneybeeBiology01 natural sciences03 medical and health sciencesBacillus thuringiensisBotanyBacillus thuringiensis var. aizawai/kurstakiBioassayskin and connective tissue diseasesBacillus thuringiensis var. aizawai /kurstakimorphostructural changesMidgutPesticidebiology.organism_classificationmortalitymorphostructural change3. Good healthApoidea010602 entomologyBiopesticide030104 developmental biologyhoneybees; Bacillus thuringiensis var. aizawai /kurstaki; bioassay; mortality; morphostructural changesbioassayInsect ScienceToxicitysense organs
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Kin and multilevel selection in social evolution: a never-ending controversy?

2016

Kin selection and multilevel selection are two major frameworks in evolutionary biology that aim at explaining the evolution of social behaviors. However, the relationship between these two theories has been plagued by controversy for almost half a century and debates about their relevance and usefulness in explaining social evolution seem to rekindle at regular intervals. Here, we first provide a concise introduction into the kin selection and multilevel selection theories and shed light onto the roots of the controversy surrounding them. We then review two major aspects of the current debate: the presumed formal equivalency of the two theories and the question whether group selection can …

0106 biological sciences0301 basic medicine[SDV]Life Sciences [q-bio]cooperationReviewKin selectionAltruism (biology)Biology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyBehavioral Ecology03 medical and health sciencesTheoretical Ecologycooperation; altruism; sociobiology; group selection; levels of selection; inclusive fitnessGeneral Pharmacology Toxicology and PharmaceuticsSelection (genetic algorithm)SociobiologyGeneral Immunology and Microbiology[SDV.BA]Life Sciences [q-bio]/Animal biologyinclusive fitnessInclusive fitnessArticlesGeneral Medicinelevels of selectionEpistemology[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoologygroup selection030104 developmental biologyGroup selectionaltruismEvolutionary EcologysociobiologySocial evolutionNeuroscienceSocial behaviorF1000Research
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Tubercle disease (Xanthomonas beticola) and other gall-malformed diseases of sugar beet roots: a review

2016

The sugar beet (Beta vulgaris) is an important plant in agriculture and sugar industry, and it is widely cultivated in European countries. Getting proper raw material of sugar beets (roots) is a problem for agriculture. Some disease symptoms observed on sugar beet roots are atypical tumor-like deformations. The causative agent of these deformations is known in the old literature as Xanthomonas beticola. The disease’s name in Poland is “tuberkuloza” and in the USA it refers to a description of a pocket disease—therefore we may consider those diseases to be the same. The clear description of X. beticola disease can be found in many phytopathological manuals printed in the past and nowadays. S…

0106 biological sciences0301 basic medicinegallbiologyTubercle030106 microbiologySugar industrysugar beetPlant ScienceDiseaseXanthomonas beticolaHorticulturebiology.organism_classification01 natural sciencesToxicology03 medical and health sciencesXanthomonasBotanyGallSugar beetSugarCausal organismAgronomy and Crop Science010606 plant biology & botanyJournal of Plant Diseases and Protection
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First report of tomato brown rugose fruit virus infecting sweet pepper in Italy

2020

In January 2020, about 85% of a red sweet pepper (Capsicum annuum) crop in a greenhouse located in Ragusa province (Sicily, Italy) showed virus-like symptoms. Symptoms consisted of a slight mosaic and discoloration of young leaves, vein clearing on young leaves, browning of the stem with strong necrosis located in the intersection of the secondary branches, partial necrosis of the vegetative apex and marbling, mosaic and distortion of the fruits (Fig. 1). It is important to note that in 2019 the same greenhouse was cultivated with tomato, which had been removed due to extensive infection caused by Tomato brown rugose fruit virus

0106 biological sciences0301 basic medicineoutbreakHealth Toxicology and Mutagenesisfungifood and beveragesOutbreakSettore AGR/12 - Patologia VegetaleTomato brown rugose fruit virusPlant Science030108 mycology & parasitologyBiology01 natural sciencesToBRFVCrop03 medical and health sciencesCapsicum annuumHorticulturePepperPepperRed Sweet PepperAgronomy and Crop Science010606 plant biology & botany
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