Search results for "Toxicology and food chain"
showing 7 items of 37 documents
Packaging
2019
Implication des enzymes dans la perception chimio-sensorielle : une piste dans les troubles olfacto-gustatifs induits par des xénobiotiques ?
2019
International audience
Reliable bioassays to detect potential hazard of paperboard food contact material extracts
2016
Food contact materials (FCM) represent a major economic issue and a large field of innovation. Food packaging production must be in compliance with the European Regulation 1935/2004: the third article specifies that FCM must not transfer their constituents to food in quantities which could endanger human health under normal or foreseeable conditions of use. Indeed, these materials are not inert and, in addition to started substances, Non-Intentionally Added Substances (NIAS) are able to be released into the food. NIAS can be contaminants from recycled materials, impurities, synthetic residues, new substances formed along the packaging production chain… Then, NIAS could represent a larget pa…
In vitro hazard assessment of nanoparticles developed for biomedical applications
2016
Nanotechnology is a growing sector in industry for twenty years and nanomaterials are currently used in numerous industrials applications. Their interest is based on their dimensions and their shape that give them very particular technological and biological properties. However, the development of these nanoparticles, their industrial preparation and integration into various products already involve an initial increased of human exposure (via inhalation, percutaneous and oral route). Another exposure pathway exists and is represented by drug injections. The risks associated with these new technologies and new products are still unclear. After a characterization step (zeta potential, TEM, TG…
Extraction d'éléments traces métalliques à partir de pains libanais et évaluation du danger de ces mélanges
2018
Parmi les éléments traces métalliques (ETM) qui peuvent être présents dans les aliments, certains sont connus comme étant toxiques et doivent faire l’objet d’une surveillance accrue. En ce qui concerne la sécurité sanitaire, il semble pertinent d’étudier le cas du pain, qui représente une part majoritaire de la ration journalière de la population libanaise. Dans une étude précédente, l’Institut de Recherche sur l’Agriculture Libanaise (IRAL) a déterminé la présence de plusieurs ETM (arsenic, cadmium, cobalt, chrome, mercure, nickel et plomb) dans le pain libanais. Bien que la toxicité de chaque ETM soit connue individuellement, il est important de tester la toxicité de ce mélange d’ETM, pré…
Genotoxicity assessment of a polycarbonate sol-gel coating and its precursors intended to be used for food contact
2016
Caffeine increases the expression of cystatin SN in human submandibular acinar-like HSG cells
2013
The study aimed at evaluating in vitro the effect of caffeine on expression of cystatin SN, a potential marker of sensitivity to bitterness in humans.Differentiation of human submandibular gland (HSG) cells was induced by culturing cells on Matrigel. Caffeine cytotoxicity was assessed over 3 days by the Resazurin test. Finally, effects of 5, 50 and 100μM caffeine exposure on cystatin SN expression were explored over 3 days by ELISA.At concentrations relevant to human adult plasma levels (5, 50 and 100μM), caffeine did not affect cell viability whether cells were differentiated or not. Cystatin SN levels were overall higher in differentiated cells and increased with time in both conditions. …