Search results for "Tp"
showing 10 items of 4688 documents
Analysis of TP53, Ki-Ras and P16INK4A promoter methylation as potential prognostic factors in patients with colorectal cancer
2007
Ready Access to Proquinazid Haptens via Cross-Coupling Chemistry for Antibody Generation and Immunoassay Development.
2015
17 pages, 4 tables, 5 figures.-- Publisher's PDF
Experimental Study of the Oriented Immobilization of Antibodies on Photonic Sensing Structures by Using Protein A as an Intermediate Layer
2018
[EN] A proper antibody immobilization on a biosensor is a crucial step in order to obtain a high sensitivity to be able to detect low target analyte concentrations. In this paper, we present an experimental study of the immobilization process of antibodies as bioreceptors on a photonic ring resonator sensor. A protein A intermediate layer was created on the sensor surface in order to obtain an oriented immobilization of the antibodies, which enhances the interaction with the target antigens to be detected. The anti-bovine serum albumin (antiBSA)-bovine serum albumin (BSA) pair was used as a model for our study. An opto-fluidic setup was developed in order to flow the different reagents and,…
Highly Sensitive Detection of Naphthalene in Solvent Vapor Using a Functionalized PBG Refractive Index Sensor
2012
We report an optical refractive index sensor system based on a planar Bragg grating which is functionalized by substituted γ-cyclodextrin to determine low concentrations of naphthalene in solvent vapor. The sensor system exhibits a quasi-instantaneous shift of the Bragg wavelength and is therefore capable for online detection. The overall shift of the Bragg wavelength reveals a linear relationship to the analyte concentration with a gradient of 12.5 ± 1.5 pm/ppm. Due to the spectral resolution and repeatability of the interrogation system, this corresponds to acquisition steps of 80 ppb. Taking into account the experimentally detected signal noise a minimum detection limit of 0.48 ± 0.05 pp…
Application of C1-Esterase Inhibitor During Reperfusion of Ischemic Myocardium
2001
Background—Complement activation during reperfusion of ischemic myocardium augments myocardial injury, and complement inhibition with C1-esterase inhibitor (C1-INH) at the time of reperfusion exerts marked cardioprotective effects in experimental studies. Application of C1-INH in newborns, however, was recently reported to have dangerous and even lethal side effects. This study addresses the essential role of dosage in studies using C1-INH.Methods and Results—Cardioprotection by C1-INH was examined in a pig model with 60 minutes of coronary occlusion followed by 120 minutes of reperfusion. C1-INH was administered intravenously 5 to 10 minutes before coronary reperfusion without heparin at a…
Step-by-Step Growth of HKUST-1 on Functionalized TiO2 Surface: An Efficient Material for CO2 Capture and Solar Photoreduction
2018
The present study reports on a simple preparation strategy of a hybrid catalyst, TiO2/HKUST-1, containing TiO2 anatase nanoparticles (NPs) with tailored morphology and photocatalytic activity coupled with a porous metal-organic framework (MOF), namely HKUST-1, as an advanced material for the CO2 photocatalytic reduction. In detail, TiO2/HKUST-1 catalyst was prepared via an easy slow-diffusion method combined with a step-by-step self-assembly at room temperature. The growth of crystalline HKUST-1 onto titania surface was achieved by functionalizing TiO2 nanocrystals, with phosphoesanoic acid (PHA), namely TiO2-PHA, which provides an intimate contact between MOF and TiO2. The presence of a cr…
Ancestral Reconstruction and Investigations of Genomic Recombination on some Pentapetalae Chloroplasts
2019
Abstract In this article, we propose a semi-automated method to rebuild genome ancestors of chloroplasts by taking into account gene duplication. Two methods have been used in order to achieve this work: a naked eye investigation using homemade scripts, whose results are considered as a basis of knowledge, and a dynamic programming based approach similar to Needleman-Wunsch. The latter fundamentally uses the Gestalt pattern matching method of sequence matcher to evaluate the occurrences probability of each gene in the last common ancestor of two given genomes. The two approaches have been applied on chloroplastic genomes from Apiales, Asterales, and Fabids orders, the latter belonging to Pe…
La evolución en los tribunales: aplicaciones forenses de las filogenias moleculares
2013
En las dos últimas décadas se ha generalizado el uso de pruebas genéticas en los tribunales, permitiendo la identificación de criminales a partir de restos biológicos, la determinación de paternidades o la identificación de cadáveres. Menos conocidas son las periciales basadas en el uso de filogenias moleculares. En ellas se estudia la ancestralidad común de organismos, normalmente virus o bacterias, para establecer su asociación a una fuente de infección. Desde el caso del dentista de Florida, que infectó con el VIH a varios de sus pacientes, hasta el más próximo del anestesista Juan Maeso, que transmitió el VHC a cerca de 300 pacientes, la teoría evolutiva tiene un papel esencial en estas…
Galda spēļu stāvokļu automātiska atpazīšana
2018
Darba mērķis ir izveidot Android lietotni, kas ļauj izmantot iebūvēto kameru, lai nobildētu galda spēli un automātiski atpazīst tajā galda spēles stāvokli. Galda spēles stāvoklis darbā tiek definēts kā kopa, kas satur atbildes uz sekojošiem jautājumiem: kāda spēle tiek spēlēta un kāds ir rezultāts. Darbā tiek izklāstīti praktiski risinājumi un algoritmi, tādi kā atpazīt un izgriezt spēles laukumu no attēla, atpazīt tajā spēles kauliņus un izvadīt spēles rezultātu.
Cefalea postpunción dural: correlación clínico-radiológica.
2015
El síndrome de hipotensión intracraneal ha sido ampliamente estudiado por parte de los profesionales de Neurología, de lo que se derivan gran cantidad de publicaciones en las que se describen sus manifestaciones clínicas, radiológicas y anatomopatológicas, así como diferentes teorías para explicar su fisiopatología. Por otro lado, se considera a la cefalea postpunción dural (CPPD) como síntoma del síndrome de hipotensión intracraneal de causa conocida, no habiendo sido estudiado como patología independiente del resto de las causas. La falta de estudios de una complicación de una técnica habitual en Anestesiología, como es la punción dural, con un diagnóstico casi exclusivamente clínico y qu…