Search results for "Transform"
showing 10 items of 3975 documents
Production of a Recombinant Catechol 2,3-Dioxygenase for the Degradation of Micropollutants
2017
Phenolic compounds such as catechol represent a particular type of micropollutant whose high stability prevents rapid decay and metabolization in the environment. We successfully cloned a catechol 2,3-dioxygenase (C2,3O) from Pseudomonas putida mt-2 and expressed it in Escherichia coli BER2566. The biomass isolated from shake-flask fermentations was used to partially purify the enzyme. The enzyme proved unstable in clarified liquid fractions (50 mM Tris buffer, pH 7.6) and lost more than 90% of its activity over 7 h at 25 °C. In the presence of 10% acetone, the process was slowed down and 30% residual activity was still present after 7 h incubation. Storage of the enzyme in clear liquid fr…
Species differences, influence of dose and application on biotransformation of phenol in fish.
1983
1. The metabolism of phenol in goldfish (Carassius auratus), rainbow trout (Salmo gairdneri) and goldenorfe ide (Leuciscus ideus melanotus) was compared. All three species produced phenyl sulphate, quinol sulphate and phenyl glucuronide. 2. The dose dependence of metabolism of phenol in goldfish was investigated. When the concn. of phenol was increased from 0.2 to 2 mg/l medium, that glucuronylated increased from 7 to 16% and that sulphated decreased from 63 to 47%. 3. The influence of mode of exposure on metabolism of phenol in goldfish was examined. Dietary exposure and uptake from medium was compared with i.p. injection. There was less metabolism in the order: dietary exposure greater th…
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
2004
The tumor suppressor p53 exerts its anti-neoplastic activity primarily through the induction of apoptosis. We found that cytosolic localization of endogenous wild-type or trans-activation–deficient p53 was necessary and sufficient for apoptosis. p53 directly activated the proapoptotic Bcl-2protein Bax in the absence of other proteins to permeabilize mitochondria and engage the apoptotic program. p53 also released both proapoptotic multidomain proteins and BH3-only proteins [Proapoptotic Bcl-2family proteins that share only the third Bcl-2homology domain (BH3)] that were sequestered by Bcl-xL. The transcription-independent activation of Bax by p53 occurred with similar kinetics and concentra…
Morphometrics of Second Iron Age ceramics - strengths, weaknesses, and comparison with traditional typology.
2014
12 pages; International audience; Although the potential of geometric morphometrics for the study of archaeological artefacts is recognised, quantitative evaluations of the concordance between such methods and traditional typology are rare. The present work seeks to fill this gap, using as a case study a corpus of 154 complete ceramic vessels from the Bibracte oppidum (France), the capital of the Celtic tribe Aedui from the Second Iron Age. Two outline-based approaches were selected: the Elliptic Fourier Analysis and the Discrete Cosine Transform. They were combined with numerous methods of standardisation/normalisation. Although standardisations may use either perimeter or surface, the res…
Resilience in Organizations and Societies: The State of the Art and Three Organizing Principles for Moving Forward
2021
AbstractResilience has attracted a multitude of scholars from diverse backgrounds and disciplines as it is a desired feature for responding to the adversities that modern societal systems face, not least the Covid-19 pandemic. Existing research displays little convergence on the definition of the concept making a robust theoretical framework and empirical understanding of resilience highly desirable. The aim of this chapter is to provide a more holistic understanding of the complex phenomenon of resilience from a multi-sectorial, cross-national and multidisciplinary perspective by proposing an original approach into the state of the art that might enhance future research. This chapter ident…
La transformación de una iglesia medieval o renacentista en barroca : teoría y resultados
2016
El oro : símbolo de lo transcendente en la pintura gótica. Su capacidad como elemento transformador, espiritual y plástico
2011
La transformación de la cultura clásica en el s.IV: el caso de Filastrio de Brescia
2018
Resumen: La obra de Filastrio de Brescia, Diversarum hereseon liber, compuesta a finales del siglo IV (380-90), se inserta en el género de la heresiología o catálogos adversus omnes haereses. De entre las 156 «herejías» que enumera este autor en su obra, además de los ya más que conocidos herejes o grupos de herejes como Simón mago, Valentinianos y otros, dedica un elevado número de entradas heréticas a refutar la tradición clásica. Analizamos en el presente trabajo la actitud de este clérigo ante los saberes clásicos. Centraremos nuestra atención en la transformación de aquellos conocimientos clásicos relacionados con la cosmografía, etnografía e historia en unos puramente bíblicos. Abstra…
Una escultura de José Esteve Bonet en La Orotava (Tenerife)
2020
En septiembre de 1784 el escultor José Esteve Bonet concluía una imagen de Santa Catalina de Siena que fue remitida a la isla de Tenerife semanas después, gracias a la mediación del canónigo de Xátiva Miguel Lobera. De ese destino, el responsable del ajuste, el dinero pagado por ella y las cualidades que mostraba como pieza vestidera hay constancia en un apunte que incluye el diario o Libro de la Verdad, documento de vital importancia a la hora de conocer la actividad de su taller entre 1762 y 1802. En este artículo proponemos la identificación de dicha obra con una escultura transformada y alterada en lo iconográfico, que forma parte del patrimonio acumulado durante el siglo XIX por la act…
Los años 70 en Valencia. La consolidación de estéticas y lenguajes individuales
1988
El tema surge con la necesidad de analizar las transformaciones estéticas y diferentes lenguajes plásticos en el arte realizado en Valencia. Analizaremos nueve artistas jóvenes: pintores (Jordi Teixidor, Soledad Sevilla, Carmen Calvo, R. Ramírez Blanco), escultores (Miquel Navarro, Joan Cardells, Ángeles Marco) y artistas iner-media (José María Yturralde y el grupo Poético).