Search results for "Transient"

Model-based specification and validation of the dual-mode adaptive MAC protocol

2018

Wireless sensor and actuator networks (WSANs) rely on MAC protocols to coordinate access to the wireless medium access and for managing the radio unit on each device. The dual-mode adaptive MAC (DMAMAC) protocol is a recently proposed protocol designed to reduce the energy consumption of the radio communication in WSANs. The DMAMAC protocol targets the industrial WSANs used for real-time process control. At its core, DMAMAC exploits the distinction between transient and steady of the controlled plant process to dynamically adapt the MAC superframe structure and thereby conserve energy. The switch between steady and transient mode of operation is a safety-critical part of the protocol. The c…

DNASE1L3 Deficiency, New Phenotypes and Evidence for a Transient Type I Interferon Signaling

2021

Introduction: Deoxyribonuclease 1 like 3 (DNASE1L3) is a secreted enzyme that has been shown to digest the extracellular chromatin derived from apoptotic bodies, and DNASE1L3 pathogenic variants have been associated to a lupus phenotype. It is unclear whether interferon signaling is sustained in DNASE1L3 deficiency in humans. Objectives: Here, we report on four patients with pathogenic variations in DNASE1L3, including 2 previously undescribed causal variants, and expand the phenotype from SLE to vasculitis with gut involvement. To explore whether or not the interferon cascade was strongly and sustainably induced, Interferon stimulated genes (ISGs) expression was assessed for each patient. …

The IceCube realtime alert system

2016

Following the detection of high-energy astrophysical neutrinos in 2013, their origin is still unknown. Aiming for the identification of an electromagnetic counterpart of a rapidly fading source, we have implemented a realtime analysis framework for the IceCube neutrino observatory. Several analyses selecting neutrinos of astrophysical origin are now operating in realtime at the detector site in Antarctica and are producing alerts to the community to enable rapid follow-up observations. The goal of these observations is to locate the astrophysical objects responsible for these neutrino signals. This paper highlights the infrastructure in place both at the South Pole detector site and at IceC…

Migrants' and refugees' health status and healthcare in Europe: A scoping literature review

2020

Abstract Background There is increasing attention paid to the arrival of migrants from outwith the EU region to the European countries. Healthcare that is universally and equably accessible needs to be provided for these migrants throughout the range of national contexts and in response to complex and evolving individual needs. It is important to look at the evidence available on provision and access to healthcare for migrants to identify barriers to accessing healthcare and better plan necessary changes. Methods This review scoped 77 papers from nine European countries (Austria, Cyprus, France, Germany, Greece, Italy, Malta, Spain, and Sweden) in English and in country-specific languages i…

2019

Background: Accurate assessment of hepatic fibrosis in patients with chronic HBeAg-negative Hepatitis B is of crucial importance not only to predict the long-term clinical course, but also to evaluate antiviral therapy indication. The aim of this study was to prospectively assess the utility of point shear wave elastography (pSWE) for longitudinal non-invasive fibrosis assessment in a large cohort of untreated patients with chronic HBeAg-negative hepatitis B virus (HBV) infection. Methods: 407 consecutive patients with HBeAg-negative HBV infection who underwent pSWE, transient elastography (TE) as well as laboratory fibrosis markers, including fibrosis index based on four factors (FIB-4), a…

Effectiveness of a screening program for HBV, HCV, and HIV infections in African migrants to Sicily

2021

BACKGROUND Migrants from Africa are vulnerable to viral infections during their journey. METHODS Migrants who arrived in western Sicily were offered early screening for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection. A questionnaire was administered to evaluate risk factors, and antiviral therapy was offered to subjects with active infection. A multiple regression analysis and adjusted odds ratio were obtained to evaluate risk factors. RESULTS Overall, 2,639 of 2,751 (95.9%) migrants who arrived between 2015 and 2017 accepted screening and 1,911 (72.4%) completed the questionnaire. HBsAg was positive in 257 (9.7%) migrants, 24 (0.9%) were …

Constraints on Cosmic Strings Using Data from the Third Advanced LIGO–Virgo Observing Run

2021

We search for gravitational-wave signals produced by cosmic strings in the Advanced LIGO and Virgo full O3 data set. Search results are presented for gravitational waves produced by cosmic string loop features such as cusps, kinks and, for the first time, kink-kink collisions.cA template-based search for short-duration transient signals does not yield a detection. We also use the stochastic gravitational-wave background energy density upper limits derived from the O3 data to constrain the cosmic string tension, $G\mu$, as a function of the number of kinks, or the number of cusps, for two cosmic string loop distribution models.cAdditionally, we develop and test a third model which interpolat…

Universal transport dynamics in a quenched tunnel-coupled Luttinger liquid

2016

The transport dynamics of a quenched Luttinger liquid tunnel-coupled to a fermionic reservoir is investigated. In the transient dynamics, we show that for a sudden quench of the electron interaction universal power-law decay in time of the tunneling current occurs, ascribed to the presence of entangled compound excitations created by the quench. In sharp contrast to the usual non universal power-law behavior of a zero-temperature non-quenched Luttinger liquid, the steady state tunneling current is ohmic and can be explained in terms of an effective quench-activated heating of the system. Our study unveils an unconventional dynamics for a quenched Luttinger liquid that could be identified in…

High rate of misclassification of fibrosis stage using transient elastography thresholds to prioritize HCV patients for antiviral treatment

2017

Cannabinoids, TRPV and nitric oxide: the three ring circus of neuronal excitability

2019

Endocannabinoid system is considered a relevant player in the regulation of neuronal excitability, since it contributes to maintaining the balance of the synaptic ionic milieu. Perturbations to bioelectric conductances have been implicated in the pathophysiological processes leading to hyperexcitability and epileptic seizures. Cannabinoid influence on neurosignalling is exerted on classic receptor-mediated mechanisms or on further molecular targets. Among these, transient receptor potential vanilloid (TRPV) are ionic channels modulated by cannabinoids that are involved in the transduction of a plethora of stimuli and trigger fundamental downstream pathways in the post-synaptic site. In this…