Search results for "Translation"
showing 10 items of 1324 documents
Migration for Knowledge. A Circumnavigation Between West andEast
2020
Migration of men has always been accompanied by a migration of knowledge, whether scientific or related to the tradition to which they belong. This article aims to highlight the transition of Greek sophia from the West to Persia and from Baghdad to the East. A movement of thought analyzed by Muslims experts and translators during the Middle Age. The process of translation and transmission of knowledge will accomplish an opposite periplus during the Napoleonic era, going back from the West to the Arab world. This process will give birth to the nahḍa phase, which is the cultural and literary awakening that will bring the Islamic countries living under the European colonization to meet and int…
Introduction. The aesthetics of migration: Reversals of marginality and the socio-political translation turn
2018
Translation has imposed itself with determination as a condition for intercultural and linguistic exchanges among human beings living in distant parts of the globe for millennia. Not only has it contributed to the understanding of sociocultural structures, political systems, and technological and digital processes, but it has also encouraged our knowledge of the world – strengthening our awareness of marginalities, liminalities and otherness, and, certainly, widening our interlinguistic and intercultural, as well as translinguistic and transcultural horizons. This volume ranges across disciplines and subjects in translation studies, critical migration and border studies, the visual and perf…
Constructing places and identities : migration and the role of translation in Leila Aboulela's The Translator and Lyrics Alley
2014
This study focuses on the role of translation as an instrument of construction of places and immigrant identities in the spaces of immigration. The investigation is based on a critical and theoretical correlation and interdisciplinary relation between theories of spaces/places, translation studies and literary forms of immigrant writing.
An Advanced Technique for User Identification Using Partial Fingerprint
2013
User identification is a very interesting and complex task. Invasive biometrics is based on traits uniqueness and immutability over time. In forensic field, fingerprints have always been considered an essential element for personal recognition. The traditional issue is focused on full fingerprint images matching. In this paper an advanced technique for personal recognition based on partial fingerprint is proposed. This system is based on fingerprint local analysis and micro-features, endpoints and bifurcations, extraction. The proposed approach starts from minutiae extraction from a partial fingerprint image and ends with the final matching score between fingerprint pairs. The computation o…
Yeast Translation Elongation Factor eIF5A Expression Is Regulated by Nutrient Availability through Different Signalling Pathways
2020
Translation elongation factor eIF5A binds to ribosomes to promote peptide bonds between problematic amino acids for the reaction like prolines. eIF5A is highly conserved and essential in eukaryotes, which usually contain two similar but differentially expressed paralogue genes. The human eIF5A-1 isoform is abundant and implicated in some cancer types
Museums as Disseminators of Niche Knowledge
2019
Accessibility has been facing several challenges within Audiovisual Translation Studies and has also gained great opportunities for its establishment as a methodologically and theoretically well-founded discipline. Audiovisual translation modes have achieved a crucial role in the transmission of what scholarly studies have discussed in relation to media accessibility as a set of services and practices providing access to audiovisual media content for persons with sensory impairment. Today accessibility has become a concept involving more and more universality, since it is extensively contributing to the dissemination of audiovisual and visual products about issues on minorities, and also ad…
The Escherichia coli Envelope Stress Sensor CpxA Responds to Changes in Lipid Bilayer Properties
2015
The Cpx stress response system is induced by various environmental and cellular stimuli. It is also activated in Escherichia coli strains lacking the major phospholipid, phosphatidylethanolamine (PE). However, it is not known whether CpxA directly senses changes in the lipid bilayer or the presence of misfolded proteins due to the lack of PE in their membranes. To address this question, we used an in vitro reconstitution system and vesicles with different lipid compositions to track modulations in the activity of CpxA in different lipid bilayers. Moreover, the Cpx response was validated in vivo by monitoring expression of a PcpxP-gfp reporter in lipid-engineered strains of E. coli. Our comb…
Modeling methods for studying post-translational and transcriptional modifying enzymes.
2012
Biological catalysis is a complex chemical process that involves not only electronic reorganization in the substrate but also the reorganization of the catalyst. This complexity is even larger in the case of post-transcriptional and post-translational modifications which may involve the interaction between two biomacromolecules. However, the development over the past decades of new computational methods and strategies is offering a detailed molecular picture of the catalytic event and a deep understanding of the mechanisms of chemical reactions in biological environments. Here we review the efforts made in the last years to model catalysis in post-transcriptional and post-translational proc…
Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: a QM/MM study
2019
AbstractCyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule to a Serine/Threonine residue of a peptide substrate. Due to the importance of this enzyme, and protein kinases in general, a detailed understanding of the reaction mechanism is desired. Thus, in this work the phosphoryl transfer reaction catalyzed by CDK2 was revisited and studied by means of hybrid quantum mechanics/molecular mechanics (QM/MM) calculations. Our results show that the base-assisted mechanism is preferred over the substrat…
Structure and Dynamics of RNA Guanine Quadruplexes in SARS-CoV-2 Genome. Original Strategies against Emerging Viruses
2021
Guanine quadruplex (G4) structures in the viral genome have a key role in modulating viruses' biological activity. While several DNA G4 structures have been experimentally resolved, RNA G4s are definitely less explored. We report the first calculated G4 structure of the RG-1 RNA sequence of SARS-CoV-2 genome, obtained by using a multiscale approach combining quantum and classical molecular modeling and corroborated by the excellent agreement between the corresponding calculated and experimental circular dichroism spectra. We prove the stability of the RG-1 G4 arrangement as well as its interaction with G4 ligands potentially inhibiting viral protein translation.