Search results for "Transmitter"
showing 10 items of 348 documents
Interference Cancellation for LoRa Gateways and Impact on Network Capacity
2021
In this paper we propose LoRaSyNc (LoRa receiver with SyNchronization and Cancellation), a second generation LoRa receiver that implements Successive Interference Cancellation (SIC) and time synchronization to improve the performance of LoRa gateways. Indeed, the chirp spread spectrum modulation employed in LoRa experiences very high capture probability, and cancelling the strongest signal in case of collisions can significantly improve the cell capacity. An important feature of LoRaSyNc is the ability to track the frequency and clock drifts between the transmitter and receiver, during the whole demodulation of the interfered frame. Due to the use of low-cost oscillators on end-devices, a s…
Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice.
2007
The endocannabinoid system (ECS) possesses neuromodulatory functions by influencing the release of various neurotransmitters, including GABA, noradrenaline, dopamine, glutamate and acetylcholine. Even though there are studies indicating similar interactions between the ECS and the serotonergic system, there are no results showing clear evidence for type 1 cannabinoid receptor (CB1) location on serotonergic neurons. In this study, we show by in situ hybridization that a low but significant fraction of serotonergic neurons in the raphe nuclei of mice contains CB1 mRNA as illustrated by the coexpression with the serotonergic marker gene tryptophane hydroxylase 2, the rate limiting enzyme for t…
Long-Term Behavioral Programming Induced by Peripuberty Stress in Rats Is Accompanied by GABAergic-Related Alterations in the Amygdala
2014
Stress during childhood and adolescence is a risk factor for psychopathology. Alterations in γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain, have been found following stress exposure and fear experiences and are often implicated in anxiety and mood disorders. Abnormal amygdala functioning has also been detected following stress exposure and is also implicated in anxiety and social disorders. However, the amygdala is not a unitary structure; it includes several nuclei with different functions and little is known on the potential differences the impact of early life stress may have on this system within different amygdaloid nuclei. We aimed here to evaluate pote…
Co-transmitter mediated facilitation by sympathetic nerve stimulation of evoked acetylcholine release from the rabbit perfused atria preparation.
1995
Rabbit atria were isolated with the extrinsic right sympathetic and vagus nerves attached and perfused with Tyrode solution. Acetylcholine overflow was determined after labelling of the transmitter stores with [14C]choline and fractionation of the radioactivity on cation exchange columns. Sympathetic nerve stimulation (SNS, 2 Hz, 3 min) carried out together with vagus nerve stimulation (VNS, 2 Hz, 3 min), but each SNS pulse preceding a vagal one by 19 ms, caused a facilitation of acetylcholine overflow of about 60% versus independent controls in the absence of SNS. Antagonists of putative neurotransmitters were tested to find out the prejunctional mediator involved in the facilitation. The …
Neurochemical substrates of the rewarding effects of MDMA: implications for the development of pharmacotherapies to MDMA dependence.
2015
In recent years, studies with animal models of reward, such as the intracranial self-stimulation, self-administration, and conditioned place preference paradigms, have increased our knowledge on the neurochemical substrates of the rewarding effects of 3,4-methylenedioxymetamphetamine (MDMA) in rodents. However, pharmacological and neuroimaging studies with human participants are scarce. Serotonin [5-hydroxytryptamine (5-HT)], dopamine (DA), endocannabinoids, and endogenous opiates are the main neurotransmitter systems involved in the rewarding effects of MDMA in rodents, but other neurotransmitters such as glutamate, acetylcholine, adenosine, and neurotensin are also involved. The most impo…
Decoupled Downlink-Uplink Coverage Analysis with Interference Management for Enriched Heterogeneous Cellular Networks
2016
Heterogeneous cellular networks (HetCNets) offer a promising solution to cope with the current cellular coverage crunch. Due to the large transmit power disparity, while following maximum power received (MPR) association scheme, a larger number of users are associated with macro-cell BS (MBS) than small-cell BSs (SBSs). Therefore, an imbalance load arrangement takes place across the HetCNets. Hence, using cell range expansion-based cell association, we can balance the load across the congested MBS. However, using MPR association scheme, users’ offloading leads to two challenges: 1) macro-cell interference , in which the MBS interferes with the offloaded users, and 2) coupled downlink-uplink…
Analysis of load balancing and interference management in heterogeneous cellular networks
2017
To meet the current cellular capacity demands, proactive offloading is required in heterogeneous cellular networks (HetCNets) comprising of different tiers of base stations (BSs), e.g., small-cell BSs (sBSs) and conventional macro-cell BSs (mBSs). Each tier differs from the others in terms of BS transmit power, spatial density, and association bias. Consequently, the coverage range of each tier BSs is also different from others. Due to low transmit power, a fewer number of users are associated to an sBS as compared with mBS. Thus, inefficient utilization of small-cell resources occurs. To balance the load across the network, it is necessary to push users to the underloaded small cells from …
On-body and off-body transmit power control in IEEE 802.15.6 scheduled access networks
2014
Wireless Body Area Networks (WBANs) have received much attention due to the possibility to be used in healthcare applications. For these applications, energy saving is a critical issue, as in many cases, batteries cannot be easily replaced. A transmit power control scheme, able to adapt to the variations of the wireless body channel, will allow consistent energy saving and longer battery life. In this paper we propose a transmit power control scheme suitable for IEEE 802.15.6 narrowband scheduled access networks, in which the transmission power is modulated frame by frame according to a run-time estimation of the channel propagation conditions. A simple and effective line search algorithm i…
Modulation of NMDA receptor function by cyclic AMP in cerebellar neurones in culture
2004
The signal transduction pathways involved in NMDA receptor modulation by other receptors remain unclear. cAMP could be involved in this modulation. The aim of this work was to analyse the contribution of cAMP to NMDA receptor modulation in cerebellar neurones in culture. Forskolin increases cAMP and results in increased intracellular calcium and cGMP that are prevented by blocking NMDA receptors. Similar effects were induced by two cAMP analogues, indicating that cAMP leads to NMDA receptor activation. It has been reported that phosphorylation of Ser897 of the NR1 subunit of NMDA receptors by cAMP-dependent protein kinase (PKA) activates the receptors. Forskolin increases Ser897 phosphoryla…
Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting.
2013
AIMS: To compare the constitutive and agonist-dependent endosomal trafficking of α(1A)- and α(1B)-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype. METHODS: Using CypHer5 technology and VSV-G epitope tagged α(1A)- and α(1B)-ARs stably and transiently expressed in HEK 293 cells, we analyzed by confocal microscopy the constitutive and agonist-induced internalization of each subtype, and the temporal relationship between agonist induced internalization and the increase in intracellular calcium (determined by FLUO-3 flouorescence), or the phosphorylation of ERK1/2 and p38 MAP kinases (determined by Western blot). RESULTS AND C…