Search results for "Trap"

showing 10 items of 2144 documents

Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells.

2020

Abstract Ethnopharmacological relevance Tetrapleura tetraptera is an African medicinal spice used in traditional medicine to treat several ailments including cancer. Aim of the study The present study was designed to evaluate the cytotoxicity of the dichloromethane-methanol (1:1) extract of the fruits of Tetrapleura tetraptera (TTF) and its constituents: (3R, 4S)-3,4-dimethyloxetan-2-one (1), luteolin (2), stigmasterol (4), 3-O-[6′-O-undecanoyl-β-D-glucopyranosyl]stigmasterol (6), olean-12-en-3-β-O-D-glucopyranoside (7), 3-O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranosylurs-12-en-28-oic acid (8), 3-O-β-D-glucopyranosyl-(1 → 3)-β-D-glucopyranosyl-27-hydroxyolean-12-ene-28-oic acid (9), methyl…

Tetrapleura tetrapteraPhytochemicalsApoptosis03 medical and health scienceschemistry.chemical_compoundInhibitory Concentration 500302 clinical medicineBetulinic acidNeoplasmsDrug DiscoveryCytotoxic T cellHumansTetrapleuraCytotoxicity030304 developmental biologyPharmacologychemistry.chemical_classificationMembrane Potential Mitochondrial0303 health sciencesReactive oxygen speciesbiologyDose-Response Relationship DrugPlant ExtractsHep G2 Cellsbiology.organism_classificationHCT116 CellsMolecular biologyAntineoplastic Agents PhytogenicDrug Resistance MultipleMatrix MetalloproteinasesOxidative StresschemistryApoptosisDrug Resistance Neoplasm030220 oncology & carcinogenesisCaspasesFruitCancer cellReactive Oxygen SpeciesLuteolinSignal TransductionJournal of ethnopharmacology
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A Methodology for Bilingual Lexicon Extraction from Comparable Corpora

2015

Dictionary extraction using parallel corpora is well established. However, for many language pairs parallel corpora are a scarce resource which is why in the current work we discuss methods for dictionary extraction from comparable corpora. Hereby the aim is to push the boundaries of current approaches, which typically utilize correlations between co-occurrence patterns across languages, in several ways: 1) Eliminating the need for initial lexicons by using a bootstrapping approach which only requires a few seed translations. 2) Implementing a new approach which first establishes alignments between comparable documents across languages, and then computes cross-lingual alignments between wor…

Text corpusInterlinguaComputer sciencebusiness.industrymedia_common.quotation_subjectBootstrapping (linguistics)computer.software_genrelanguage.human_languageParallel corporaBilingual lexiconResource (project management)languageQuality (business)Artificial intelligencebusinesscomputerWord (computer architecture)Natural language processingmedia_commonProceedings of the Fourth Workshop on Hybrid Approaches to Translation (HyTra)
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Positron detrapping from defects: A thermodynamic approach

1981

The rate of positron detrapping in thermal equilibrium from lattice defects has been calculated by relating it to the specific trapping rate. The results for vacancies, dislocations and surfaces each show a different temperature dependence for the escape rate. For vacancies a measure of the importance of the detrapping can be obtained from the ratio of the vacancy formation energy to the positron binding energy in the defect. The positronium desorption rate from a surface is also calculated and agreement with experimental results is found.

Thermal equilibriumPhysics and Astronomy (miscellaneous)ChemistryBinding energyGeneral EngineeringGeneral ChemistryTrappingPositroniumCondensed Matter::Materials SciencePositronLattice defectsDesorptionVacancy defectPhysics::Atomic and Molecular ClustersGeneral Materials ScienceAtomic physicsApplied Physics A Solids and Surfaces
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Effect of polyethelene oxide on the thermal degradation of cellulose biofilm - Low cost material for soft tissue repair in dentistry

2016

Background Bio cellulose is a byproduct of sweet tea fermentation known as kombusha. During the biosynthesis by bacteria cellulose chains are polymerized by enzyme from activated glucose. The single chains are then extruded through the bacterial cell wall. Interestingly, a potential of the Kombucha's byproduct bio cellulose (BC) as biomaterial had come into focus only in the past few decades. The unique physical and mechanical properties such as high purity, an ultrafine and highly crystalline network structure, a superior mechanical strength, flexibility, pronounced permeability to gases and liquids, and an excellent compatibility with living tissue that reinforced by biodegradability, bio…

Thermogravimetric analysisMaterials scienceBiocompatibilityResearchBiomaterial02 engineering and technologyBiodegradation:CIENCIAS MÉDICAS [UNESCO]010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical scienceschemistry.chemical_compoundchemistryChemical engineeringBiomaterials and Bioengineering in DentistryUNESCO::CIENCIAS MÉDICASPEG ratioUltrapure watermedicineCelluloseSwellingmedicine.symptom0210 nano-technologyGeneral DentistryJournal of Clinical and Experimental Dentistry
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Conversion of Organic Dyes into Pigments: Extraction of Flavonoids from Blackberries (Rubus ulmifolius) and Stabilization

2021

The blackberry’s color is composed mainly of natural dyes called anthocyanins. Their color is red–purple, and they can be used as a natural colorant. Anthocyanins are flavonoids, which are products of plants, and their colors range from orange and red to various shades of blue, purple and green, according to pH. In this study, the chemical composition of an extract obtained from blackberries was defined by LC-ESI/LTQOrbitrap/MS in positive and negative ionization mode. Furthermore, we investigated the adsorption process of blackberry extract using several inorganic fillers, such as metakaolin, silica, Lipari pumice, white pozzolan and alumina. The pigments exhibit different colors as a func…

Thermogravimetric analysispigmentsPharmaceutical SciencethermogravimetryblackberrieanthocyaninAnalytical Chemistrycolorimetric analysischemistry.chemical_compoundPigmentQD241-441AdsorptionpigmentDrug DiscoveryPhysical and Theoretical Chemistry<i>Rubus ulmifolius</i>LC-ESI/LTQOrbitrap/MSRubus ulmifoliusbiologyChemistryOrganic ChemistryExtraction (chemistry)biology.organism_classificationblackberriesRubus ulmifoliuChemistry (miscellaneous)Anthocyaninvisual_artvisual_art.visual_art_mediumMolecular MedicineAbsorption (chemistry)Colorimetric analysisNuclear chemistryMolecules
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Global extrapolation with a parallel splitting method

1992

Extrapolation with a parallel splitting method is discussed. The parallel splitting method reduces a multidimensional problem into independent one-dimensional problems and can improve the convergence order of space variables to an order as high as the regularity of the solution permits. Therefore, in order to match the convergence order of the space variables, a high order method should also be used for the time integration. Second and third order extrapolation methods are used to improve the time convergence and it was found that the higher order extrapolation method can produce a more accurate solution than the lower order extrapolation method, but the convergence order of high order extr…

Third orderUnit circleHigh Energy Physics::LatticeApplied MathematicsNumerical analysisConvergence (routing)Mathematical analysisExtrapolationSpace (mathematics)Unit squareMinimum polynomial extrapolationMathematicsNumerical Algorithms
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Survey sampling for functionnal data : building asymptotic confidence bands and considering auxiliary information

2011

When collections of functional data are too large to be exhaustively observed, survey sampling techniques provide an effective way to estimate global quantities such as the population mean function, without being obligated to store all the data. In this thesis, we propose a Horvitz–Thompson estimator of the mean trajectory, and with additional assumptions on the sampling design, we state a functional Central Limit Theorem and deduce asymptotic confidence bands. For a fixed sample size, we show that stratified sampling can greatly improve the estimation compared to simple random sampling. In addition, we extend Neyman’s rule of optimal allocation to the functional context. Taking into accoun…

Théorème Central Limite Fonctionnel[MATH.MATH-GM]Mathematics [math]/General Mathematics [math.GM]Données fonctionnelles[ MATH.MATH-GM ] Mathematics [math]/General Mathematics [math.GM]Bandes de confiance asymptotiques[MATH.MATH-GM] Mathematics [math]/General Mathematics [math.GM]No english keywordsÉchantillonnageSupremum de processus GaussiensEstimateur d’Horvitz-ThompsonBootstrapEstimateurs par modèle assisté
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Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter seque…

2006

AbstractThe human neuronal nitric oxide synthase (NOS1) gene is subject to extensive splicing. A total of 12 NOS1 mRNA species have been identified. They differ in their 5′ ends and are derived from 12 different first exons (termed exons 1a to 1l). Various cell lines whose NOS1 first exon expression patterns were representative of human brain, skin, and skeletal muscle were identified. These included A673 neuroepithelioma cells, SK-N-MC neuroblastoma cells, HaCaT keratinocyte-like cells, and C2C12 myocyte-like cells. In these cell lines, correlations were found between the exon 1 variants preferentially expressed and the promoter activities of their cognate 5′ flanking sequences. These data…

Transcription Genetic5' Flanking Region5' flanking regionReporter gene assaysSkeletal muscleNitric Oxide Synthase Type IBiologyKidneyHippocampusCell LineRT real-time PCRExonExon trappingGenes ReporterTestisGeneticsHumansRNA MessengerCloning MolecularLuciferasesPromoter Regions GeneticGeneSkinBinding SitesSplice site mutationReverse Transcriptase Polymerase Chain ReactionAlternative splicingGenetic VariationHeartExonsMolecular biologyAlternative SplicingRNA splicingCortexTandem exon duplicationProtein BindingTranscription FactorsGenomics
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Analysis of expression of the gene encoding for the nuclear autoantigen La/SS-B using reporter gene constructs.

1998

In earlier studies mRNA isoforms encoding for the nuclear autoantigen La were identified. In an alternative La mRNA form the exon 1 was replaced with the exon 1'. Moreover, exon 1' La mRNAs were found to start at different 5'-regions. In dependence on the 5'-start the exon 1' La mRNAs encoded for up to three open reading frames upstream of the La frame, which starts in the exon 2. The exon 1' was located in the intron about 70 nts downstream of the exon 1. The exon 1' La mRNA was proposed to be the result of a promoter switch in combination with an alternative splicing mechanism. The commonly used technique to study the expression of a eucaryotic gene is to fuse a reportergene immediately d…

Transcription GeneticRecombinant Fusion ProteinsMolecular Sequence DataBiophysicsGene ExpressionBiologyExon shufflingBiochemistryAutoantigensExonExon trappingStructural BiologyGenes ReporterGene expressionGeneticsHumansLuciferasesGeneGeneticsBase SequenceAlternative splicingIntronMolecular biologyOpen reading frameAlternative SplicingRibonucleoproteinsHeLa CellsBiochimica et biophysica acta
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New insights into the regulatory mechanisms of ppGpp and DksA on Escherichia coli RNA polymerase-promoter complex

2015

The stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind RNA polymerase (RNAP) and regulate gene expression to adapt bacteria to different environmental conditions. Here, we use Atomic Force Microscopy and in vitro transcription assays to study the effects of these modulators on the conformation and stability of the open promoter complex (RPo) formed at the rrnA P1, rrnB P1, its discriminator (dis) variant and lambda pR promoters. In the absence of modulators, RPo formed at these promoters show different extents of DNA wrapping which correlate with the position of UP elements. Addition of the modulators affects both DNA wrapping and RPo stability in a promo…

Transcription GeneticStringent responsemedicine.disease_causechemistry.chemical_compoundStructural BiologyRNA polymeraseGene expressionNucleotiderRNAPromoter Regions GeneticTranscription Initiation GeneticRibonucleotides/metabolismchemistry.chemical_classification0303 health sciencesDNA Bacterial/chemistry/ultrastructureEscherichia coli Proteins030302 biochemistry & molecular biologyBacterialEscherichia coli Proteins/metabolismDNA-Directed RNA PolymerasesBiological SciencesBacteriophage lambdaCell biologyEscherichia coli/enzymology/geneticsTranscriptionTranscription InitiationDNA BacterialGuanosine TetraphosphateBiologyPromoter Regions03 medical and health sciencesGeneticInformation and Computing SciencesmedicineGeneticsEscherichia coliEscherichia coli030304 developmental biologyPromoterGenes rRNADNAGene Expression Regulation BacterialRibonucleotidesequipment and suppliesMolecular biologyGuanosine TetraphosphateBacteriophage lambda/geneticschemistryGene Expression RegulationGenesbacteriaDNA-Directed RNA Polymerases/metabolismDNAEnvironmental SciencesGuanosine Tetraphosphate/metabolismDevelopmental Biology//purl.org/pe-repo/ocde/ford#1.06.07 [https]
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