Search results for "Tree"

showing 10 items of 1841 documents

Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Grupp…

2005

BACKGROUND: Although Ki-ras and TP53 mutations have probably been the genetic abnormalities most exhaustively implicated and studied in colorectal cancer (CRC) progression, their significance in terms of disease relapse and overall survival has not yet clearly been established. PATIENTS AND METHODS: A prospective study was carried out on paired tumor and normal colon tissue samples from a consecutive series of 160 previously-untreated patients, undergoing resective surgery for primary operable sporadic CRC. Mutations within the TP53 (exons 5-8) and Ki-ras (exon 2) genes were detected by PCR-SSCP analyses following sequencing. RESULTS: Mutation analyses of exons 5 to 8 of the TP53 gene showe…

MaleOncologyMultivariate analysisColorectal cancerpolymerase chain reactionmedicine.medical_treatmentLeucovorinColorectal Neoplasmmedicine.disease_causeBioinformaticsExonAntineoplastic Combined Chemotherapy ProtocolsProspective Studiesexongene mutationmultivariate analysiProspective cohort studysingle strand conformation polymorphism MeSH: Adenocarcinomaprotein p53 EMTREE medical terms: adultProto-Oncogene ProteinMutationarticleprotein domainclinical trialHematologyMiddle AgedagedItalypriority journalOncologyChemotherapy AdjuvantLymphatic MetastasisDisease ProgressionFemaleFluorouracilColorectal Neoplasmscancer tissueprognosiprospective studyHumansamplingmedicine.medical_specialtyfolinic acidgene sequenceAdenocarcinomarectum carcinomaProto-Oncogene Proteins p21(ras)outcomes researchProto-Oncogene ProteinsInternal medicinemedicineHumanscontrolled studyneoplasmsGeneNeoplasm StagingChemotherapyEMTREE drug terms: fluorouracillevamisoleAntineoplastic Combined Chemotherapy Protocolcontrolled clinical trialbusiness.industryfluorouracil; folinic acid; K ras protein; levamisole; protein p53 adult; aged; article; cancer tissue; clinical trial; codon; colon adenocarcinoma; colorectal surgery; controlled clinical trial; controlled study; exon; gene mutation; gene sequence; human; human cell; human tissue; Italy; major clinical study; male; multivariate analysis; oncology; outcomes research; polymerase chain reaction; prediction; priority journal; prognosis; prospective study; protein domain; rectum carcinoma; sampling; sequence analysis; single strand conformation polymorphism Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy Adjuvant; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Leucovorin; Levamisole; Lymphatic Metastasis; Male; Middle Aged; Multivariate Analysis; Mutation; Neoplasm Staging; Prospective Studies; Proto-Oncogene Proteins; ras Proteins; Tumor Suppressor Protein p53 [EMTREE drug terms]human cellLymphatic Metastasipredictionras Proteinmedicine.diseasemajor clinical studyhuman tissueProto-Oncogene Proteins p21(ras)K ras proteinProspective Studiecolon adenocarcinomaMultivariate AnalysisMutationras Proteinscolorectal surgerysequence analysicodonTumor Suppressor Protein p53businessAnnals of Oncology
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Characterization of street food consumption in palermo: possible effects on health

2011

Abstract Background Street Food (SF) consists of out-of-home food consumption and has old, historical roots with complex social-economic and cultural implications. Despite the emergence of modern fast food, traditional SF persists worldwide, but the relationship of SF consumption with overall health, well-being, and obesity is unknown. Methods This is an observational, cross-sectional study. The study was performed in Palermo, the largest town of Sicily, Italy. Two groups were identified: consumers of SF (n = 687) and conventional restaurant food (RES) consumers (n = 315). Study subjects answered a questionnaire concerning their health conditions, nutritional preferences, frequency of consu…

MalePediatricsRestaurantsCross-sectional studyMedicine (miscellaneous)Type 2 diabetesChoice BehaviorBody Mass IndexSurveys and QuestionnairesEpidemiologyPrevalenceNutritional Physiological PhenomenaYoung adultSicilylcsh:RC620-627Nutrition and DieteticsMiddle AgedNutrition Surveyslcsh:Nutritional diseases. Deficiency diseasesHypertensionBody CompositionFemalelcsh:Nutrition. Foods and food supplyAdultmedicine.medical_specialtylcsh:TX341-641Clinical nutritionInterviews as TopicFood PreferencesYoung AdultmedicineHumansObesityConsumption (economics)business.industryResearchStreet Food Obesity Hypertension public healthFeeding Behaviormedicine.diseaseObesityDietCross-Sectional StudiesSocioeconomic FactorsLinear ModelsFast FoodsEnergy IntakebusinessBody mass indexDemographyNutrition Journal
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Physical and cognitive doping in university students using the unrelated question model (UQM): Assessing the influence of the probability of receivin…

2018

Study objectives: In order to increase the value of randomized response techniques (RRTs) as tools for studying sensitive issues, the present study investigated whether the prevalence estimate for a sensitive item π̂$_{s}$ assessed with the unrelated questionnaire method (UQM) is influenced by changing the probability of receiving the sensitive question p. Material and methods: A short paper-and-pencil questionnaire was distributed to 1.243 university students assessing the 12-month prevalence of physical and cognitive doping using two versions of the UQM with different probabilities for receiving the sensitive question (p ≈ 1/3 and p ≈ 2/3). Likelihood ratio tests were used to assess wheth…

MaleQuestionnairesPeptide Hormoneslcsh:MedicineSocial SciencesBiochemistryMathematical and Statistical Techniques0504 sociologySociologySurveys and QuestionnairesStatisticsPrevalenceMedicine and Health SciencesHuman Performanceddc:796lcsh:ScienceMathematicsDoping in SportsMultidisciplinarySocial ResearchOrganic Compounds05 social sciencesDrugsCognitionMiddle AgedChemistryAthletic & outdoor sports & gamesNeurologyResearch DesignBehavioral PharmacologyPhysical SciencesFemaleSteroidsResearch ArticleAdultAdolescentUniversitiesSubstance-Related DisordersStreet drugsBayesian MethodResearch and Analysis Methods050105 experimental psychologyYoung AdultNeuropharmacologySensitive questionRecreational Drug UseHumans0501 psychology and cognitive sciencesStudentsErythropoietinPharmacologyPsychotropic DrugsBehaviorModels StatisticalSurvey ResearchIllicit Drugslcsh:RAmphetaminesOrganic ChemistryChemical CompoundsCorrection050401 social sciences methodsBiology and Life SciencesHormonesSample size determinationlcsh:QPLoS ONE
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Phylogenetic reconstruction of HCV genotype 1b dissemination in a small city centre: The Camporeale model

2008

Several seroepidemiological population-based surveys carried out in Italy have shown a high prevalence of hepatitis C virus (HCV) infection. Camporeale (CP), a small Sicilian town with a 10.4% prevalence of HCV mostly genotype 1b, probably represents a specific context, since intravenous drug addiction, and sexual promiscuity are almost absent. In order to reconstruct the pattern of introduction and diffusion of HCV in this ecological niche, the NS5 genomic region of 72 HCV genotype 1 isolates (39 from CP and 33 collected throughout Sicily) was amplified and sequenced. Sequences were aligned and analyzed by BioEdit, PAUP and BEAST, and their molecular evolution compared. Thirty-eight HCV ge…

MaleSettore MED/07 - Microbiologia E Microbiologia ClinicaUrban PopulationSequence analysisIatrogenic DiseasePopulationHepacivirusViral Nonstructural Proteinsmolecular epidemiologyMonophylyFlaviviridaecoalescent inference analysiPhylogeneticsVirologyGenotypePrevalenceCluster AnalysisHumanshepatitis C virueducationSicilyPhylogenyAgedGeneticsSettore MED/12 - Gastroenterologiaeducation.field_of_studyMolecular epidemiologybiologyPhylogenetic treeSequence Analysis RNAiatrogenic routeBayes TheoremHepatitis C ChronicMiddle Agedbiology.organism_classificationHepatitis CVirologyInfectious DiseasescommunityFemaleMonte Carlo MethodJournal of Medical Virology
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Status of Corynosoma (Acanthocephala: Polymorphidae) based on anatomical, ecological, and phylogenetic evidence, with the erection of Pseudocorynosom…

2006

The possession of genital spines has been considered as a key taxonomic trait to differentiate Corynosoma from other genera of the Polymorphidae. However, Corynosoma currently consists of 2 groups of species with clear ecological and morphological divergences: the "marine" group (with ca. 30 species) infects mammals and piscivorous birds in the marine realm, whereas the "freshwater" group (with ca. 7 species) infects waterfowl in continental waters. Species from these groups differ in shape of body and neck, trunk spination, lemnisci length and shape, testes arrangement, and number and shape of cement glands. We tested whether species from these 2 groups formed a monophyletic assemblage bas…

MaleZoologyFresh WaterAcanthocephalaHost-Parasite InteractionsPolymorphidaeBirdsMonophylyWaterfowlAnimalsAmphipodaSeawaterPseudocorynosomaEcology Evolution Behavior and SystematicsPhylogenyPhylogenetic treebiologyEcologyBird Diseasesbiology.organism_classificationPolymorphusCaniformiaDucksMinkKey (lock)ParasitologyFemaleCetaceaHelminthiasis AnimalAcanthocephalaOttersThe Journal of parasitology
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Probabilistic graphical model identifies clusters of EEG patterns in recordings from neonates

2018

Abstract Objectives In this paper we introduce a novel method for the evaluation of neonatal brain function via multivariate EEG (electroencephalography) signal processing and embedding into a probabilistic graph, the so called Chow-Liu tree. Methods Using 28 EEG recordings of preterm and term neonate infants the complex features of the EEG signals were constructed in the form of a Chow-Liu tree. The trees were embedded into a 3 dimensional Euclidean space. Clustering of specific EEG patterns was done by complete linkage algorithm. Results Our analytic tool was able to build clusters of patients with pathological EEG findings. In particular, we were able to make a visual proof on a 3d multi…

Malebrain monitoringComputer scienceautomated detectionModels Neurologicalmulti-dimensional scalingElectroencephalographyChow-Liu tree050105 experimental psychologyChow–Liu tree03 medical and health sciences0302 clinical medicineNeonatePhysiology (medical)medicineHumans0501 psychology and cognitive sciencesGraphical modelMultidimensional scalingCluster analysismedicine.diagnostic_testbusiness.industry05 social sciencesProbabilistic logicInfant NewbornBrainPattern recognitionTree (graph theory)Brain WavesSensory SystemsComplete linkageNeurologyFemaleNeurology (clinical)Artificial intelligencebusiness030217 neurology & neurosurgeryelectroencephalography
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Presence of viruses in wild eels Anguilla anguilla L, from the Albufera Lake (Spain)

2014

A virological analysis was conducted on wild eels from the Albufera Lake (Spain). A total of 179 individuals at different growth stages were collected in two different surveys (2004 and 2008). Presence of anguillid herpesvirus (AngHV-1), aquabirnavirus and betanodavirus was confirmed by PCR procedures in both surveys, although the number of detections was clearly higher in 2008 (83% of the eels analysed resulted positive for virus presence). AngHV-1 was the viral agent most frequently detected, followed by aquabirnaviruses. Betanodaviruses were detected by the first time in wild eels, and although the detections were only made by nested PCR, high percentage of positives were achieved. In ad…

Malefood.ingredientVeterinary (miscellaneous)Molecular Sequence DataReassortmentBetanodavirusAquatic ScienceBiologyPolymerase Chain ReactionVirusFish DiseasesViral ProteinsRNA Virus InfectionsfoodGenotypeAnimalsRNA VirusesAquabirnavirusPhylogenyPhylogenetic treeDNA VirusesSequence Analysis DNAAnguillabiology.organism_classificationVirologyDNA Virus InfectionsAnguillid herpesvirusSpainFemaleSeasonsNested polymerase chain reactionJournal of Fish Diseases
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Patterns of male-specific inter-population divergence in Europe, West Asia and North Africa

2000

summary We typed 1801 males from 55 locations for the Y-specific binary markers YAP, DYZ3, SRY "!)$" and the (CA)n microsatellites YCAII and DYS413. Phylogenetic relationships of chromosomes with the same binary haplotype were condensed in seven large one-step networks, which accounted for 95% of all chromosomes. Their coalescence ages were estimated based on microsatellite diversity. The three largest and oldest networks undergo sharp frequency changes in three areas. The more recent network 3‐1A clearly discriminates between Western and Eastern European populations. Pairwise Fst showed an overall increment with increasing geographic distance but with a slope greatly reduced when compared …

MalehaplotypePopulation geneticsVariation (Genetics)phylogenyAfrica NorthernModelsY Chromosomegenetic variabilitypopulation dynamicsNorthernDinucleotide RepeatsGenetics (clinical)education.field_of_studyPhylogenetic treeGeographyarticlechromosome analysislinguisticsStatisticalEastern europeanEuropeGeographypriority journalMicrosatelliteWesternmarker geneAsiaEvolutionPopulationPopulationmicrosatellite DNA; article; Asia; chromosome analysis; controlled study; Europe; genetic variability; geographic distribution; haplotype; human; linguistics; male; marker gene; normal human; North Africa; phylogeny; population dynamics; priority journal; Africa Northern; Asia Western; Dinucleotide Repeats; Europe; Evolution Molecular; Genetics Population; Geography; Haplotypes; Humans; Male; Microsatellite Repeats; Models Genetic; Models Statistical; Variation (Genetics); Y ChromosomeY chromosomeEvolution MolecularGeneticGeographical distancegeographic distributionAsia WesternGeneticsHumanscontrolled studyhumannormal humaneducationModels StatisticalModels GeneticHaplotypeGenetic VariationMolecularNorth AfricaSettore BIO/18 - GeneticaGenetics PopulationHaplotypesEvolutionary biologyAfricamicrosatellite DNAMicrosatellite Repeats
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Postoperative Costs Associated With Outcomes After Cardiac Surgery With Extracorporeal Circulation: Role of Antithrombin Levels

2012

Objective: To study the impact on postoperative costs of a patient's antithrombin levels associated with outcomes after cardiac surgery with extracorporeal circulation. Design: An analytic decision model was designed to estimate costs and clinical outcomes after cardiac surgery in a typical patient with low antithrombin levels (= 63.7%). The data used in the model were obtained from a literature review and subsequently validated by a panel of experts in cardiothoracic anesthesiology. Setting: Multi-institutional (14 Spanish hospitals). Participants: Consultant anesthesiologists. Measurements and Main Results: A sensitivity analysis of extreme scenarios was carried out to assess the impact o…

Malemedicine.medical_specialtyExtracorporeal Circulationextracorporeal circulationCardiotonic AgentsMyocardial InfarctionAntithrombinsDrug Costslaw.inventionPostoperative ComplicationsDrug TherapylawSurveys and QuestionnairesThromboembolismAtrial FibrillationmedicineCardiopulmonary bypassHumansBlood TransfusionCardiac Surgical ProceduresCardiothoracic anesthesiologyAverage costAgedPostoperative Carebusiness.industryAntithrombinExtracorporeal circulationDecision TreesAntithrombin ActivityLength of StayMiddle AgedSurgeryCardiac surgeryStrokeIntensive Care UnitsantithrombinAnesthesiology and Pain MedicineTreatment OutcomeSpainHealth Care SurveysEmergency medicineCosts and Cost AnalysisFemaleKidney DiseasesCardiology and Cardiovascular Medicinebusinesscardiopulmonary bypassHospital staymedicine.drug
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"KARYOTYPE, BANDING AND rDNA FISH IN THE SCARAB BEETLE ANOPLOTRUPES STERCOROSUS (COLEOPTERA SCARABAEOIDEA: GEOTRUPIDAE). DESCRIPTION AND COMPARATIVE …

2004

Six specimens of Anoplotrupes stercorosus (Coleoptera Scarabaeoidea: Geotrupidae) were analysed using conventional staining, banding techniques and fluorescent in situ hybridization with a ribosomal probe (rDNA FISH). Detailed karyotype description was also joined to a comparative analysis between present data and those previously reported for Thorectes intermedius [Chromosome Res. 7 (1999) 1]. The two species, both belonging to the tribe Geotrupini, show the same modal number but different autosomal morphology which is in contrast with the high chromosome stability argued for Geotrupinae during the last three decades. Moreover, a detailed comparison reveals the occurrence of a plesiomorphi…

Malemedicine.medical_specialtyGeneral Physics and AstronomyZoologyScarabaeoideaTribe (biology)DNA RibosomalStructural BiologyGeotrupidaemedicine18S rDNA FISHAnimalsGeneral Materials ScienceIn Situ Hybridization FluorescencebiologyPhylogenetic treecytogeneticCytogeneticsKaryotypeCell BiologyRibosomal RNAbiology.organism_classificationAnoplotrupes stercorosusChromosome BandingColeopteraKaryotypingFemaleColeoptera Scarabaeoidea Geotrupidae
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